Benign Osteoid-Producing Bone Lesions: Update on Imaging and Treatment

Trotta, Brian M.; Fox, Michael G.

doi:10.1055/s-0033-1342968

Cited by 15 publications

(3 citation statements)

References 36 publications

(80 reference statements)

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“…In contrast, OS exhibits an aggressive periosteal reaction and severe destructive characteristics 16 , 17 . The absence of pleomorphic atypical nuclei, mitotic activity, and tumor permeation favors the diagnosis of OB over osteosarcoma, as confirmed by previous articles 11 , 18 , 19 . Table 1 shows a summary of the radiographical and pathological features of EO in cases reported in the literature.…”

Section: Discussionsupporting

confidence: 73%

See 1 more Smart Citation

A case of epithelioid osteoblastoma of the thoracic vertebra in a 12-year-old male: a case report and review of literature

Zaresharifi,

Karimzadhagh,

Reihanian

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction and importance: Osteoblastoma (OB) is a rare benign bone tumor, representing less than 1% of all bone neoplasms. In contrast to the typical OB, a smaller subset known as “Epithelioid Osteoblastoma (EO)” exhibits a distinctive inclination for local invasion and recurrence. This rare variant can pose diagnostic challenges, particularly due to its unclear clinical and radiological presentation. Case presentation: This study details a clinical case of a 12-year-old boy experiencing pain from a lytic bone tumor located in the thoracic vertebrae (T3-T4), initially suggesting malignancy. Following extensive curettage, histopathological analysis confirmed the diagnosis of Epithelioid Osteoblastoma through immunohistochemical staining. Subsequent follow-up at three months revealed the absence of no pain or recurrence of the lesion. Clinical discussion: Distinguishing EO from a malignant tumor requires a multidisciplinary approach, considering clinical, radiographic, and histological features that differentiate the two entities. Conclusion: The goal of this case presentation is to increase awareness regarding this recurrent tumor variant, which poses diagnostic challenges, particularly in distinguishing it from malignant tumors, including osteosarcoma.

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Section: Discussionsupporting

confidence: 73%

“…OB primarily affects adolescents and young adults, with a mean age of ~20 years. Nevertheless, the more aggressive variants tend to manifest in slightly older patients, with a mean age of around 33 years 3 , 10 , 11 . OBs typically exhibit gradual growth and often remain asymptomatic.…”

Section: Discussionmentioning

confidence: 99%

A case of epithelioid osteoblastoma of the thoracic vertebra in a 12-year-old male: a case report and review of literature

Zaresharifi,

Karimzadhagh,

Reihanian

et al. 2023

Annals of Medicine &Amp; Surgery

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“…Worth noting is that long-lasting tumors produce more sclerosis. Children also display more sclerosis than adults (4,37).…”

Section: Imagingmentioning

confidence: 99%

Osteoid Osteoma: An Updated Review of Epidemiology, Pathogenesis, Clinical Presentation, Radiological Features, and Treatment Option

TEPELENIS

SKANDALAKIS

PAPATHANAKOS

et al. 2021

In Vivo

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Osteoid osteoma, the third most common benign bone tumor, usually occurs in the cortex of long bones. It consists of a radiolucent nidus surrounded by reactive osteosclerosis. Generally, osteoid osteoma affects young males. Nocturnal pain that eases with salicylates or nonsteroidal anti-inflammatory drugs (NSAID) is the typical clinical presentation. Sometimes, it remains undiagnosed for a long time. Plain radiography and computed tomography are usually sufficient for the diagnosis of osteoid osteoma. Initial treatment includes salicylates and NSAID because the tumor often regresses spontaneously over 2-6 years. Surgical treatment is indicated in case of unresponsive pain to medical therapy, no tolerance of prolonged NSAID therapy due to side effects, and no willingness to activity limitations. Nowadays, minimally invasive techniques have replaced open surgery and are considered the gold standard of surgical treatment. Although cryoablation seems superior in terms of the nerve damage and immunotherapy effect, radiofrequency ablation is the preferred technique.

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Osteosarcoma: Case 10

Cheng

Huang

2021

Imaging of Bone Tumors in Shoulder and Elbow

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Benign Osteoid-Producing Bone Lesions: Update on Imaging and Treatment

Cited by 15 publications

References 36 publications

A case of epithelioid osteoblastoma of the thoracic vertebra in a 12-year-old male: a case report and review of literature

A case of epithelioid osteoblastoma of the thoracic vertebra in a 12-year-old male: a case report and review of literature

Osteoid Osteoma: An Updated Review of Epidemiology, Pathogenesis, Clinical Presentation, Radiological Features, and Treatment Option

Osteosarcoma: Case 10

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