Benign Prostatic Hypertrophy: Amino Acid Therapy for Symptomatic Relief

Prostatism: Clinical, radiological, and urodynamic aspects

“…From pharmacological trials involving placebo, great variation in symptomatology has also been registered in placebo groups (Castro, Griffiths, and Edwards, 1971;Abrams, 1977;Caine, Perlberg, and Meretyk, 1978). Symptoms have further been shown to be unreliable in assessment of bladder outflow obstruction when compared to urodynamic studies (Damrau, 1962;Castro et al, 1969;Castro and Griffiths, 1972;Abrams and Feneley, 1978). Three of these studies concur that the irritative prostatism symptoms had no statistical significant correlation to urodynamic infravesical obstruction.…”

Multilayer adsorption of amino acids on oxidized cellulose

“…The interest to AA is caused by their extensive use in the pharmaceutical and health industries. Glycine and alanine are used in the treatment of benign prostatic hyperplasia [9] and schizophrenia [10]. Other AA (proline, tryptophane, and 4-aminobutanoic and 6-aminocaproic acid) are also widespread drugs.…”

Estrogenic Management of Benign Prostatism, Including Early and Poor‐risk Cases: 7‐year Experience*

“…Good results can be expected from estrogenic treatment in the majority of patients who have symptomatic benign prostatism. For example, one urologist (4) administered intermittent courses of stilbestrol (3)(4)(5) mg daily for four to six weeks), and noted a decrease of residual urim• Yolumc in Pvery other patient. Results probably arc improved if the hormonal therapy is instituted during the earlier stages of BPH.…”

“…Wildbolz (4) estimated that prolonged improvement may occur in as many as one-third of patients with symptomatic BPH who refuse prostatectomy, with or without instrumentation. As an example of spontaneous improvement, Damrau (5) reported reduction of prostatic enlargement in 5 of 45 patients following the administration of a glycine-alanine-glutamic acid capsule, and a comparable incidence of improvement among those receiving a placebo.…”