Benign and highly efficient synthesis of quinolines from 2-aminoarylketone or 2-aminoarylaldehyde and carbonyl compounds mediated by hydrochloric acid in water

1,1′-{1,4-Phenylene bis[3-(6-chloro-2-methyl-4-phenylquinolin-3-yl)-4,5-dihydro-1H-pyrazole-5,1-diyl]}dibutan-1-one

“…3-Acetyl-6-chloro-2-methyl-4-phenylquinoline (1) has been synthesized in accordance with established methods [14]. Spectroscopic results and physical properties are in agreement with literature reports [15,16].…”

A Novel Enzymatic Synthesis of Quinoline Derivatives

“…The results were summarized in Table 3. Few reports of cyclopentanone derivatives [13,[24][25][26][27] have been reported. Thus we tried some cyclopentanone substrates.…”

“…[5][6][7][8] Traditional synthetic routes usually have poor yields, long reaction times, and harsh conditions. Therefore, new methods for constructing quinoline derivatives are constantly sought [9][10][11][12][13][14][15][16][17].…”

Silica-based sulfonic acid (MCM-41-SO3H): a practical and efficient catalyst for the synthesis of highly substituted quinolines under solvent-free conditions at ambient temperature

“…Reports showed that acid catalysts are more effective than base catalysts for this reaction. There has been some development for the synthesis of quinolines derivatives using acid catalysts such as p-toluenesulfonic acid 11 , hydrochloric acid 12,13 , . But, many of these procedures have been highlight led to suffer from various problems such as low yields, harsh reaction conditions, difficulties in workup, expensive reagents, long reaction times, and the use of toxic solvents.…”