Benign fibrous histiocytoma of the larynx: presentation of a case and review of the literature

Laer, C. Van; Hamans, Evert; Neetens, I.; Marck, Eric Van; Oosterom, A. Van; Heyning, Paul Van de

doi:10.1017/s0022215100134024

Cited by 12 publications

(4 citation statements)

References 24 publications

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“…Those who died had an average survival of 17 months (range five months to 44 months). All the four patients with benign disease were alive with a survival of nine years, eight years, 38 months and 15 months (Van Laer et al, 1996). Our patient presented eight years ago and is still doing well, currently with no evidence of recurrence in the past 12 months.…”

Section: Discussionmentioning

confidence: 64%

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Fibrous histiocytoma of the larynx

et al. 1998

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We present a case of fibrous histiocytoma of the larynx in a young female who presented eight years ago and is still alive and well with no evidence of any regional invasion or distant metastasis. This rare lesion has been described in 30 cases previously of which 26 were malignant and four benign. Our case is unusual in a sense that histologically it has not been possible to determine its exact biological behaviour and growth potential. However, clinically it behaved as a low-grade malignant tumour.

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Section: Discussionmentioning

confidence: 64%

“…Fibrous histiocytoma of the larynx is a rare disease. To date there have been 30 case reports out of which 26 were reported as malignant and four were benign (Van Laer et al, 1996). Kaufman and Stout first used the term fibrous histiocytoma in 1961.…”

Section: Discussionmentioning

confidence: 99%

Fibrous histiocytoma of the larynx

et al. 1998

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“…Finally, the absence of any large pleiomorphic spindle cells, storiform growth pattern or multinucleated giant cells precluded the diagnosis of fibrous histiocytoma. 10 Following the histopathological analysis, the diagnosis of isolated laryngeal xanthoma was arrived at.…”

Section: Discussionmentioning

confidence: 99%

A rare case of a solitary laryngeal xanthoma and its clinical implications in a developing country like India

Basavarajaiah

Rao

et al. 2021

Int J Otorhinolaryngol Head Neck Surg

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<p class="abstract">We present a rare case of a solitary laryngeal xanthoma in a 42 year old male, with complaints of hoarseness and change in voice since1 year. Direct laryngoscopic examination revealed a smooth textured polyp like mass arising from anterior 1/3rd of left vocal cord. No other similar lesions were noted anywhere else on his body. Microlaryngeal excision of mass was done and sent for histopathological examination, which showed fragments of stratified squamous epithelium with sub-epithelium displaying sheets of foamy cells. Immunohistochemistry was positive for CD68 and a diagnosis of solitary laryngeal xanthoma was arrived at. Follow up of the patient showed no recurrence but investigations revealed dyslipidemia, which was newly detected. Hence a diagnosis of a solitary laryngeal xanthoma, even without any other lesions, warrants a thorough investigative workup, including lipid profile, even in patients who are not known cases of dyslipidemia. This becomes especially important in a country like India, where a large number of cases of dyslipidemia go undetected; leading to atherosclerosis and even cardiac events in the future.</p>

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“…Peripheral ‘reparative’ granuloma (giant cell epulis) is the gingival counterpart of those arising in the jaw bones. Fibrous histiocytomas typically are cutaneous lesions of the extremities but have been reported in the larynx 9 …”

Section: Discussionmentioning

confidence: 99%