Benign pancreatic hyperenzymemia-Gullo's syndrome: focus on this clinical challenge. A monocentric retrospective study

Catanzaro, R; Sciuto, Morena; Adamo, Giuseppe; Guarrera, Martina; Marotta, Francesco

doi:10.23736/s0026-4806.19.06046-4

Cited by 4 publications

(2 citation statements)

References 21 publications

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“…While Vanella et al (2019) did not find s-MRCP or EUS, which are more costly and invasive, to be more valuable than magnetic resonance cholangio-pancreatography (MRCP), Amodio et al recommend s-MRCP as an effective diagnostic tool for follow-up in BPH patients [11,12]. Therefore, it must be borne in mind that expensive tests do not guarantee a proper diagnosis, and performing unnecessary medical procedures should be avoided [13]. The research by Italian scientists who confirm that BPH patients have a quality of life similar to healthy patients seems to be optimistic in determining the proper diagnosis of Gullo's Syndrome [14].…”

Section: Discussionmentioning

confidence: 99%

Gullo’s Syndrome – case report

Rycyk¹,

Furtak²,

Mądro³

et al. 2020

J Pre Clin Clin Res.

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Benign pancreatic hyperenzymemia (BPH) or Gullo's Syndrome is a persistent elevation of pancreatic enzymes activity, observed for at least one year, with no pancreatic disorder. This diagnosis is extremely important because it allows us to avoid many unnecessary examinations performed during the diagnostic process. The case is presented of a 25-year-old man who was examined for recurrent elevated lipase and amylase serum values over a time period of 2 years who presented with non-specific abdominal complaints. Interestingly, his routine tests showed sustained elevated serum amylase and lipase activity. He was intensively diagnosed due to pancreatic hyperenzymemia, but no pancreatic disease was detected. The observation lasted two years. The serum lipase and serum amylase levels continued to increase after that time. This diagnosis requires attention because BPH can be the first symptom of pancreatic cancer.

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Section: Discussionmentioning

confidence: 99%

Gullo’s Syndrome – case report

Rycyk¹,

Furtak²,

Mądro³

et al. 2020

J Pre Clin Clin Res.

View full text Add to dashboard Cite

show abstract

“…On the other hand, many researchers emphasize the economic aspect of repeated procedures in order to establish the proper diagnosis of BPH [ 17 , 18 ]. They admit that due to the fact of the weak awareness, doctors perform too many procedures in this group of patients [ 17 ].…”

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confidence: 99%