Benefits of a prolonged-release amino acid mixture in four pregnant women with phenylketonuria
Simona Sestito,
Lucia Brodosi,
Stefania Ferraro
et al.
Abstract:Background: Maternal phenylketonuria (mPKU) is a pathologic condition occurring in the fetus of a mother with PKU that is caused by prolonged elevated intrauterine blood phenylalanine (Phe) levels, which can lead to congenital abnormalities and mental retardation of newborns. Management of PKU during pregnancy can be challenging as protein substitutes may exacerbate nausea, vomiting, and gastrointestinal symptoms. Aim: To report the successful management of four PKU pregnant women. Methods: The patients were a… Show more
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