Benefit-Risk Analysis for Foods (BRAFO)- Executive Project Summary

Vidry, Stéphane; Hoekstra, Jeljer; Hart, Andy; Watzl, Bernhard; Verhagen, Hans; Schütte, Katrin; Boobis, Alan R.; Chiodini, Alessandro

doi:10.9734/ejnfs/2013/7007

Cited by 11 publications

(17 citation statements)

References 5 publications

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“…Results from this research may aid further qualitative and quantitative risk–benefit assessments of coffee consumption, using published approaches (Hoekstra and others ; Verhagen and others ; Boobis and others ; Vidry and others ; Hart and others ) and further activities emphasizing the potential benefits should be pursued. As such, the potential benefits for public health of consuming coffee or not consuming coffee could be calculated for the most convincing benefits (for example, type 2 diabetes and neurological and/or hepatic disorders).…”

Section: Future Workmentioning

confidence: 89%

A Comprehensive Overview of the Risks and Benefits of Coffee Consumption

Pourshahidi

Navarini

Petracco

et al. 2016

Comp Rev Food Sci Food Safe

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Findings on both the health benefits and the potentially harmful effects of coffee consumption have been contradictory. However, the general scientific consensus is that moderate, regular coffee drinking by healthy individuals is either essentially benign or mildly beneficial. Results and generalizations are complicated by a number of factors, including differences in age, gender, health status, type of coffee preparation, serving size, and source of coffee. Coffee may have potential health benefits and risks, but causality cannot be established for either with the research currently available as these are largely based on observational data. This review aimed to provide a comprehensive overview of the risks and benefits of coffee consumption on health outcomes. A systematic search (search terms: "coffee" OR "coffee adj3" [consum * or intake * or drink * ]) of the literature (from 1970; humans; in English) using the electronic databases "OVID," "CINAHL," and "Web of Knowledge" returned 12405 results. Duplicates were removed, studies were screened (based on inclusion/exclusion criteria), and the remaining eligible studies (n = 1277) were used to collate an exhaustive list of the potential health benefits and risks of coffee consumption, which were grouped and are discussed with regard to major diseases/conditions (mortality, cardiovascular disease, cancer, and metabolic/liver/neurological disorders), atrisk/vulnerable groups, and specific coffee constituents. This qualitative assessment has shown that the health benefits (or null effects) clearly outweigh the risks of moderate coffee consumption in adult consumers for the majority of health outcomes considered. Results from this research may aid further qualitative and quantitative deterministic risk-benefit assessments of coffee consumption.

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Section: Future Workmentioning

confidence: 89%

A Comprehensive Overview of the Risks and Benefits of Coffee Consumption

Pourshahidi

Navarini

Petracco

et al. 2016

Comp Rev Food Sci Food Safe

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“…The interplay between HBGVs from the perspective of toxicological risk assessment and from the perspective of nutrition have been considered before in many papers, such as, but not limited to, Renwick et al (2004), Verkaik-Kloosterman et al (2012), Bruins et al (2015; EFSA, 2006;NASEM (2018). Moreover, HBGVs for micronutrients have been the underlying considerations for integrated risk-benefit assessment for food and nutrition (Tijhuis et al, 2012a(Tijhuis et al, , 2012bBoobis et al, 2013;Vidry et al, 2013). A detailed review of the different approaches proposed is outside the scope of this Statement.…”

Section: Interpretation Of the Terms Of Referencementioning

confidence: 99%

“…(2015); EFSA, 2006; NASEM (2018). Moreover, HBGVs for micronutrients have been the underlying considerations for integrated risk‐benefit assessment for food and nutrition (Tijhuis et al., 2012a, 2012b; Boobis et al., 2013; Vidry et al., 2013). A detailed review of the different approaches proposed is outside the scope of this Statement.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Statement on the derivation of Health‐Based Guidance Values (HBGVs) for regulated products that are also nutrients

More¹,

Bampidis²,

Benford³

et al. 2021

EFS2

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This Statement presents a proposal for harmonising the establishment of Health-Based Guidance Values (HBGVs) for regulated products that are also nutrients. This is a recurrent issue for food additives and pesticides, and may occasionally occur for other regulated products. The Statement describes the specific considerations that should be followed for establishing the HBGVs during the assessment of a regulated product that is also a nutrient. It also addresses the elements to be considered in the intake assessment; and proposes a decision tree for ensuring a harmonised process for the risk characterisation of regulated products that are also nutrients. The Scientific Committee recommends the involvement of the relevant EFSA Panels and units, in order to ensure an integrated and harmonised approach for the hazard and risk characterisation of regulated products that are also nutrients, considering the intake from all relevant sources.

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“…Devos et al., ; Url, ). As discussions become framed more broadly, a more holistic approach to assessing and addressing risks has been suggested, where risks are weighed against benefits (Tijhuis et al., ; Boobis et al., ; Vidry et al., ; Boué et al., ). It has also been suggested that decisions should be made about the acceptability of new technologies in the context of other risks as well as the costs of not using these technologies (Tait and Barker, ).…”

Section: Fit‐for‐purpose Food Safety Risk Assessmentmentioning

confidence: 99%

Conducting fit‐for‐purpose food safety risk assessments

Devos

Elliott

Macdonald

et al. 2019

EFS2

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The interplay between science, risk assessment and risk management has always been complex, and even more so in a world increasingly characterised by rapid technical innovation, new modes of communication, suspicion about authorities and experts, and demands for people to have a say in decisions that are made on their behalf. In this challenging era where scientific advice on food safety has never been in greater demand, risk managers should effectively navigate the interplay between facts and values and be able to rely on robust and fit-for-purpose risk assessments to aid them. The fact that societal resistance is often encountered when scientific advice on food safety operates at a distance from social values and fails to actively engage with citizens, has led to increasing emphasis on the need to advance forms of risk assessment that are more contextual, and socially sound and accountable. EFSA's third Scientific Conference explored how risk assessments could be constructed to most usefully meet society's needs and thus connect science with society, while remaining scientifically robust. Contributors to the conference highlighted the need to: (1) frame risk assessments by clear policy goals and decision-making criteria; (2) begin risk assessments with an explicit problem formulation to identify relevant information; (3) make use of reliable risk assessment studies; (4) be explicit about value judgements; (5) address and communicate scientific uncertainty; (6) follow trustworthy processes; (7) publish the evidence and data, and report the way in which they are used in a transparent manner; (8) ensure effective communication throughout the risk analysis process; (9) involve society, as appropriate; and (10) weigh risks and benefits on request. Implementation of these recommendations would contribute to increased credibility and trustworthiness of food safety risk assessments.

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Benefit-Risk Analysis for Foods (BRAFO)- Executive Project Summary

Abstract: This study has been carried out with partial financial support by the Commission of the European Communities, and was coordinated by ILSI Europe.

Cited by 11 publications

References 5 publications

A Comprehensive Overview of the Risks and Benefits of Coffee Consumption

A Comprehensive Overview of the Risks and Benefits of Coffee Consumption

Statement on the derivation of Health‐Based Guidance Values (HBGVs) for regulated products that are also nutrients

Conducting fit‐for‐purpose food safety risk assessments

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