Benefit of F-15 protocols in equivocal F + 20 MAG3 renography in children with upper tract dilatation and symmetric split function: Results and outcomes

Diuretic Renal Scintigraphy: The State of Practice and a Potential Opportunity for Standardization

“…Such studies compared the F-15, Fþ0, and Fþ20 protocols, primarily assessing the number of equivocal examination results and the number of interrupted studies due to patients moving or needing to void before study completion. Researchers found that the Fþ20 protocol led to a higher percent of equivocal TACs in regard to determining the presence or absence of obstruction in addition to an inherent longer study time [11,[15][16][17]. The F-15 and Fþ0 protocols both demonstrated fewer equivocal curves and more definitive results.…”

Management of ureteropelvic junction obstruction in children—a roundtable discussion

“…YPUC: Different protocols exist for the timing of diuretic administration. A recent publication describes a F-15 protocol for use in cases with repeated equivocal MAG3 scans [12]. It is also important to bear in mind that a randomized trial comparing primary F-15 versus Fþ20 protocols cautioned that there was a seven times increased chance of diagnosing obstruction with F-15 protocol, raising the risk of false-positive results [13].…”

The Preparation of 99mTc-MAG3 radiotracer by Ultrasound

“…The 99m Tc-MAG 3 clearance is correlated with the effective renal plasma flow (ERPF). Finally, the administered dose of 99m Tc-MAG 3 is less than 99m Tc-DTPA in dynamic renal scintigraphy and consequently, the radiation dose to patients especially pediatrics and staff could be reduced [9][10][11][12][13][14] . The radiolabeling of 99m Tc-DTPA is simply reconstituted by adding a sterile eluted solution of 99m TcO 4 to the freeze-dried kit in accordance with the manufacturer's product specification at the room temperature.…”