Benign and Malignant Lesions of the Spleen

Enlargement of the spleen as an incidental finding on CT in post-partum females with fever

“…Findings that could explain the fever were present in the majority of patients after Caesarean section and in approximately one-third of the patients after vaginal delivery. None of these findings were associated with splenomegaly, and none of the patients had any evidence of infection, such as endocarditis, acquired immune deficiency syndrome, haematological disease or other conditions that could account for the splenomegaly [7][8][9][10]. (a) (b) Enlargement of the spleen is associated with several abnormal conditions, such as haematological disorders, infectious diseases, hepatic diseases and storage diseases, in order of decreasing incidence [7][8][9][10].…”

“…None of these findings were associated with splenomegaly, and none of the patients had any evidence of infection, such as endocarditis, acquired immune deficiency syndrome, haematological disease or other conditions that could account for the splenomegaly [7][8][9][10]. (a) (b) Enlargement of the spleen is associated with several abnormal conditions, such as haematological disorders, infectious diseases, hepatic diseases and storage diseases, in order of decreasing incidence [7][8][9][10]. Therefore, if an enlarged spleen is detected in an otherwise healthy patient, this finding might initiate a systematic work-up, which could be costly, time consuming and worrying for the patient.…”

Management of splenic “incidentalomas” found on ultrasound and computed tomography

“…Metastases and lymphoma are the two most common splenic malignancies, and although both are very rarely seen in the setting of an incidental finding. There are only a few dozen reports of isolated splenic metastases in the literature, so incidental splenic lesions without any evidence of metastases elsewhere are unlikely to be metastatic [ 3 ]. Similarly, most splenic lymphomas are seen in patients with systemic disease, and evidence of lymphoma can be found elsewhere on the scan.…”