Benign Ectopic Thyroid Tissue in the Neck: A Case Report of a Rare Finding

Otondi, Chrispin O; Cason, Frederick D; Kranc, Mark; Waheed, Abdül

doi:10.7759/cureus.7172

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…Ectopic thyroid was mostly due to the aberrant migration and development of normal thyroid gland [ 1 ]. Chrispin argued that the migration of normal thyroid cells after operation may also contribute to the formation of ectopic thyroid [ 2 ]. King et al.…”

Section: Discussionmentioning

confidence: 99%

Bilateral papillary thyroid cancer with normal aberrant thyroid tissue

Huang¹,

Chen

Ma³

2021

Journal of Surgical Case Reports

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Ectopic thyroid tissue, 90% presenting in lingual zone, is often scanned by ultra-sonography or computed tomography. Most surgeons regard ectopic thyroid as metastatic foci from thyroid cancer, thus resection is recommended. Here, we reported a man with bilateral papillary thyroid cancer, accompany with normal ectopic thyroid tissue in right sternocleidomastoid muscle. In this case, we highlighted: (i) It is rarely reported that ectopic normal thyroid tissue presented in sternocleidomastoid muscle. (ii) The ectopic thyroid tissue may not always be metastatic foci even though bilateral thyroid tumors were confirmed to be papillary cancer. (iii) Contrary to radical excision of all ectopic thyroid tissue, we advocate that only patients who need to receive the radioactive iodine therapy after total thyroidectomy should remove the ectopic normal thyroid tissue.

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Section: Discussionmentioning

confidence: 99%

Bilateral papillary thyroid cancer with normal aberrant thyroid tissue

Huang¹,

Chen

Ma³

2021

Journal of Surgical Case Reports

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Benign Intranodal Thyroid Tissue Similar to Nodal Metastasis of Thyroid Papillary Carcinoma: A Rare Case Report

Kang

Cha

2023

Diagnostics

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In patients with thyroid nodules, if the cervical lymph nodes gradually enlarge, a histological confirmation is required to rule out malignancy. Here is a case of benign intranodal thyroid tissue with cystic changes resembling lymph node metastasis of a papillary thyroid carcinoma. A 47-year-old man received ethanol sclerotherapy because of repeated enlargement of the thyroid gland 2 years prior to presentation. Subsequently, the patient underwent abscess removal from the deep neck and partial lobectomy of the attached left thyroid gland. Two months before the visit, extensive cervical lymphadenopathy was detected on ultrasonography (US) and computed tomography (CT). Total thyroidectomy and cervical lymph node dissection were performed to differentiate between metastatic papillary carcinoma of the thyroid gland and benign thyroid inclusions. Microscopic examination revealed multiple variable-sized nodules of benign thyroid follicles with cystic changes in both thyroid glands and bilateral cervical lymph nodes. An occult papillary microcarcinoma strongly positive for HBME-1 was also observed in the left thyroid lobe. However, the benign intranodal thyroid tissue was negative in both the real-time PCR-based BRAF V600E mutation test and HBME-1 immunohistochemical stain. Similarly, benign intranodal thyroid tissue can be enlarged by multiple cystic changes in a large number of lymph nodes along the neck node chain. For the differentiation of metastatic thyroid papillary carcinoma, real-time PCR-based BRAF V600E mutation test and HBME-1 immunohistochemical staining in addition to histological examination are helpful.

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Benign Ectopic Thyroid Tissue in the Neck: A Case Report of a Rare Finding

Cited by 2 publications

References 13 publications

Bilateral papillary thyroid cancer with normal aberrant thyroid tissue

Bilateral papillary thyroid cancer with normal aberrant thyroid tissue

Benign Intranodal Thyroid Tissue Similar to Nodal Metastasis of Thyroid Papillary Carcinoma: A Rare Case Report

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