Benign Multicystic Peritoneal Mesothelioma: A Rare Condition in an Uncommon Gender

Abstract

Benign Multicystic Peritoneal Mesothelioma (BMPM) is a rare condition that arises from the abdominal peritoneum. Fewer than 200 cases have been reported worldwide. BMPM usually affects premenopausal women and is extremely rare in men. Many factors are suspected to contribute to its development, such as previous surgery, endometriosis, and familial Mediterranean fever. The main management is surgical resection; however, it is estimated that the recurrence rate is up to 50%. Malignant transformation is rare. We report a case series of three male patients who were diagnosed with BMPM and were treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC).

Benign Multicystic Peritoneal Mesothelioma in a Male Patient with Previous Wilms’ Tumor: A Case Report and Review of the Literature

“…BMPM was first described in 1928 by Plaut, who incidentally observed some pelvic cystic lesions during surgery for uterine leiomyoma [ 16 ], but its mesothelial nature was identified in 1979 by Mennemeyer and Smith [ 17 ]. To date, less than 200 cases have been reported in literature [ 1 , 2 ].…”

“…This tumor usually affects females of reproductive age, and it is very rare in males [ 1 , 2 , 13 , 15 ]. Our experience is particular because our patient is a young man.…”

“…Its etiopathogenesis is still debated [ 1 , 2 ]. The prevailing theory considers BMPM as the result of a persistent inflammatory status involving the peritoneum because of its association with endometriosis, pelvic inflammatory disease, previous abdominal surgery, and recurrent peritonitis episodes associated with peritoneal dialysis and familial Mediterranean fever [ 3 , 18 , 19 ].…”

“…Physical examination can reveal abdominal distension, abdominal tenderness, and one or more palpable abdominal and/or pelvic masses [ 2 , 15 ]. Our patient presented with a hypogastric mass and diffuse abdominal tenderness without abdominal distension.…”

“…It usually affects females of reproductive age. Its etiopathogenesis is still controversial [ 1 , 2 ]. The prevailing theory considers this tumor as the result of a persistent inflammatory process involving the peritoneum [ 3 ].…”