Benign cardiac tumours, malignant arrhythmias

Myers, K.; Wong, Kenny K.; Tipple, Marion; Sanatani, Shubhayan

doi:10.1016/s0828-282x(10)70009-x

Cited by 33 publications

(46 citation statements)

References 12 publications

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“…Direct myocardial invasion may result in dysrhythmias, valvular insufficiency, dynamic outflow tract obstruction, congestive heart failure, and cardiac tamponade. 3,4 Vascular obstruction may lead to superior vena cava syndrome, hepatic congestion, ascites, and lower extremity edema. [1][2][3]5 Respiratory symptoms, such as cough, stridor, or wheezing may occur secondary to external tracheobronchial compression.…”

Section: Discussionmentioning

confidence: 99%

“…As with our patient, primary cardiac tumours are a substrate for generation of malignant arrhythmia, which may be medically refractory and increase the risk of sudden cardiac death. 4 Antiarrhythmic medications and defibrillation should be readily available. 4 Preload augmentation is essential to mitigate dynamic outflow tract obstruction or tamponade.…”

Section: Discussionmentioning

confidence: 99%

“…4 Antiarrhythmic medications and defibrillation should be readily available. 4 Preload augmentation is essential to mitigate dynamic outflow tract obstruction or tamponade. Chronotropic agents should be used judiciously as these may be arrhythmogenic and may potentially worsen dynamic outflow tract obstruction.…”

Section: Discussionmentioning

confidence: 99%

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Case report: Giant cardiac malignancy in a nine-year-old female

Scott

Troshynski

Clarke

et al. 2012

Can J Anesth/J Can Anesth

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Purpose To describe the management of a giant cardiac malignancy initially diagnosed as an anterior mediastinal mass. Clinical features A nine-year-old female with right facial swelling and chronic cough was diagnosed with a large right mediastinal mass. Intermittent ventricular and supraventricular arrhythmias were noted on admission electrocardiograms. Empiric corticosteroid and radiation therapy did not reduce the size of the tumour, and initial tissue biopsies were non-diagnostic. Due to worsening tamponade physiology and persistent arrhythmias, the patient was scheduled for tumour debulking with potential resection. Prior to surgery, a multidisciplinary team was assembled to delineate team member responsibilities and treatment algorithms. The procedure was performed under general anesthesia with spontaneous ventilation preserved during endotracheal intubation and invasive line placement. The team was prepared to provide extracorporeal mechanical support if needed. The child required inotropic and vasoactive medications after transitioning to positive pressure ventilation, but her hemodynamics improved with sternotomy. The lesion was identified as a malignant cardiac clear-cell tumour that was unresectable. Her sternum was left open, as attempted closure led to the re-creation of tamponade physiology. She underwent delayed sternal closure days later. After months of chemotherapy that resulted in significant tumour involution, she underwent successful surgical resection. Conclusion Giant primary cardiac tumours may present similarly to large anterior mediastinal masses. The care of patients with these lesions requires an understanding of the risks associated with mediastinal masses as well as those unique to cardiac tumours. A multidisciplinary approach is critical to providing safe and effective care throughout this process. RésuméObjectif De´crire la prise en charge d'une tumeur cardiaque ge´ante initialement diagnostique´e comme e´tant une masse me´diastinale ante´rieure. Caractéristiques cliniques Un diagnostic de volumineuse masse me´diastinale droite a e´te´fait chez une fillette aˆge´e de neuf ans, pre´sentant une enflure de la partie droite du visage

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Case report: Giant cardiac malignancy in a nine-year-old female

Scott

Troshynski

Clarke

et al. 2012

Can J Anesth/J Can Anesth

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“…9,10 Monomorphic ventricular tachycardia is one of the most frequently reported types of cardiac metastasis-related ventricular arrhythmia in both children and adults. [11][12][13][14] In contrast, polymorphic ventricular tachycardia (PMVT) in the setting of cardiac metastasis has been reported only once. 15 We describe an adult patient who presented with sustained PMVT as a manifestation of metastatic melanoma, and review the manifestations and consequences of cardiac involvement of melanoma.…”

Section: Introductionmentioning

confidence: 99%

An Uncommon Presentation for Cardiac Melanoma

Baykalır¹,

Young²,

Slosky³

et al. 2014

Journal of Patient-Centered Research and Reviews

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Journal of Patient-Centered Research and Reviews ( JPCRR) is a peerreviewed scientific journal whose mission is to communicate clinical and bench research findings, with the goal of improving the quality of human health, the care of the individual patient, and the care of populations. Recommended Citation An Uncommon Presentation for Cardiac Melanoma AbstractA 66-year-old man with locally advanced malignant melanoma, which was surgically resected, presented with a 3-week history of dizziness, recurrent near-syncopal episodes and generalized weakness. He was found to have sustained polymorphic ventricular tachycardia in the setting of cardiac melanoma. We draw attention to an unusual presentation of malignant melanoma with cardiac metastasis and discuss both its etiology and treatment options. (J Patient-Centered Res Rev. 2014;1:128-132.)

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“…A large tumor may determine a compression of cardiac chambers or vital structures, leading to arrhythmias and obstruction of cardiac valves and subsequent obstruction of the tracts. 5 The objective of this study was to analyze the clinical and echocardiographic features of cardiac tumors in the neonatal period.…”

mentioning

confidence: 99%