Benign and non-neoplastic tumours of the duodenum

Latos, Wojciech; Kawczyk‐Krupka, Aleksandra; Strzelczyk, Natalia; Sieroń, Aleksander; Cieślar, Grzegorz

doi:10.5114/pg.2019.90250

Cited by 4 publications

(3 citation statements)

References 46 publications

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“…Since gastrointestinal GTs are rare, preoperative diagnosis is difficult. The differential diagnosis may include GIST, leiomyoma, neuroendocrine tumor (NET), lymphoma, ectopic pancreas, hemangioma, and secondary metastasis [ 13 ]. In our case, we preoperatively diagnosed GIST or leiomyoma.…”

Section: Discussionmentioning

confidence: 99%

Glomus tumor of the duodenum: a rare case report

et al. 2020

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Background Glomus tumors (GTs) are mesenchymal neoplastic lesions arising from the glomus bodies and generally occur in the fingers and toes. Gastrointestinal GTs are rare, and most of them originate from the stomach; however, GT arising from the duodenum is exceedingly rare. Case presentation A 68-year-old man was admitted due to abdominal pain. Endoscopy showed a round, smooth, elevated mass in the second portion of the duodenum with central ulceration. Abdominal contrast computed tomography showed a hypervascular tumor measuring 26 mm in diameter in the second portion of the duodenum, and pancreatic invasion was suspected. Endoscopic ultrasonography of the lesion confirmed a hypoechoic mass arising from the fourth layer of the duodenal wall. A biopsy was performed for central ulceration, and immunochemical studies showed positive results for smooth muscle actin (SMA) and negative results for S100, C-Kit, and CD34. Leiomyoma or gastrointestinal stromal tumor was suspected and pancreatoduodenectomy was performed. The specimen exhibited a vascular-rich tumor, 24 × 24 × 19 mm in size, with deep ulceration in the duodenum. Histological examination showed uniform small round cells with central nuclei and a pale cytoplasm (glomus cell) with perivascular proliferation. Immunochemical studies showed that the tumor was positive for SMA and collagen type IV, and negative for C-Kit, CD34, desmin, and S100. We diagnosed the tumor as a GT of the duodenum. Conclusion GTs of the duodenum are exceedingly rare, but should be considered in the differential diagnoses of duodenal submucosal lesions.

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Section: Discussionmentioning

confidence: 99%

Glomus tumor of the duodenum: a rare case report

et al. 2020

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“…Over 60% of small intestinal tumors are found in the duodenum, and the most frequent malignancies of the duodenum include GISTs, neuroendocrine neoplasm, adenocarcinoma, lymphoma, sarcoma, teratoma, and secondary metastases [2]. GISTs is the most common submucosal tumours of gastrointestinal tract, which originate from connective tissue, muscle, lymphoid tissue, adipose tissue, nerves and blood vessels located below the submucosa [7]. GISTs can be probably classi ed as unfavourable prognosis when they are more than 5 cm, occuring tumor rupture and the mitotic rate is more than 5 mitoses per 50 high-power elds [8].…”

Section: Discussionmentioning

confidence: 99%

Endoscopic submucosal dissection for treatment of stromal tumor of descending duodenum in association with postoperative perforation and retroperitoneal abscess: a case report

Wei¹,

Gong²,

Huang³

et al. 2020

Preprint

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Background: With the development of endoscopic technology, the clinical detection rates of duodenal lesions have been significantly increased. Endoscopic submucosal dissection (ESD) has been increasingly applied to the minimally invasive treatment of duodenal space-occupying lesions and has similar therapeutic effects as surgery. However, postoperative complications such as perforation and bleeding easily occur after ESD, but there were few reports about it. We report a case, which we designed to evaluate the efficacy and safety of ESD treatment for stromal tumor in descending duodenum. Case presentation: A 64-year-old woman suffered from duodenal fistula and retroperitoneal abscess after ESD for stromal tumor in descending duodenum. The purse-string suture therapy of the wound was not very effective for the patient during the operation. Thus, the patient underwent a series of treatment measures successfully, such as endoscopic jejunum feeding tube placement, anti-infection, endoscopic closure of duodenal fistula, etc, and without evidence of perforation of duodenum. Follow-up was done for 6 months without recurrence. Conclusions: ESD is a efficient and promising strategy for treating of stromal tumor in descending duodenum, while the ESD of security needs to be further evaluated.

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“…Researchers have proposed algorithms that increase the effectiveness of detecting abnormal tissue, especially dysplastic and neoplastic, but also inflammed tissue in pulmonology, gastrology, and urology [ 24 , 25 ]. High-fluorescence fields are interlaced with low-fluorescence areas that are close to normal, or clearly lower, and correlated with the NCV index [ 26 , 27 , 28 , 29 ].…”

Section: Methodsmentioning

confidence: 99%

Photodynamic Therapy for the Treatment of Infected Leg Ulcers—A Pilot Study

et al. 2021

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Chronic and infected leg ulcers (LUs) are painful, debilitating, resistant to antibiotics, and immensely reduce a patient’s quality of life. The purpose of our study was to demonstrate the efficacy of photodynamic therapy (PDT) for the treatment of infected chronic LUs. Patients were randomized into two experimental groups: the first group received 5-aminolevulinic acid photodynamic therapy (ALA-PDT) (10 patients), and the second group of 10 patients received local octenidine dihydrochloride (Octenilin gel) exposed to a placebo light source with an inserted filter that mimiced red light. In the PDT group, we used 20% ALA topically applied for 4 hrs and irradiation from a Diomed laser source with a wavelength of 630 nm at a fluency of 80 J/cm2. ALA-PDT was performed 10 times during a 14-day hospitalization in 10 patients of both sexes aged 40–85 years with chronic leg ulcers. Treatments were carried out at 3-week intervals for 3–5 cycles. At 8-month follow-up with the PDT group, complete remission (CR) was obtained in four patients (40%), partial response (>50% reduction in ulcer diameter) in four patients (40%), and no response in two patients (20%) who additionally developed deterioration of the local condition with swelling, erythema, and inflammation. To assess the degree of pain during the trials, we used a numeric rating scale (NRS). From the preliminary results obtained, we concluded that PDT can be used to treat leg ulcers as a minimally invasive and effective method with no serious side effects, although further studies on a larger group of patients with LUs are warranted.

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Benign and non-neoplastic tumours of the duodenum

Cited by 4 publications

References 46 publications

Glomus tumor of the duodenum: a rare case report

Glomus tumor of the duodenum: a rare case report

Endoscopic submucosal dissection for treatment of stromal tumor of descending duodenum in association with postoperative perforation and retroperitoneal abscess: a case report

Photodynamic Therapy for the Treatment of Infected Leg Ulcers—A Pilot Study

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