“…They stimulate terminal myogenic differentiation and fusion of MuSCs via the secretion of factors (IGF‐1, TGF‐β, GDF3…) (Arnold et al, 2007 ; Lu et al, 2011 ; Saclier et al, 2013 ; Varga, Mounier, Patsalos, et al, 2016 ). Restorative macrophages also promote angiogenesis, they stimulate fibroblastic cells for extracellular matrix (ECM) remodeling and secrete themselves ECM components (e.g., proteoglycans, matricellular proteins and assembly proteins) (Varga, Mounier, Horvath, et al, 2016 , for reviews see Panci & Chazaud, 2021 ; Singh & Chazaud, 2021 ). The kinetics of the inflammatory response is fundamental for the good orchestration of myogenesis and the surrounding supportive biological processes.…”