Benign intracranial teratoma—Prenatal diagnosis influencing early delivery

Paes, B; Desa, D. J.; Hunter, David J.; Pirani, M

doi:10.1016/0002-9378(82)90558-0

Cited by 19 publications

(4 citation statements)

References 2 publications

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“…In the infant or neonate, these tumours are usually benign (Billmore and Grosfeld, 1986) and can be cured by surgical excision. Over the last decade, teratomas have increasingly been diagnosed by fetal ultrasound and have led to early intervention including neonatal surgery and early delivery (Lipman et al, 1985;Paes et al, 1982;Chervenak et al, 1985). Most teratomas diagnosed by ultrasound have been intracranial or sacrococcygeal.…”

Section: Discussionmentioning

confidence: 99%

In utero development of a mediastinal teratoma: A second‐trimester event

et al. 1994

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Section: Discussionmentioning

confidence: 99%

In utero development of a mediastinal teratoma: A second‐trimester event

et al. 1994

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“…1,2,5,[7][8][9][11][12][13][14] Historically most intracranial teratomas were diagnosed at necropsy, but now they are detected in utero by routine sonography (Table 3). Several forms of congenital intracranial teratoma occur: large tumors replacing the intracranial contents; smaller ones causing hydrocephalus; massive intracranial teratomas with extension into the orbit, oropharynx, or neck; and teratomas presenting as an incidental postmortem finding in a stillborn fetus 6,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28] (Table 3). Because of the size of some tumors, identifiable anatomic landmarks are lost, and therefore in these cases it is not possible to determine the exact site of origin.…”

Section: Teratomamentioning

confidence: 99%

Fetal Brain Tumors: A Review of 154 Cases

Isaacs

2009

Amer J Perinatol

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The purpose of this literature review is to describe the various types of brain tumors that occur in the fetus, their locations, initial findings, pathology, and outcome. Data are presented that show which patients are likely to survive or benefit from treatment compared with those who are unlikely to respond. An analysis is performed on patients with fetal brain tumors that were detected prenatally by imaging studies or discovered directly after birth. The review revealed 154 fetuses presenting with brain tumors. Teratoma was the leading neoplasm. Next was astrocytoma followed by craniopharyngioma, primitive neuroectodermal tumor, choroid plexus papilloma, meningeal tumors, and ependymoma. The most common presenting findings were macrocephaly and an intracranial mass. Overall hydrocephalus was next, followed by stillbirth. Most tumors were detected during the third trimester of pregnancy. Over a third of the affected fetuses were stillborn. Many tumors were inoperable as they occupied much of the intracranial cavity and involved large areas of the brain. Overall survival rate was 23/154, or 15%. Generally fetal brain tumors are associated with a poor prognosis.

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“…Angiography will most commonly show only the presence of an avascular lesion. Ultrasound may help to make the diagnosis of intracranial teratoma in utero [14].…”

Section: Discussionmentioning

confidence: 99%