Benign Rheumatoid Arthritis of the Aged

Corrigan, A. B.; Robinson, R. G.; Terenty, T R; Dick‐Smith, J. B.; Walters, D.

doi:10.1136/bmj.1.5905.444

Cited by 79 publications

(23 citation statements)

References 9 publications

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“…An acute onset was noted in all cases, oedema and polyarthritis occurring concurrently. However, three patients (Nos 13,16,18) complained of inflammatory pain and stiffness of the shoulders in the three weeks before distal arthritides and oedemas began. All the patients had a pitting oedema spreading on the dorsum of the hands and the distal part of the forearms.…”

Section: Methodsmentioning

confidence: 99%

“…Two had died of an unrelated disease (patients 5, 7) and four were not traced (patients 3, 4, 6, 8); the disease course of these six patients was evaluated only during the period of initial follow up in our department. Five other patients could not be seen after the initial period of follow up (patients 2,9,13,14,20), but relevant data were obtained from their practitioners. For the remaining 13 patients, clinical, radiological, and biological evaluation was performed in our department, with the last assessment in 1993.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Remitting seronegative symmetrical synovitis with pitting oedema: disease or syndrome?

Schaeverbeke

Fatout

Marce

et al. 1995

Annals of the Rheumatic Diseases

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Remitting seronegative symmetrical synovitis with pitting oedema: disease or syndrome?

Schaeverbeke

Fatout

Marce

et al. 1995

Annals of the Rheumatic Diseases

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“…A number of observational studies have reported that patients with late symptom onset have a more favorable outcome than those with early-onset RA (2,(13)(14)(15)(16). However, of growing concern in an aging population are findings that patients with late-onset RA have a worse prognosis than early-onset patients, in terms of DAS28 score, HAQ score, and degree of radiographic damage (3,5).…”

Section: Introductionmentioning

confidence: 99%

Influence of age and sex on functional outcome over time in a cohort of patients with recent‐onset inflammatory polyarthritis: Results from the Norfolk arthritis register

Camacho¹,

Verstappen²,

Lunt³

et al. 2011

Arthritis Care & Research

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Objective. It has been found that women with rheumatoid arthritis (RA) have a poorer prognosis than men. However, the impact of age at symptom onset is unclear. We investigated the relationship between these factors and functional disability in patients with recent-onset inflammatory polyarthritis (IP). Methods. A total of 3,666 patients (66% women) were registered with the Norfolk Arthritis Register between 1990 and 2008. Functional disability was assessed using the Health Assessment Questionnaire (HAQ), adjusted for age at HAQ completion. Linear random-effects models were used to examine HAQ score over time, by sex and age at symptom onset (early ‫؍‬ age <55 years, late ‫؍‬ age 55-74 years, very late ‫؍‬ age >75 years). Results. Women had higher HAQ scores over time than men (mean difference 0.29; 95% confidence interval [95% CI] 0.25, 0.34). Men with late-onset IP had lower baseline HAQ scores than men with early onset (mean difference ؊0.14; 95% CI ؊0.29, ؊0.001). Women had comparable baseline HAQ scores at all ages of onset. Both sexes showed the greatest rate of disability progression in patients with very late onset. Those with early onset had a steady level of disability over time. Adjustment for treatment received, comorbidities, and RA subgroup analysis produced results that were largely similar to the initial analysis. Conclusion. Female patients have higher HAQ scores than male patients; patients with early symptom onset show the smallest sex difference. Older age at symptom onset is associated with an increasingly steep trajectory of disability progression. The impact of sex on outcome is evident at baseline, whereas the impact of age at symptom onset becomes apparent during long-term followup.

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“…[1][2][3][4][5][6][7][8][9][10][11][12][13] The data in previous reports were discordant in some respects, but equal distribution of the disease between men and women, a tendency towards large joint involvement, an increased erythrocyte sedimentation rate (ESR), less seropositivity, a stormy onset, and a good prognosis have been mentioned as characteristic manifestations of ORA.…”

mentioning

confidence: 99%

Older age onset rheumatoid arthritis with or without osteoarthritis.

Inoue

Shichikawa

Nishioka

et al. 1987

Annals of the Rheumatic Diseases

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SUMMARYThe clinical features of a group of 79 patients with older age onset rheumatoid arthritis (ORA) were compared with those of a group of 414 patients with younger age onset rheumatoid arthritis. The ORA group contained approximately equal numbers of men and women, were less rheumatoid factor positive, had a raised erythrocyte sedimentation rate, lower HLA-DR4 positivity, and a tendency towards larger joint involvement at the onset of the disease. These features have been reported by many authors except for the lower DR4 positivity. Of these features, the lower prevalence of rheumatoid factor positivity and the tendency towards larger joint involvement at the onset were characteristic of a subset of patients with ORA who had had osteoarthritis before the onset of rheumatoid arthritis. It is suggested that osteoarthritic large joints may be susceptible to the occurrence of rheumatoid synovitis at the onset of the disease, but that the osteoarthritis inducing factor may be negatively related to the progression of rheumatoid arthritis.

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Benign Rheumatoid Arthritis of the Aged

Cited by 79 publications

References 9 publications

Remitting seronegative symmetrical synovitis with pitting oedema: disease or syndrome?

Remitting seronegative symmetrical synovitis with pitting oedema: disease or syndrome?

Influence of age and sex on functional outcome over time in a cohort of patients with recent‐onset inflammatory polyarthritis: Results from the Norfolk arthritis register

Older age onset rheumatoid arthritis with or without osteoarthritis.

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