Benign Pleomorphic Adenoma of the Larynx: A Case Report

Som, Peter M.; Feuerstein, Sidney S.; Nagel, Barry D.; Strauss, Lotte

doi:10.1177/000348947908800120

Cited by 15 publications

(4 citation statements)

References 6 publications

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“…It occurs most commonly in the parotid gland, with a frequency 10 times greater than that in any of the other major salivary glands, but may also occur in the upper aerodigestive tract or skin [1,2,4,6]. The commonest site of origin of PA in the upper respiratory tract is the nasal cavity, mainly in the septum, and PA originating in the nasopharynx is extremely rare.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic resection of pleomorphic adenoma arising in the nasopharynx

Roh

Jung

Rha

et al. 2005

Acta Oto-Laryngologica

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Pleomorphic adenoma is the commonest benign tumor of the salivary glands. It has rarely been reported arising in the nasopharynx. A pleomorphic adenoma originating from the left lateral wall of the nasopharynx was found in a 61-year-old female who presented with nasal obstruction and intermittent epistaxis. It was successfully removed by combined transnasal and transoral surgery under endoscopic visualization. Endoscope-guided surgery may be helpful for the complete resection of benign nasopharyngeal tumors whilst minimizing injury to the Eustachian tube openings or velopharynx.

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Section: Discussionmentioning

confidence: 99%

Endoscopic resection of pleomorphic adenoma arising in the nasopharynx

Roh

Jung

Rha

et al. 2005

Acta Oto-Laryngologica

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“…Most tumors commonly present as submucosal subglottic masses of which around 20 cases have been reported in literature. [3][4][5][6]…”

Section: Discussionmentioning

confidence: 99%

“…A variety of approaches have been described in literature. Pharyngotomy 3,4 has been advocated especially for supraglottic lesions. Laryngofissure 5 has been used in patients with glottic or subglottic disease.…”

mentioning

confidence: 99%

Laser Resection of Subglottic Pleomorphic Adenoma

Nair¹,

Pai²,

Chaturvedi³

et al. 2010

International Journal of Head and Neck Surgery

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A 48 years old male was referred to our center, a specialized tertiary comprehensive cancer center with a history of progressively worsening dyspnea since 6 months. The patient was admitted in a general hospital for stridor and treated with steroids following which his stridor subsided. Further investigations with rigid laryngoscopy under general anesthesia revealed a subglottic mass. The biopsy was reported as pleomorphic adenoma and he was referred to us for further management.On presentation, the patient had no stridor or hoarseness. On flexible laryngoscopy, a pedunculated mass with a broad base was seen arising 1 cm below the level of the vocal cords, extending inferiorly for about 1 cm and occluding 30% of the subglottic lumen. Both the vocal cords were normal in appearance and mobility (Fig. 1). The rest of the tracheobronchial tree was normal. A computed tomography (CT) scan of the larynx revealed a lobulated mass in the subglottis arising from the posterior wall measuring 1.2 × 1.2 × 1.4 cm, extending anterior and abutting the right lateral wall of subglottis with no erosion of the underlying cartilage (Figs 2 and 3). The patient underwent endolaryngeal endoscopic CO 2 laser (Lumenis TM Israel, 3.5 W, superpulse mode) resection of the mass under general anesthesia using apnea technique. The base of the mass was completely resected with wide margins. The cricoid cartilage was not exposed. Postoperative recovery was uneventful.The histopathology report demonstrated a biphasic tumor in submucosa consisting of epithelial nests, trabeculae and tubules embedded in a fibromyxoid stroma (Fig. 4A). The epithelial component composed of 2 cell types: epithelial cells arranged in duct like structures or cords and myoepithelial cells situated at around the ducts and in solid Fig. 1: Flexible laryngoscopy picture showing presence of pedunculated mass arising from posterior wall of subglottis, compromising laryngeal lumen AbstractTumors arising from the minor salivary glands in the larynx are rare. The most common tumors occurring here are adenoid cystic carcinomas. 1 Among the benign tumors, pleomorphic adenoma is the most common. 1 We present a case of subglottic pleomorphic adenoma which was managed by endolaryngeal endoscopic CO 2 laser surgery. Laser as a primary treatment modality for the treatment of subglottic pleomorphic adenomas has not been well-described, as only one case has been reported in literature using this modality.

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“…As pleomorphic adenoma is a benign tumour, most authors would agree that local excision with a tumour-free margin is adequate, with the advantage of preserving laryngeal function. Cotelingam et al (1977) and Som et al (1979) reported one case each of supraglottic pleomorphic adenoma treated successfully by lateral pharyngotomy and supraglottic laryngectomy with conservation of laryngeal function.…”

Section: Treatmentmentioning

confidence: 99%

Pleomorphic adenoma of the larynx

Zakzouk

1985

J. Laryngol. Otol.

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Benign Pleomorphic Adenoma of the Larynx: A Case Report

Cited by 15 publications

References 6 publications

Endoscopic resection of pleomorphic adenoma arising in the nasopharynx

Endoscopic resection of pleomorphic adenoma arising in the nasopharynx

Laser Resection of Subglottic Pleomorphic Adenoma

Pleomorphic adenoma of the larynx

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