Benzimidazole scaffold as a potent anticancer agent with different mechanisms of action (2016–2023)
Fatma Fouad Hagar,
Samar H. Abbas,
Eman Atef
et al.
Abstract:Benzimidazole scaffolds have potent anticancer activity due to their structure similarity to nucleoside. In addition, benzimidazoles could function as hydrogen donors or acceptors and bind to different drug targets that participate in cancer progression. The literature had many anticancer agents containing benzimidazole cores that gained much interest. Provoked by our endless interest in benzimidazoles as anticancer agents, we summarized the successful trials of the benzimidazole scaffolds in this concern. Mor… Show more
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