Benefits of Bariatric Surgery Do Not Reach Obese Men

Fuchs, Hans; Broderick, Ryan C.; Harnsberger, Cristina R.; Chang, David C.; Sandler, Bryan J.; Jacobsen, Garth R.; Horgan, Santiago

doi:10.1089/lap.2014.0639

Cited by 107 publications

(50 citation statements)

References 27 publications

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“…Although the representation of males in the current study appears low, it is comparable to other studies conducted in this clinic [43, 44]. In general, males tend to be underrepresented in obesity treatment studies [45, 46]. Additionally, we were unable to explore definitions of sarcopenia using a measure of muscle function, as these were not collected as part of patient's initial assessment.…”

Section: Discussionmentioning

confidence: 67%

Prevalence of Sarcopenic Obesity in Adults with Class II/III Obesity Using Different Diagnostic Criteria

Johnson-Stoklossa

Sharma

Forhan

et al. 2017

Journal of Nutrition and Metabolism

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Background/Objective. Sarcopenic obesity (SO) is a hidden condition of reduced lean soft tissue (LST) in context of excess adiposity. SO is most commonly reported in older adults and both its risk and prevalence increase with age. A variety of body composition indices and cut points have been used to define this condition, leading to conflicting prevalence and risk prediction. Here, we investigate variability in the prevalence of SO in an adult sample of individuals with class II/III obesity (BMI ≥ 35 kg/m2) using different diagnostic criteria. Methods. SO definitions were identified from a literature review of studies using dual-energy X-ray absorptiometry (DXA) to assess LST. Demographics, anthropometrics, and body composition (by DXA) were measured in n = 120, 86% female (46.9 ± 11.1 years). Results. LST was extremely variable in individuals, even with similar body sizes, and observed across the age spectrum. The prevalence of SO ranged from 0 to 84.5% in females and 0 to 100% in males, depending upon the definition applied, with higher prevalence among definitions accounting for measures of body size or fat mass. Conclusion. SO is present, yet variable, in adults with class II/III obesity. Accounting for body mass or fat mass may identify a higher number of individuals with SO, although risk prediction remains to be studied.

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Section: Discussionmentioning

confidence: 67%

Prevalence of Sarcopenic Obesity in Adults with Class II/III Obesity Using Different Diagnostic Criteria

Johnson-Stoklossa

Sharma

Forhan

et al. 2017

Journal of Nutrition and Metabolism

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“…Similar to the findings of our case series, the majority of reported cases were women, tended to be middle aged and were mostly diagnosed years after the bariatric procedure, and the majority had Roux‐en‐Y gastric bypass. The increased proportion of women is likely because more bariatric surgeries are done in women than men . In this case series, we also report patients who developed UC after bariatric surgery as well as a minority of cases of IBD following bariatric procedures other than Roux‐en‐Y, specifically gastric band and sleeve gastrectomy.…”

Section: Discussionmentioning

confidence: 81%

Bariatric surgery is associated with increased risk of new‐onset inflammatory bowel disease: case series and national database study

Ungaro

Fausel

Chang

et al. 2018

Aliment Pharmacol Ther

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“…Finally, it must be noticed that our study only included females participants. We focused on females as there is a well-documented disparity in the number of females versus men seeking bariatric surgery, with percentages ranging from 70–80% versus 20–30% 49, 50 . However, gender differences have been reported in brain functional connectivity 51 , specifically in the PCC 52 and in the default mode network connectivity 53 , though this finding is not constant 54 .…”

Section: Discussionmentioning

confidence: 99%

Resting-state brain connectivity changes in obese women after Roux-en-Y gastric bypass surgery: A longitudinal study

Olivo

Zhou

Sundbom

et al. 2017

Sci Rep

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Bariatric surgery is an effective method to rapidly induce weight loss in severely obese people, however its impact on brain functional connectivity after longer periods of follow-up is yet to be assessed. We investigated changes in connectivity in 16 severely obese women one month before, one month after and one year after Roux-en-Y gastric bypass surgery (RYGB). 12 lean controls were also enrolled. Resting-state fMRI was acquired for all participants following an overnight fast and after a 260 kcal load. Connectivity between regions involved in food-related saliency attribution and reward-driven eating behavior was stronger in presurgery patients compared to controls, but progressively weakened after follow-up. At one year, changes in networks related to cognitive control over eating and bodily perception also occurred. Connectivity between regions involved in emotional control and social cognition had a temporary reduction early after treatment but had increased again after one year of follow-up. Furthermore, we could predict the BMI loss by presurgery connectivity in areas linked to emotional control and social interaction. RYGBP seems to reshape brain functional connectivity, early affecting cognitive control over eating, and these changes could be an important part of the therapeutic effect of bariatric surgery.

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Benefits of Bariatric Surgery Do Not Reach Obese Men

Cited by 107 publications

References 27 publications

Prevalence of Sarcopenic Obesity in Adults with Class II/III Obesity Using Different Diagnostic Criteria

Prevalence of Sarcopenic Obesity in Adults with Class II/III Obesity Using Different Diagnostic Criteria

Bariatric surgery is associated with increased risk of new‐onset inflammatory bowel disease: case series and national database study

Resting-state brain connectivity changes in obese women after Roux-en-Y gastric bypass surgery: A longitudinal study

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