Benign laryngopharyngeal lesions: a case series

Dabholkar, Jyoti; Chhabria, S.; Mishra, Manisha; Chirmade, S.; Sikdar, Abhik

doi:10.1007/s12070-008-0005-1

Cited by 7 publications

(4 citation statements)

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“…Among the 479 articles resulting from our literature search, 60 primary research papers fulfilled our criteria ( Figure 1 ), providing a total of 74 laryngeal schwannoma patients for combined analysis ( Table 1 and Supplemental Tables S1 and S2, available in the online version of the article). 2-61 The included studies consisted primarily of single case reports (n = 55), 4 reports of 2 cases, and 1 larger case series of 11 patients. The mean age at diagnosis was 43.4 years, with women presenting at a later age compared with men (47.3 years vs 32.8, P < .05).…”

Section: Resultsmentioning

confidence: 99%

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Tulli

Bondi

Smart

et al. 2017

Otolaryngol.--head neck surg.

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Objective This review summarizes the clinical features, diagnostic workup, and surgical treatment of laryngeal schwannoma with the aim of providing guidance for the management of this rare disease. The collated data allowed the statistical testing of several hypotheses, including the efficacy of endoscopic vs open surgical intervention and the usefulness of preoperative biopsy. Data Sources PubMed, Google Scholar, Cochrane, and SCOPUS. Review Methods Basic epidemiological and clinical presentation data were collated together with details of diagnostic image modality, lesion attributes, and the use of preoperative biopsy. Surgical approach to intervention and outcome was also collated and simple statistical analyses applied. Results The 60 original articles selected provided a combined cohort of 74 patients for review. The combined data revealed that schwannoma with pedunculated morphology were always safely removed by endoscopic resection regardless of size and should be treated as a separate entity. Of the nonpedunculated schwannoma, larger tumors were more likely to undergo an open approach, which in turn was associated with higher rates of tracheotomy and postoperative vocal fold paralysis. The small cohort did not reveal a significant association between surgery type and persistent disease. Interestingly, the data revealed a significant association between the use of incisional biopsy and persistent disease. Cases exhibiting extralaryngeal extension of the lesion were shown to exclusively belong to patients with neurofibromatosis/schwannomatosis syndromes. Conclusions Taken together, these findings suggest that incisional biopsy should be avoided, and given the benign nature of the pathology, the least invasive radical approach should be employed.

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Section: Resultsmentioning

confidence: 99%

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Tulli

Bondi

Smart

et al. 2017

Otolaryngol.--head neck surg.

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“…Allergy and infective conditions of larynx (as human papilloma virus in respiratory papillomatosis) are also responsible alone or in combination with other factors for the development of such lesions. [2][3][4][5][6][7][8] About 95% of laryngeal carcinomas are typical squamous cell tumors; approximately 40% of patients will have stages III or IV disease when first evaluated. 2,9 Rarely adenocarcinomas are seen to arise from larynx, presumably arising from mucous glands.…”

Section: Introductionmentioning

confidence: 99%

Tumours and tumour like lesions of larynx: a clinicopathological study

Kavitha

Chaitanya

Basavaraju

2018

Int J Otorhinolaryngol Head Neck Surg

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INTRODUCTIONThe human larynx protects the lower respiratory tract, provides a controlled airway, allows phonation and the generation of a high intrathoracic pressure for coughing and lifting. The larynx is divided into the supraglottic, glottis and subglottis based on anatomical location. Tumors of the larynx can be divided into benign or malignant. Laryngeal granulomas, vocal cord nodules, and vocal cord polyps are tumor-like (non-neoplastic) lesions of the larynx. Benign laryngeal tumors include a large number of lesions such as papillomas, hemangiomas, fibromas, chondromas, myxomas, and neurofibromas. The common factors responsible for the development of benign lesions are vocal abuse, misuse, overuse, speaking in unnatural tones, exposure to various irritants like smoke, dust, fumes, alcohol etc. Allergy and infective conditions of larynx (as human papilloma virus in respiratory papillomatosis) are also responsible alone or in combination with other factors for the development of such lesions. [2][3][4][5][6][7][8] About 95% of laryngeal carcinomas are typical squamous cell tumors; approximately 40% of patients will have ABSTRACT Background: Larynx is an important structure in human being forming a part of upper airway and responsible for voice production. Varieties of tumours and tumour like lesions of larynx significantly affect its functions. The aim of the study was to study the clinicopathological aspects of various lesions of larynx. Methods: An observational study was conducted from January 2012 to December 2017 in a tertiary care centre retrospectively. Data collected from departmental registers. History, clinical presentation, relevant investigations and histopathology of biopsy from laryngeal lesions were analysed. Results: The incidence of laryngeal lesions was found to be high between 30-40 years (30.8%) followed by 51-60 years age group (20.9%) with higher preponderance among males (80.25%) compared to females (19.75%). Hoarseness of voice was the commonest presenting symptom in our patients accounting for 80%. It was observed that 27.1% patients were smokers, 10% were addicted to alcohol, and 6% patients had history of both smoking and alcohol consumption. Vocal polyp was the commonest tumour like lesion found in our study (31.4%) followed by vocal nodule (14.1%). Laryngeal papilloma was the only type of benign tumour found in our study (8%) and squamous cell carcinoma of larynx accounts for majority of malignant tumours most of which were moderately differentiated (40%). Conclusions: Majority of the laryngeal lesions are seen among rural population with poor socioeconomic status. Hence, creating awareness about risk factors, symptomatology and better cure with early detection can be life saving.

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“…Allergy and infective conditions of larynx (as human papilloma virus in respiratory papillomatosis) are also responsible alone or in combination with other factors for the development of such lesions. [3][4][5][6][7] First-line treatment for benign lesions is behavioral intervention with speaking and singing therapy. When maximal behavior intervention does not achieve satisfactory improvements in voice, surgical treatment may be considered.…”

Section: Introductionmentioning

confidence: 99%

Pattern of benign lesions of larynx

Prakash¹,

Singh²,

Sharma³

et al. 2016

Int J Med Sci Public Health

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Background: The laryngeal lesions are significant because of the human communication through voice and contribution of voice to the identity of the person. Benign lesions of larynx are classified into the commonly occurring non-neoplastic lesions and relatively rare neoplastic lesions. Objective: To know pattern of benign lesions of larynx. Materials and Methods: This prospective study was conducted in 50 patients who were diagnosed with various benign lesions of larynx during a period of 1 year. After a detailed history, general physical and systemic examination, complete nasal and paranasal examination, and examination of ears, patients were subjected to examination of larynx which included external examination of larynx, indirect laryngoscopy, and microlaryngoscopy under general anesthesia. Result: This prospective study was conducted in 50 patients who were diagnosed with various benign lesions of larynx during a period of 1 year. The incidence was found to be 0.15% or 15 per 10,000 new patients with high prevalence in third, fourth, and fifth decades of life. Non-neoplastic benign lesions were more common (96%) as compared with neoplastic benign lesions (04%) with preponderance in male patients (72%) as compared with female patients (28%). Hoarseness of voice was the most common presenting symptoms seen in 48 to 50 patients. It was observed that 16 patients (32%) were smokers, 5 patients (10%) had exposure to dust, 2 patients (4%) were having incense exposure, and 2 patients (4%) were farmers and had exposure to hay and pollens. Microlaryngoscopic examination under general anesthesia was done in 41 cases. There were 22 cases (44%) of vocal polyps, 16 cases (32%) of vocal nodules, 3 cases (6%) of Reinke's edema, 5 cases (10%) of cysts, and 1 case each of traumatic granuloma, hemangioma, and laryngeal sporidiosis. The predominant site of involvement was the true vocal cords in 44 cases (88%). Simple excision of the lesion was done 36 cases (72%), stripping was done in 3 cases (6%), and endoscopic decapitation and marsupialization was done in 1 case (2%). Conclusion: Benign lesions of larynx are uncommonly occurring lesions. Non-neoplastic benign lesions are far more common than neoplastic lesions, the ratio being 24:1 and most common age group that is involved is 30-40 years. Vocal cord polyps and nodules are the most frequent non-neoplastic benign lesions. Microlaryngeal surgery is the treatment of choice in these lesions and postoperative speech therapy should be provided to all the patients to prevent recurrences.

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Benign laryngopharyngeal lesions: a case series

Cited by 7 publications

References 1 publication

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Tumours and tumour like lesions of larynx: a clinicopathological study

Pattern of benign lesions of larynx

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