Benign Sinonasal Masses: A Clinicopathological and Radiological Profile

Nepal, Ajit; Chettri, Shyam Thapa; Jj, Joshi; Karki, Smriti

doi:10.3126/kumj.v11i1.11015

Cited by 14 publications

(11 citation statements)

References 14 publications

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“…Nasal polyps were the commonest non-neoplastic sinonasal masses followed by rhinosporidiosis. This is similar to the study conducted by Nepal et al 6 Most common benign neoplastic lesion was angiofibroma (11.9%), whereas malignant lesions included 9.52% of all nasal masses (75% of squamous cell carcinoma and 25% of adenoid cystic carcinoma). According to the study by Sachan et al, 7 commonest non-neoplastic lesion was also nasal polyps (83%), followed by rhinosporidiosis (2%), angiofibroma being the commonest benign neoplastic lesion (7%), and malignant masses accounting for 5% of the total study subjects.…”

Section: Discussionsupporting

confidence: 91%

“…Male predominance was found in case of both neoplastic and non-neoplastic sinonasal masses, but the difference was less in case of non-neoplastic lesions (non-neoplastic: 16 males, 14 females to neoplastic: 10 males, 2 females). The highest incidence of the sinonasal masses was between 16 and 30 years of age, which is similar to the study result of Nepal et al 6 Contrast-enhanced computed tomography PNS was done in 50% patients, which revealed bony erosion in two cases of angiofibroma and two cases of malignant sinonasal tumors.…”

Section: Discussionsupporting

confidence: 88%

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A Study of Neoplastic and Non-neoplastic Sinonasal Masses at a Tertiary Center

Sachdeva¹,

Naskar²

2009

An International Journal Clinical Rhinology

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Aim:The aim of this study was to evaluate all the cases of sinonasal masses based on histopathology into neoplastic and non-neoplastic lesions and to study their clinical and radiological presentations. Patients were subjected to thorough clinical examinations and radiological investigations, which included digital X-ray paranasal sinus (PNS) and contrast-enhanced computed tomography PNS, and diagnosis was confirmed by nasal biopsy for histopathology reports. Results and observations:A total of 42 patients were studied, of which 71.43% were non-neoplastic and 28.57% were neoplastic. Nasal polyps were the commonest non-neoplastic lesions (61.91%). Most common benign neoplastic lesion was angiofibroma (11.9%), while the commonest malignant neoplastic mass was found to be squamous cell carcinoma (7.14%). There was one case of adenoid cystic carcinoma. Conclusion:Patients with sinonasal masses may present with trivial complaints, but proper evaluation of all the cases will enable us to make specific diagnosis and treat them accordingly.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 88%

A Study of Neoplastic and Non-neoplastic Sinonasal Masses at a Tertiary Center

Sachdeva¹,

Naskar²

2009

An International Journal Clinical Rhinology

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“…They represented 9.5-12.5 % of head and neck and 1 % of all ALMs, respectively [7,8,27]. Only a single case of ALM was identified among 331 consecutive benign sinonasal masses (0.3 %) [42]. Since the first description by Maesaka et al [9], no more than 38 well documented cases have been reported in the English literature, mainly as single case reports .…”

Section: Discussionmentioning

confidence: 99%

Angioleiomyoma of the Sinonasal Tract: Analysis of 16 Cases and Review of the Literature

Agaimy

Thompson

2015

Head and Neck Pathol

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Angioleiomyoma (ALM; synonyms: angiomyoma, vascular leiomyoma) is an uncommon benign tumor of skin and subcutaneous tissue. Most arise in the extremities (90 %). Head and neck ALMs are uncommon (~10 % of all ALMs) and those arising beneath the sinonasal tract mucosa are very rare (<1 %) with 38 cases reported so far. We herein analyzed 16 cases identified from our routine and consultation files. Patients included seven females and nine males aged 25-82 years (mean 58; median 62). Symptoms were intermittent nasal obstruction, sinusitis, recurrent epistaxis, and a slow-growing mass. Fifteen lesions originated within different regions of the nasal cavity and one lesion was detected incidentally in an ethmoid sinus sample. Size range was 6-25 mm (mean 11). Histologically, all lesions were well circumscribed but non-encapsulated and most (12/16) were of the compact solid type superficially mimicking conventional leiomyoma but contained numerous compressed muscular veins. The remainder were of venous (2) and cavernous (2) type. Variable amounts of mature fat were observed in four cases (25 %). Atypia, necrosis, and mitotic activity were absent. Immunohistochemistry showed consistent expression of smooth muscle actin (12/12), h-caldesmon (9/9), muscle-specific actin (4/4), variable expression of desmin (11/14) and CD56 (4/6), and absence of HMB45 expression (0/11). The covering mucosa was ulcerated in 6 cases and showed squamous metaplasia in one case. There were no recurrences after local excision. Submucosal sinonasal ALMs are rare benign tumors similar to their reported cutaneous counterparts with frequent adipocytic differentiation. They should be distinguished from renal-type angiomyolipoma. Simple excision is curative.

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“…The maxillary sinus is the most common site of origin, while the most common histological type is squamous cell carcinoma. 19,20 It is rarely encountered before the 4th decade of life. In this study, all the tumours originated in the maxillary sinus except 2 cases, one of which was nasopharyngeal carcinoma extending into sinuses & nasal cavity, eroding the lateral wall of nasal cavity, and another was an olfactory neuroblastoma extending from cribriform plate level to entire nasal cavity.…”

Section: Discussionmentioning

confidence: 99%

“…The mainstay of radiologic examination in the tumors of nasal cavity is not only to make a differential diagnosis but also to explore the origin, dimensions, orientation of the mass to the surrounding structures, contours and the contrast enhancement of the tumor. 19 Radiological investigations may also help in understanding the type of pathology, extension of lesion and associated sinus pathology. It is to be used as first line tool for diagnosis of malignant cases where extent of disease is important factor for further management.…”

Section: Discussionmentioning

confidence: 99%

Clinical, pathological and radiological profile of sinonasal masses in patients presenting to a tertiary care center: a retrospective observational study

Bhalodiya

Prajapati

Hingol

et al. 2020

Int J Otorhinolaryngol Head Neck Surg

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Background: The study aimed to assess the profile of various pathological conditions that present with nasal mass in Indian patients.Methods: This is a retrospective observational study of 43 patients of sinonasal masses who visited GMERS Medical College and Hospital, Sola, Ahmedabad, India during May 2017 to March 2020. The clinical profile of sinus or nasal masses were observed along with their radiological features on computed tomography scans of paranasal sinuses. The age and gender sub group were also assessed for distribution of these conditions. Most of the patients were managed with surgical techniques. Results: Overall, clinical profile of 43 patients was observed. The clinicopathological examination aided by endoscopic and imaging studies revealed that 20 (46.5%) patients presented with the non-neoplastic masses and remaining were with neoplastic masses (53.5%). The overall M: F ratio was 1.5:1. Most of the patients belong to 11-30 years age group. The most common symptoms were mass in the nasal cavity and nasal discharge. Polyps were most common lesions seen (25.6%). Surgical intervention in the form of biopsy, excision of mass, functional endoscopic sinus surgery was performed in all patients.Conclusions: This study gives an insight into various lesions presenting as sinonasal masses and their clinical and pathological profile. Overall, surgical management in form of excision by endoscopic or external approach is effective modality of treatment supplemented with appropriate medical management.

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Benign Sinonasal Masses: A Clinicopathological and Radiological Profile

Abstract: Background

Cited by 14 publications

References 14 publications

A Study of Neoplastic and Non-neoplastic Sinonasal Masses at a Tertiary Center

A Study of Neoplastic and Non-neoplastic Sinonasal Masses at a Tertiary Center

Angioleiomyoma of the Sinonasal Tract: Analysis of 16 Cases and Review of the Literature

Clinical, pathological and radiological profile of sinonasal masses in patients presenting to a tertiary care center: a retrospective observational study

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