Benign sleep myoclonus in neonate: a diagnostic dilemma for neonatologist

Sharma, Deepak; Murki, Srinivas; Oleti, Tejo Pratap

doi:10.1136/bcr-2014-206626

Cited by 4 publications

(6 citation statements)

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“…This feature of BNSM helps in its recognition as well as its differentiation from neonatal seizures. 1 The majority of the neonates have generalized myoclonia, mainly in the distal part of limbs, jerking is of short duration, lasting 10 to 20 seconds though they may persist for more than 30 minutes. 1,8,9 The general condition of the child is unaffected and there are no associated abnormalities on neurodevelopmental examination.…”

Section: Discussionmentioning

confidence: 99%

“…Benign neonatal sleep myoclonus (BNSM) is a nonepileptic movement disorder and self-limiting disorder that develops in the neonatal period. 1 This phenomenon of the first weeks of life characterized by neonatal onset myoclonic jerks during non-rapid eye movement (NREM) sleep, and consistent cessation with arousal with no electroencephalographic changes. 1 Myoclonus is a clinical sign characterized by sudden, brief, jerky, shocklike involuntary movements.…”

Section: Introductionmentioning

confidence: 99%

“…1 This phenomenon of the first weeks of life characterized by neonatal onset myoclonic jerks during non-rapid eye movement (NREM) sleep, and consistent cessation with arousal with no electroencephalographic changes. 1 Myoclonus is a clinical sign characterized by sudden, brief, jerky, shocklike involuntary movements. 2 Other have suggested that a transient disorder of the serotoninergic system might play a role in the pathogenesis of this disorder.…”

Section: Introductionmentioning

confidence: 99%

“…Electrographic seizures do not occur during events. [1][2][3] By definition, the involuntary movements only occur in sleep but may be severe and prolonged enough to mimic convulsive status epilepticus. They may be worsened by touch, simple restraint, and anticonvulsant treatment, but cease promptly on arousal.…”

mentioning

confidence: 99%

“…An EEG may be required at times to distinguish BNSM from neonatal convulsion. 1 The jerky movements should be differentiated from jitteriness/clonus, which occur due to poor myelination of corticospinal tract in neonates. The closest alternative diagnosis is benign myoclonus of early infancy, which may rarely have a neonatal onset and have a normal EEG but these typically occur when the infant is awake.…”

mentioning

confidence: 99%

See 4 more Smart Citations

Benign neonatal sleep myoclonus in a child

Marcos

Saharso

Gunawan

2019

Int J Contemp Pediatr

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Benign neonatal sleep myoclonus (BNSM), is a disorder generally mistaken for seizures during the newborn period. Benign neonatal sleep myoclonus is featured by myoclonic "lightninglike" jerks of the extremities that exclusively occur during sleep; it is not associated with epilepsy that occur only during sleep and cease abruptly when the child is agitated. This case reported was a 50 days-old baby boy with a history suggestive of abnormal movements for limbs noted over the preceding 7 days. Diagnosis of BNSM in infant based on history taking, clinical manifestation, and with no electroencephalographic changes. BNSM is usually not associated with any other neurologic impairment and spontaneously subsides within the first year of life. Its importance lies in the differential diagnosis with the epileptic, especially myoclonic, seizures of infancy. BNSM can be misinterpreting for neonatal seizures or even neonatal status epilepticus, the recognition of benign sleep myoclonus of infancy is imperative to elude unnecessary diagnostic studies and treatments.

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