Benefits in Nutritional Interventions in Patients With CKD Stage 3-4

Chauveau, P.; Aparicio, Michel

doi:10.1053/j.jrn.2010.11.005

Cited by 15 publications

(18 citation statements)

References 14 publications

(7 reference statements)

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“…However, convincing evidence indicates that reduced protein intake favorably affects disease progression in patients with stage 3-4 CKD and delays the time to renal death (28). Reduced blood urea levels and proteinuria in CKD patients on low-and very low-protein diets delay kidney function decline; however, a close monitoring of these patients including supplementation of certain nutrients is required.…”

Section: A Protein-rich Diet and Impaired Kidney Functionmentioning

confidence: 99%

The Western-style diet: a major risk factor for impaired kidney function and chronic kidney disease

Odermatt

2011

American Journal of Physiology-Renal Physiology

215

128

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The Western-style diet is characterized by its highly processed and refined foods and high contents of sugars, salt, and fat and protein from red meat. It has been recognized as the major contributor to metabolic disturbances and the development of obesity-related diseases including type 2 diabetes, hypertension, and cardiovascular disease. Also, the Western-style diet has been associated with an increased incidence of chronic kidney disease (CKD). A combination of dietary factors contributes to the impairment of renal vascularization, steatosis and inflammation, hypertension, and impaired renal hormonal regulation. This review addresses recent progress in the understanding of the association of the Western-style diet with the induction of dyslipidemia, oxidative stress, inflammation, and disturbances of corticosteroid regulation in the development of CKD. Future research needs to distinguish between acute and chronic effects of diets with high contents of sugars, salt, and fat and protein from red meat, and to uncover the contribution of each component. Improved therapeutic interventions should consider potentially altered drug metabolism and pharmacokinetics and be combined with lifestyle changes. A clinical assessment of the long-term risks of whole-body disturbances is strongly recommended to reduce metabolic complications and cardiovascular risk in kidney donors and patients with CKD.

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Section: A Protein-rich Diet and Impaired Kidney Functionmentioning

confidence: 99%

The Western-style diet: a major risk factor for impaired kidney function and chronic kidney disease

Odermatt

2011

American Journal of Physiology-Renal Physiology

215

128

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“…Meanwhile, the results of epidemiological studies conducted for recent years have convincingly demonstrated that nutritional status disorders appear to be revealed much earlier, before dialysis treatment starting, from stages 3B-4 CKD, and impact on prognosis of patients on dialysis [1,2,12,13,15]. The incidence of PEW depends on the stage of CKD ( Table 1): among CKD patients with a glomerular filtration rate (GFR) of 44-30 ml/min/1.73m 2 , PEW is detected in 4.2% of cases in average, whereas in CKD patients with GFR of 29-15 ml/min/1.73m 2 in 21.3%, and almost all patients with end-stage of CKD have PEW [1,2,7,13,15,16].…”

Section: Prevalence Pew In Ckdmentioning

confidence: 99%

“…In contrast to the end products of fat and carbohydrate metabolism (CO 2 and H 2 O) that are excreted through the lungs and skin, the products of protein metabolism can be excreted only by kidneys [7,16].…”

Section: Etiology and Pathogenesismentioning

confidence: 99%

“…LPD, reducing glomerular hypertension, favors decreasing proteinuria as well as hemodynamic damage of renal glomeruli and thus contributing to a slowdown of CKD progression [2,6,7]. The influence of LPD on CKD progression is more expressed in case of diabetic nephropathy (DN).…”

Section: Introductionmentioning

confidence: 99%

“…The influence of LPD on CKD progression is more expressed in case of diabetic nephropathy (DN). The annual rate of glomerular filtration rate (GFR) decline in patients who follow LPD and slow down by 1.5-2 times compared with standard diet, and outcome to the end-stage of CKD is observed less often almost by three times [5,7]. Renal protective effects of LPD are connected with its hemodynamic and metabolic abilities.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Nutritional Status Disorders in Chronic Kidney Disease: Practical Aspects (Systematic Review)

Milоvаnоvа¹,

Fоmin²,

Lysenko³

et al. 2018

Chronic Kidney Disease - From Pathophysiology to Clinical Improvements

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Despite the significant achievements in the management of chronic kidney disease (CKD) patients, the mortality rate of these patients still remains high. Nutritional status disorders (NSD) are considered now as one of the prognostic risk factors not only for dialysis but also for predialysis CKD stages. Since the publication of KDIGO 2012 guidelines for CKD patient's management, there has been some significant advancement in our understanding of main NSD mechanisms in CKD, including different nosological group patients (first, in diabetic and systemic diseases patients). At the same time, there is still an urgent need for randomized trials for better-informed decisions and future optimization of CKD patients' care. This chapter provides the current data on all aspects of NSD in CKD: etiology, diagnosis, prevention, and treatment approaches, as well as on risk factors of NSD at predialysis stages and in chronic hemodialysis patients. Considerable attention was devoted to the diagnosis and differential diagnosis of NSD in CKD patients. It was determined that the overall strategy for dietary treatment contributed to improving the life quality of patients and slowing down of CKD progression. The review is written based on the published results of clinical studies performed on the position of evidencebased medicine.

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Protein restriction for diabetic kidney disease

Jiang

Fang

2021

Cochrane Database of Systematic Reviews

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Benefits in Nutritional Interventions in Patients With CKD Stage 3-4

Cited by 15 publications

References 14 publications

The Western-style diet: a major risk factor for impaired kidney function and chronic kidney disease

The Western-style diet: a major risk factor for impaired kidney function and chronic kidney disease

Nutritional Status Disorders in Chronic Kidney Disease: Practical Aspects (Systematic Review)

Protein restriction for diabetic kidney disease

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