Beneficial effects of training at the anaerobic threshold in addition to pharmacotherapy on weight loss, body composition, and exercise performance in women with obesity

Abstract

ObjectiveThe aim of this study was to determine and compare the effects of weight loss achieved through orlistat therapy alone or a combination of orlistat and an aerobic exercise training program on aerobic fitness and body composition in obese females.MethodsTwenty-eight obese patients were randomly assigned to receive 12-week treatment with hypocaloric diet–orlistat or diet–orlistat–exercise. Each participant performed an incremental ramp exercise test every 4 weeks to measure aerobic fitness. Fourteen participants performed continuous exercise (approximately 45 minutes per session) at a work rate corresponding to the anaerobic threshold three times per week.ResultsA decrease in the fat mass to body weight ratio of 3.8% (P=0.006) was observed at the end of the 12 weeks in the orlistat group, while a decrease of 9.5% (P=0.001) was seen in the orlistat–exercise group. Maximal exercise capacity increased by 46.5% in the orlistat–exercise group and by 19.5% in the orlistat group.ConclusionWhile orlistat therapy resulted in an improvement in body composition and aerobic fitness at the end of the 12-week period, its combination with exercise training provided improvements in the same parameters within the first 4 weeks of the study. These additional beneficial effects of combining aerobic exercise with orlistat therapy are important with regards to obesity-associated risk factors.

Evaluating of altered hydration status on effectiveness of body composition analysis using bioelectric impedance analysis

“…It has been revealed that BIA is a useful, easily applicable, and inexpensive tool for the evaluation of body composition of obese [10], cardiometabolic disorders [1][2][3][4], cancer [8], and hemodialysis patients [18]. Obtaining confidential information with regarding specific proportion of each section of body composition (TBW, FFM, %FM and FM) in health and also some disorder is a continue interest of clinical and scientist.…”

“…Approximately in the last five years, it has been suggested that body composition could be assessed by measuring resistance to electrical activity from different parts of the body [7]. This method has been termed as bioelectrical impedance analysis (BIA) and widely used for evaluation of body compartments in many clinical and non-clinical situations [8][9][10]. BIA is considered to be easily, noninvasively, quickly applied non-invasive method and provide reliable outcome in research and clinical trials.…”

Comparative Evaluation of MDA Levels During Aerobic Exercise in Young Trained and Sedentary Male Subjects

“…Regular physical activity and exercise studies have a major importance in the treatment, rehabilitation and prevention of various diseases including cardiac, metabolic, and respiratory systems (1,3,4). However, despite the beneficial effects on health, acute exercise may also cause an increased oxidative stress in the body (5).…”

Effects of morning and nocturnal soccer matches on levels of some trace elements in young trained males

“…Exercise is an effective stimulatory factor on energy metabolic systems (4). In addition acute exercise may cause a significant increase in levels of oxidative stress in body (5,6).…”