Benign tumours and tumour-like lesions in the oral cavity: a retrospective analysis

Abstract

Introduction: Oral lesions are divided into non-neoplastic lesions, potentially malignant lesions and neoplastic lesions. More clinical data are needed to determine their helpful clinical pattern. Aim: To present the epidemiological, clinical and histopathological characteristics of the oral lesions. Material and methods: The retrospective study group comprised records of 208 patients which were reviewed according to selected epidemiological and clinical features. All the biopsy specimens were classified into: reactive lesions, precancerous lesions/potentially malignant lesions, salivary gland pathologies, benign and malignant tumours. Results: The lower lip was the most common site involved followed by buccal and vestibular mucosa. The most frequent diagnoses were fibroma, mucocele and papilloma. The predominant pathomorphological forms were nodule and bulla. The most frequent salivary gland pathology was mucocele. Fibroma was the most frequent pathomorphological diagnosis, followed by mucocele and reactive lesions such as irritation fibroma (IF) and granuloma. Conclusions: In cases of oral mucosal lesions, we propose the following algorithm: the exclusion of all odontogenic and iatrogenic causes; the detection and elimination of harmful habits, parafunctions and irritants from the oral cavity especially from the vestibule of the oral cavity and from the lips; all surgical treatment should be performed only after the proper detection and elimination of causative factors to decrease the risk of recurrence; excisional biopsy or in more diffuse lesions incisional biopsy is recommended to confirm clinical diagnosis; and consideration of other factors that can modify the clinical pattern of oral lesions, such as oral hygiene, systemic diseases, and drugs.

Clinical Features and Management of Oral Nonodontogenic Masses in Children

“…Oral cavity involvement by a solitary and peripheral plexiform neuro broma in patients with no other signs of neuro bromatosis is uncommon [36]. NF-1 is an autosomal dominant and multisystem genetic disorders, known as Recklinghausen syndrome, nearly 50% of NF-1 have a positive family history [37].…”

Dental MRI of Oral Soft-Tissue Tumors—Optimized Use of Black Bone MRI Sequences and a 15-Channel Mandibular Coil

“…These oral mucosa disorders can be difficult to diagnose and treat, as they include a broad spectrum from benign indolent to invasive malignant lesions of various etiologies. Many of these oral soft-tissue lesions tend to become chronic and affect the patient’s quality of life [ 1 , 2 , 3 ].…”

Oral cavity tumors in children. Diagnostic approach

“…All oral lesions are divided into three groups, including non-neoplastic lesions, potentially malignant disorders and neoplastic lesions, and are also sub-divided into 10 major subcategories: normal tissue, inflammatory and infectious lesions, cystic lesions, adaptive reactions, potentially malignant disorders, autoimmune and metabolic diseases, vascular and hemodynamic anomalies, hamartomatous lesions and congenital alterations, benign neoplasms and malignant neoplasms. Despite the progress made in recent years in the diagnosis and treatment of oral lesions, more clinical data are needed to establish their helpful clinical pattern [9].…”