Benefits of a Repetitive Facilitative Exercise Program for the Upper Paretic Extremity After Subacute Stroke

Shimodozono, Megumi; Noma, Tomokazu; Nomoto, Yoshiko; Hisamatsu, Noriaki; Kamada, Katsuya; Miyata, Ryuji; Matsumoto, Shûji; Ogata, Atsuko; Etoh, Seiji; Basford, Jeffrey R.; Kawahira, Kazumi

doi:10.1177/1545968312465896

Cited by 78 publications

(43 citation statements)

References 45 publications

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“…Despite clinical and technological advances over recent decades in the understanding and treatment of ischemic stroke, these dysfunctions significantly reduce the quality of daily life for patients [2,3,4]. However, recent rodent studies have indicated that physical exercise acts as an effective rehabilitation program for treatment of ischemic stroke [5,6] by promoting the recovery of the sensory-motor function and preventing deterioration in cognitive ability [7]. Similarly, Lee et al ., have reported that moderate activity can protect against brain injury after a stroke [8].…”

Section: Introductionmentioning

confidence: 99%

Physical Exercise Promotes Recovery of Neurological Function after Ischemic Stroke in Rats

Zheng

Zhang

Luo

et al. 2014

IJMS

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Although physical exercise is an effective strategy for treatment of ischemic stroke, the underlying protective mechanisms are still not well understood. It has been recently demonstrated that neural progenitor cells play a vital role in the recovery of neurological function (NF) through differentiation into mature neurons. In the current study, we observed that physical exercise significantly reduced the infarct size and improved damaged neural functional recovery after an ischemic stroke. Furthermore, we found that the treatment not only exhibited a significant increase in the number of neural progenitor cells and neurons but also decreased the apoptotic cells in the peri-infarct region, compared to a control in the absence of exercise. Importantly, the insulin-like growth factor-1 (IGF-1)/Akt signaling pathway was dramatically activated in the peri-infarct region of rats after physical exercise training. Therefore, our findings suggest that physical exercise directly influences the NF recovery process by increasing neural progenitor cell count via activation of the IGF-1/Akt signaling pathway.

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Section: Introductionmentioning

confidence: 99%

Physical Exercise Promotes Recovery of Neurological Function after Ischemic Stroke in Rats

Zheng

Zhang

Luo

et al. 2014

IJMS

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“…"Repetitive Facilitation Exercise" (RFE or Kawahira Method) is an effective rehabilitation method that can manifest the brain plasticity [5] [6] [7] [8]. However, there are problems that procedure lore of effective techniques such as RFE is difficult.…”

Section: A Need For Training Aid Device In Hemiplegic Rehabilitationmentioning

confidence: 99%

Research of training and evaluation aid device with DOF selective constraint mechanism for hemiplegic upper limbs rehabilitation

Taniguchi

Noma

et al. 2015

2015 IEEE International Conference on Mechatronics (ICM)

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As sequelae of stroke, hemiplegia is a typical symptom, where paralysis occurs in the half the body because of brain damage. In this study, we have developed selectable constraint mechanism for hemiplegic upper limb training. By using this mechanism, it became possible to separate synergic movement while flexion-extension training of shoulder and elbow by constraining each individual joints. As the clinical trial result, the shoulder-elbow UE-FMA sub-scores improved significantly. In addition, we proposed NMES timing control system and evaluation method for sensing the flexion-extension movement of the elbow and shoulder joints.

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“…"Repetitive Facilitation Exercise" (RFE or Kawahira Method) is an effective rehabilitation method that can potentially manifest the brain plasticity [3] ∼ [6]. This method involves inducing the stretch reflex of the human body through training, and it achieves intended movements of the patient by increasing the facilitating effect by triggering active voluntary movements.…”

Section: Introductionmentioning

confidence: 99%

Development of rehabilitation device for hemiplegic fingers by finger-expansion facilitation exercise with stretch reflex

Iwashita

Kawahira

et al. 2013

2013 IEEE International Conference on Robotics and Biomimetics (ROBIO)

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This paper develops a motor function recovery exercise device to perform intensive repetition of facilitation exercise for motor functional recovery of the hemiplegic fingers. On the facilitation exercise, active finger expansion can be realized and facilitated by stretch reflex. When the figer is being flexed passively, a stimulation tapping is applied instantaneously on the finger for making strech reflex and active finger expansion. Then, resistance forces are applied on the expanding finger for maintaining the strech reflex. In this paper, novel parallel mechanisms, force sensing system with high sensitivity and resistance accompanying cooperation control method are proposed for sensing, controlling and realizing the passive finger flexion, stimulation tapping, stretch reflex, active finger expansion, resistance forces and repetition facilitation exercise. The effectivities and performances of the device are shown by some experiments.

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Benefits of a Repetitive Facilitative Exercise Program for the Upper Paretic Extremity After Subacute Stroke

Abstract: These findings suggest that RFE may be more effective than conventional rehabilitation in lessening impairment and improving upper-limb motor function during the subacute phase of stroke.

Cited by 78 publications

References 45 publications

Physical Exercise Promotes Recovery of Neurological Function after Ischemic Stroke in Rats

Physical Exercise Promotes Recovery of Neurological Function after Ischemic Stroke in Rats

Research of training and evaluation aid device with DOF selective constraint mechanism for hemiplegic upper limbs rehabilitation

Development of rehabilitation device for hemiplegic fingers by finger-expansion facilitation exercise with stretch reflex

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