Benign lymphoid disorders of the lung, with a theory regarding their development

Kradin, Richard L.; Mark, Eugene J.

doi:10.1016/s0046-8177(83)80161-0

Cited by 169 publications

(82 citation statements)

References 43 publications

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“…PNLH was first described by Kradin and Mark as one or more benign nodules or localized lung infiltrates comprised of reactive lymphoid proliferation (1). The concept of localized foci of reactive lymphoid tissue in the lung, termed pseudolymphoma, was initially proposed by Saltzstein (3).…”

Section: Discussionmentioning

confidence: 99%

“…Pulmonary nodular lymphoid hyperplasia (PNLH) is a benign disease with polyclonal lymphoid proliferation (1), indicating a non-tumorous nature. Although the pathological features of PNLH which clarify the entity and related terminology (2) have been summarized, the radiological features of PNLH are not fully recognized, particularly for the cavitary case.…”

Section: Introductionmentioning

confidence: 99%

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A Case of Pulmonary Nodular Lymphoid Hyperplasia with a Resected Cavity, followed by Spontaneous Regression of the Remaining Lesions

et al. 2010

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A 50-year-old man was admitted to our hospital for examination of an abnormal shadow on chest radiography. Computed tomography revealed multiple small nodular shadows in bilateral lung fields, with cavitation in a right S3 lesion that was resected by video-assisted thoracoscopic surgery. Histopathological examination revealed marked proliferation of lymphoid tissue, including many plasma cells that were polyclonal in nature. This case was considered to be pulmonary nodular lymphoid hyperplasia (PNLH). Several residual nodules spontaneously disappeared during the 6 years of follow-up. This was a rare case of PNLH with a resected cavity, followed by spontaneous regression of the remaining lesions.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Case of Pulmonary Nodular Lymphoid Hyperplasia with a Resected Cavity, followed by Spontaneous Regression of the Remaining Lesions

et al. 2010

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“…Its pathological differentiation from mucous associated lymphoid tissue (MALT) lymphoma is important. Previously, this disease was named pseudolymphoma by Salzstein [1][2][3][4]. According to a report by Abbondanzo et al, this disease is mostly detected due to abnormalities on a chest radiograph while the patient is asymptomatic; however, it could also lead to symptoms such as breathing difficulties, coughing (along with production of sputum), pleuritic chest pain, and febricity.…”

Section: Casementioning

confidence: 99%

“…The most vulnerable ages are 50-80 years, and there is no difference in incidence between men and women. Despite there being no known causes, it is speculated to be caused by immune stimulation; it was diagnosed in a patient with Sjögren syndrome, although the association was not verified [1][2][3][4][5][6][7].…”

Section: Casementioning

confidence: 99%

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Multifocal nodular lymphoid hyperplasia of the lung

Lee

Kim

Cho

et al. 2017

Yeungnam Univ J Med

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Nodular lymphoid hyperplasia (NLH) is a benign lymphoproliferative disease that can affect the lung. Because of its rarity, little is known about the etiology and natural history of NLH. Most cases are usually asymptomatic and found incidentally on imaging studies. Imaging finding of NLH has shown most commonly as a solitary lesion, although multifocal pulmonary nodules may be seen. Surgical resection has proved curative in the cases previously described. We report a rare case of NLH in a 55 year-old man who presented with bilateral multiple pulmonary nodules on chest radiography. Open biopsy was performed from the upper and lower lobe of the left lung. The lesions were pathologically diagnosed as pulmonary NLH. Multifocal residual nodules in both lungs remain stable without spontaneous regression during the 3 years of follow-up.

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Pulmonary lymphomas and other pulmonary lymphoid lesions. A clinicopathologic and immunologic study of 64 patients

Kennedy

Nathwani

Burke

et al. 1985

Cancer

133

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Sixty-four patients with lymphoid lesions involving the lung were separated into three groups. In 32 patients, the predominant lymphoid cell population consisted of small, mature-appearing round lymphocytes with or without plasmacytoid features. This group, designated small lymphocytic proliferation (SLP), represents a heterogeneous group of pulmonary lymphocytic lesions including small lymphocytic lymphoma, lymphocytic interstitial pneumonia, and lymphoid hyperplasia (pseudolymphoma). Thirteen S L P patients were identified as having small lymphocytic lymphoma on the basis of monoclonality, progressive disease in other sites, or both. This group was morphologically identical to the remainder of the S L P patients, except for a higher incidence of plasmacytoid features (P = 0.003) and a greater degree of mast cell infiltration (P

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Benign lymphoid disorders of the lung, with a theory regarding their development

Cited by 169 publications

References 43 publications

A Case of Pulmonary Nodular Lymphoid Hyperplasia with a Resected Cavity, followed by Spontaneous Regression of the Remaining Lesions

A Case of Pulmonary Nodular Lymphoid Hyperplasia with a Resected Cavity, followed by Spontaneous Regression of the Remaining Lesions

Multifocal nodular lymphoid hyperplasia of the lung

Pulmonary lymphomas and other pulmonary lymphoid lesions. A clinicopathologic and immunologic study of 64 patients

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