Benzocaine and menthol as anesthetics for the African cichlid Aulonocara nyassae

Ferreira, Andre Lima; Silva, Walisson de Souza e; Neves, Luanna do Carmo; Ferreira, Nathália Soares; Takata, Rodrigo; Luz, Ronald Kennedy

doi:10.1007/s10499-020-00561-w

Cited by 12 publications

(4 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Around 73% of the included studies assessed the anaesthetic effects of these compounds in juvenile stages while 30% studied monoterpene anaesthesia in fish adult stages. The time to reach deep anaesthesia ranged from 1.0 min (Ferreira et al, 2021; Pereira‐da‐Silva et al, 2014) to 3.2 min (Araújo et al, 2021; Aydin, 2020) while time for recovery varied from 1.2 min (Ferreira et al, 2020) to 9.7 min (He et al, 2020). The recommended concentration varied from as low as 35 mg/L (Mazandarani & Hoseini, 2017) up to 1600 mg/L (Yousefi, Hoseinifar, et al, 2018).…”

Section: Resultsmentioning

confidence: 99%

A meta‐analytic review of monoterpene for fish anaesthesia

et al. 2023

View full text Add to dashboard Cite

The use of anaesthetic agents has been increasing to address the welfare needs of different fish species in scientific and aquaculture practices. MS‐222 is the most used synthetic anaesthetic but some limitations and side effects have been reported. Natural substances have been used as potential substitutes with clove oil playing an important role due to its eugenol content. Yet, other monoterpenes have shown anaesthetic properties in different fish species. As such, a quantitative assessment has been conducted to explicitly relate and summarise the use of monoterpenes with described anaesthetic properties in fish. A combined PubMed, Web of Science, Scopus, PubMed Central and Europe PMC electronic database search was performed, from January 2002 to August 2022, following the PRISMA guidelines. Out of 1555 articles retrieved from the literature search, 30 English reports met the criteria for inclusion in the meta‐analysis through a generic inverse‐variance method (random‐effects model) and according to the fish age. The findings show a total of 10 different monoterpenes with high homogeneity and effectiveness in inducing anaesthesia and recovery according to the fish anaesthetic criteria. Further subgroup analysis showed these effects were independent of fish age. Meta‐regression of the included studies revealed an inverse linear association between anaesthesia induction and recovery time and water bath temperature while no further correlation was found with other confounding factors (body weight, water pH and dissolved oxygen levels). Although further studies will be required, this meta‐analysis provides robust evidence that different monoterpenes serve as an attractive and effective alternative for fish anaesthesia although water bath temperature also played an important role in anaesthesia outcome.

show abstract

Section: Resultsmentioning

confidence: 99%

A meta‐analytic review of monoterpene for fish anaesthesia

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Fish were then transferred to another 1 L beaker with supplemental aeration (clean water with no anesthetic), to regain normal swimming balance (Small 2003;Ross and Ross 2008), during which recovery time and VF were also evaluated. Fish of the 0 mg L − 1 treatment (control) were monitored for 10 min, as also performed by Ferreira et al (2020).…”

Section: Animals and Environmental Acclimationmentioning

confidence: 99%

“…In general, anesthetized and/or sedated sh may experience reduced metabolic rates (lower ventilatory rate and ammonia excretion) (Sena et Barbas et al 2020) and reduced physical injury. However, the effects of a given anesthetic are associated with the intrinsic characteristics of the species (Readman et al 2017) and its size (Ribeiro et al 2015;Tarkhani et al 2017;Ferreira et al 2020), which makes previous characterization necessary.…”

Section: Introductionmentioning

confidence: 99%

Oxidative responses in small juveniles of Colossoma macropomum anesthetized and sedated with Ocimum gratissimum L. essential oil

Ferreira

Silva

et al. 2023

Preprint

Self Cite

View full text Add to dashboard Cite

This study evaluated the use of essential oil of Ocimum gratissimum (EOOG) for anesthesia and in transport of Colossoma macropomum. Experiment 1, Test 1, anesthesia induction and recovery times were determined using different EOOG concentrations (0, 20, 50, 100, 200, 300 mg L− 1), with two size classes: Juveniles I (0.86 g) and Juveniles II (11.46 g) (independent tests in a completely randomized design). Based on the results of Test 1, in Test 2 Juveniles II were exposed to EOOG concentrations: 0, 20, 100 mg L− 1. Tissue samples were collected immediately after induction and 1 h post-recovery, to assess oxidative status variables. Experiment 2, Juveniles I (0.91 g) and Juveniles II (14.76 g) were submitted to transport in water with different concentrations of EOOG (0, 5, 10 mg L− 1) (independent tests in a completely randomized design). The effects on oxidative status variables were evaluated. Concentrations between 50 and 200 mg L− 1 EOOG can be indicated for Juveniles I, while concentrations between 50 and 100 mg L− 1 EOOG for Juveniles II. The concentration of 100 mg L− 1 EOOG was able to prevent oxidative damage in the liver. In Experiment 2, the concentrations of 5 and 10 mg L− 1 EOOG added to the transport water caused sedation for both studied size classes of juveniles and did not cause oscillations in water quality variables nor any mortality. The concentration of 10 mg L− 1 EOOG improved the oxidative status. It can be concluded that EOOG can be used for anesthesia and transport of C. macropomum.

show abstract

“…For example, EO of Ocimum gratissimum L. for Lophiosilurus alexandri (BOAVENTURA et al, 2020) and Oreochromis niloticus (FERREIRA et al, 2021b), EO of Ocimum basilicum for C. macropomum (VENTURA et al, 2021), EOs of Ocimum americanum and Lippia alba for O. niloticus (RUCINQUE et al, 2021), and EO Lippia sidoides for C. macropomum (BRANDÃO et al, 2021). These anesthetic efficacy studies in fish are based on a fast induction time of anesthesia (< 3 min) and a short recovery time (< 5 min) as described by KEENE et al (1998) and ROSS & ROSS (2008); and their ideal concentrations depend on the fish species and size (ROSS & ROSS, 2008;READMAN et al, 2017;FERREIRA et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Hesperozygis ringens essential oil as an anesthetic for Colossoma macropomum during biometric handling

et al. 2023

Self Cite

View full text Add to dashboard Cite

This study evaluated the effectiveness of the essential oil of Hesperozygisringens (EOHR) for anesthesia of Colossomamacropomum by documenting hematological and blood biochemical responses after biometric handling. In Experiment 1, juveniles (14.12 ± 3.53 g) were exposed to different concentrations of EOHR: 0 (control), 75, 150, 300 and 450 µL L-1 (n=10 fish for each concentration), to determine times for induction and recovery from anesthesia, as well as its effects on ventilatory frequency (VF). Based on these results, Experiment 2 evaluated the effects of 0 (control), 75 (with induction and recovery times outside that recommended for fish anesthesia) and 150 µL L-1 EOHR (within recommended times) on hematological and biochemical variables of juveniles (20.52 ± 3.47 g) after anesthesia and after 24 h of recovery (n = 6 fish for each concentration and collection time). Survival was 100%. Induction time showed a quadratic effect of EOHR concentration. Recovery time did not differ among EOHR concentrations. Concentrations between 150 and 450 µL L-1 EOHR caused rapid induction (< 3 min) and recovery (< 5 min). EOHR concentration affected VF. The concentration of 150 µL L-1 EOHR had little influence on hematological and biochemical parameters of C. macropomum of 20 g.

show abstract

Benzocaine and menthol as anesthetics for the African cichlid Aulonocara nyassae

Cited by 12 publications

References 33 publications

A meta‐analytic review of monoterpene for fish anaesthesia

A meta‐analytic review of monoterpene for fish anaesthesia

Oxidative responses in small juveniles of Colossoma macropomum anesthetized and sedated with Ocimum gratissimum L. essential oil

Hesperozygis ringens essential oil as an anesthetic for Colossoma macropomum during biometric handling

Contact Info

Product

Resources

About