Benign Pediatric Orbital Tumors

Katowitz, William R.; Fries, Peter D.; Kazim, Michael

doi:10.1007/978-3-319-60814-3_35

Cited by 2 publications

(5 citation statements)

References 227 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…61 Orbital imaging demonstrates a well-circumscribed, irregular, and relatively homogenous mass within orbital soft tissues that enhances moderately with contrast. 63 Bony destruction and erosion can be seen on larger, aggressive lesions. 62 Diagnosis is made through open biopsy with or without tumor debulking, to provide adequate tissue for histopathologic evaluation.…”

Section: Primary Epithelial Malignancies Of the Lacrimal Glandmentioning

confidence: 99%

“…For smaller anterior lesions, a biopsy can often be achieved through an anterior orbitotomy via a transcutaneous incision or transconjunctival incision depending on location. 63 A comprehensive systemic evaluation is required for suspected orbital RMS with the help of a pediatric oncologist.…”

Section: Primary Epithelial Malignancies Of the Lacrimal Glandmentioning

confidence: 99%

“…Multimodal therapy has significantly reduced the morbidity and mortality of RMS. 63,64 Current management consists of a combination of surgical biopsy, resection, or debulking followed by systemic chemotherapy and radiation. Complete resection or maximal debulking can be attempted at the initial time of diagnosis but remains controversial due to risk of injury to nearby orbital structures such as the optic nerve.…”

Section: Primary Epithelial Malignancies Of the Lacrimal Glandmentioning

confidence: 99%

“…Chiasmal lesions are less likely to demonstrate funduscopic findings but may demonstrate visual field defects. 75,76 CT and MRI classically demonstrate enlargement of the optic nerve in a fusiform pattern and/or involvement of the optic chiasm. OPG typically appear hypointense on T1-weighted imaging and hyperintense on T2-weighted imaging.…”

Section: Optic Pathway Gliomasmentioning

confidence: 99%

See 3 more Smart Citations

Primary Malignant Orbital Tumors

Laplant

Cockerham

2021

J Neurol Surg B Skull Base

View full text Add to dashboard Cite

Objective Primary orbital malignancy is rare. Awareness of the characteristic clinical and imaging features is imperative for timely identification and management. Surgery remains an important diagnostic and treatment modality for primary orbital malignancy, but determining the optimal surgical approach can be challenging. The purpose of this article is to explore recent advances in the diagnosis, management, and surgical approaches for primary orbital malignancies. Design In this review, the clinical presentation, imaging features, and medical and surgical management of primary orbital malignancies with representative cases will be discussed. Setting Outpatient and inpatient hospital settings. Participants Patients with diagnosed primary orbital malignancies. Main Outcome Measures Descriptive outcomes. Results Advancements in orbital imaging, microsurgical techniques, and multimodal therapy have improved the diagnosis and management of primary orbital malignancies. Special considerations for biopsy or resection are made based on the tumor's location, characteristics, nearby orbital structures, and goals of surgery. Minimally invasive techniques are supplanting traditional approaches to orbital surgery with less morbidity. Conclusions Advances in imaging technologies and surgical techniques have facilitated the diagnosis and management of primary orbital malignancies. Evolution toward less invasive orbital surgery with focus on preservation and restoration of function is underway.

show abstract

Section: Primary Epithelial Malignancies Of the Lacrimal Glandmentioning

confidence: 99%

Section: Primary Epithelial Malignancies Of the Lacrimal Glandmentioning

confidence: 99%

Section: Primary Epithelial Malignancies Of the Lacrimal Glandmentioning

confidence: 99%

Section: Optic Pathway Gliomasmentioning

confidence: 99%

See 2 more Smart Citations

Primary Malignant Orbital Tumors

Laplant

Cockerham

2021

J Neurol Surg B Skull Base

View full text Add to dashboard Cite

show abstract

“…Chiasmal lesions may show deficiencies in the visual field. 8,10 If the tumor arises within the hypothalamus, endocrinopathies like accelerated growth and precocious puberty may manifest. 11 Plexiform neurofibroma (PNF) usually involves sensory nerves in the orbit or eyelid.…”

Section: Introductionmentioning

confidence: 99%

Eye and orbital malignancies: An overview

Rao

2023

IJOOO

View full text Add to dashboard Cite

Orbital tumors are classified based on where they occur within the orbit as intraconal, extraconal, and intracanalicular lesions. Patients with larger orbital lesions may present with proptosis and diplopia due to extraocular muscle involvement or mass effect, whereas dry eye symptoms are associated with lacrimal gland lesions. Rhabdomyosarcoma (RMS) is the most common primary orbital malignancy in children that invades the base of the skull from the orbit. The most common primary malignant orbital tumors in adults are the lymphoproliferative lesions of the orbit and adnexa, which accounts for up to 20% of all orbital masses and malignant lymphoma is common in above 60 years. Orbital lymphomas are mostly anterior and extraconal lesions. Hemangiopericytomas are rare encapsulated tumors with a propensity towards the superior orbit. They are often more aggressive and can spread through the orbit and intracranially. Optic pathway gliomas (OPG) are the most frequent tumors of the optic nerve. In most individuals, proptosis is the primary symptom unless it is localised posterior to the optic chiasma. Computed tomography (CT), magnetic resonance imaging (MRI), or both is regards as the gold standard for imaging of ocular and orbital malignancy. CT is useful for visualization of bony structures and identifying tumor erosion or hyperostosis of bone, while MRI is advised for imaging soft tissue structures and apical tumors. Conservative management with clinical and radiographic studies is often chosen unless patients have progressive optic nerve dysfunction, visual loss, proptosis, progressive visual field changes, or evidence of hypothalamic invasion. Management of progressive disease typically consists of chemotherapy, in select cases, radiotherapy, as supplementary or alternative therapy to surgery. In this paper, we reviewed several articles on orbital and ocular cancers and summarized. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

show abstract

Benign Pediatric Orbital Tumors

Cited by 2 publications

References 227 publications

Primary Malignant Orbital Tumors

Primary Malignant Orbital Tumors

Eye and orbital malignancies: An overview

Contact Info

Product

Resources

About