Benign opsoclonus in preterm infants

Morad, Yair; Benyamini, Oren G.; Avni, Isaac

doi:10.1016/j.pediatrneurol.2004.03.018

Cited by 17 publications

(19 citation statements)

References 30 publications

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“…41 This report found a significant ocular motility disturbance in 3% of cases. Other reports of specific types of ocular motility disorders include one report of twins with double elevator palsy 52 and another with three cases of benign opsoclonus, 53 which spontaneously resolved. This small number of reports suggests that ocular motility assessment is not an essential component of a screening assessment.…”

Section: Strabismusmentioning

confidence: 99%

Ophthalmological problems associated with preterm birth

O’Connor

Wilson

Fielder

2007

Eye

142

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As survival of preterm infants improves, the long-term care of consequent ophthalmic problems is an expanding field. Preterm birth can inflict a host of challenges on the developing ocular system, resulting in the visual manifestations of varied significance and pathological scope. The ophthalmic condition most commonly associated with preterm birth is retinopathy of prematurity, which has the potential to result in devastating vision loss. However, the visual compromise from increased incidence of refractive errors, strabismus, and cerebral vision impairment has significant impact on visual function, which also has influence on other developmental aspects including psychological and educational. In this review, the normal ocular development is discussed, aiming to exemplify the impact of early exteriorisation on one of the more naive organs of prematurity. This is then related to the incidence and visual consequences of many types of deficit, including refractive error, strabismus, and loss of visual function in preterm populations, with comparisons to term infant studies. Often these conditions are linked with causal and resultant factors being impossible to segregate, but the common factor of increased rates of all types of ophthalmic deficits demonstrates that children born prematurely are indeed premature for life.

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Section: Strabismusmentioning

confidence: 99%

Ophthalmological problems associated with preterm birth

O’Connor

Wilson

Fielder

2007

Eye

142

View full text Add to dashboard Cite

show abstract

“…In our patient, involuntary ocular movement differed from congenital nystagmus, which typically demonstrates horizontal regular amplitude oscillations of the eyes. Half of all OMS cases occur in children with neuroblastoma; therefore, at minimum, abdominal ultrasound is recommended together with urine VMA and HVA, and careful follow up . However, there were no such underlying diseases in our patient.…”

mentioning

confidence: 71%

“…Opsoclonus is characterized by irregular, chaotic, involuntary bursts of high‐amplitude oscillations of the eyes, without pause intervals . Paraneoplastic, parainfectious, metabolic, and toxic etiologies have been commonly reported in patients with opsoclonus or opsoclonus myoclonus syndrome (OMS) . This saccadic eye movement control system may be located in the brainstem and / or cerebellum; previous reports suggest that opsoclonus or OMS may be immune mediated .…”

mentioning

confidence: 99%

“…This saccadic eye movement control system may be located in the brainstem and / or cerebellum; previous reports suggest that opsoclonus or OMS may be immune mediated . In contrast, normal neonates without evidence of abnormal autoimmune response have also been reported . However, the pathophysiology of improvement of opsoclonus remains unclear.…”

mentioning

confidence: 99%

“…Various studies have shown autoimmune abnormalities in opsoclonus . However, opsoclonus has also been reported in healthy neonates . It may therefore occur without autoimmune abnormality, especially due to immaturity of the brain .…”

mentioning

confidence: 99%

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