Beneficial effects of seaweeds and seaweed-derived bioactive compounds: Current evidence and future prospective

Pradhan, Biswajita; Bhuyan, Prajna Paramita; Patra, Srimanta; Nayak, Rabindra; Behera, Pradyota Kumar; Behera, Chhandashree; Behera, Akshaya Kumar; Ki, Jang‐Seu; Jena, Mrutyunjay

doi:10.1016/j.bcab.2021.102242

Cited by 64 publications

(16 citation statements)

References 54 publications

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“…The fresh and marine ecosystems are rich in biodiversity and hold a potential source of sulfated polysaccharides ( Behera et al, 2020 ; Behera et al, 2021 ; Dash et al, 2020 ; Dash et al, 2021 ; Maharana et al, 2019 ; Pradhan, Maharana, Bhakta, & Jena, 2021 ; Pradhan, Patra, Behera, et al, 2020 ; Pradhan, Patra, Dash, et al, 2021 ). Algae-derived sulfated polysaccharides such as fucoidan have potentially been used as an antiviral agent ( Pagarete et al, 2021 ; Pradhan, Bhuyan, et al, 2022 ; Pradhan, Nayak, et al, 2022 ; Pradhan, Patra, Nayak, et al, 2020 ). Many marine algae species contain large amounts of complicated structural sulphated polysaccharides that have been demonstrated to impede enveloped virus replication ( Pereira & Critchley, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

A state-of-the-art review on fucoidan as an antiviral agent to combat viral infections

Pradhan

Nayak

Patra

et al. 2022

Carbohydrate Polymers

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Section: Introductionmentioning

confidence: 99%

A state-of-the-art review on fucoidan as an antiviral agent to combat viral infections

Pradhan

Nayak

Patra

et al. 2022

Carbohydrate Polymers

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“…Searching of natural compounds in disease various prevention is most promising [114][115][116][117][118][119][120][121]. In this regard, phytoplankton are gaining much attention [122].…”

Section: Phytoplankton Toxin and Their Disease Preventing Activitiesmentioning

confidence: 99%

Toxic Effects and Tumor Promotion Activity of Marine Phytoplankton Toxins: A Review

Pradhan

Kim

Abassi

et al. 2022

Toxins

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Phytoplankton are photosynthetic microorganisms in aquatic environments that produce many bioactive substances. However, some of them are toxic to aquatic organisms via filter-feeding and are even poisonous to humans through the food chain. Human poisoning from these substances and their serious long-term consequences have resulted in several health threats, including cancer, skin disorders, and other diseases, which have been frequently documented. Seafood poisoning disorders triggered by phytoplankton toxins include paralytic shellfish poisoning (PSP), neurotoxic shellfish poisoning (NSP), amnesic shellfish poisoning (ASP), diarrheic shellfish poisoning (DSP), ciguatera fish poisoning (CFP), and azaspiracid shellfish poisoning (AZP). Accordingly, identifying harmful shellfish poisoning and toxin-producing species and their detrimental effects is urgently required. Although the harmful effects of these toxins are well documented, their possible modes of action are insufficiently understood in terms of clinical symptoms. In this review, we summarize the current state of knowledge regarding phytoplankton toxins and their detrimental consequences, including tumor-promoting activity. The structure, source, and clinical symptoms caused by these toxins, as well as their molecular mechanisms of action on voltage-gated ion channels, are briefly discussed. Moreover, the possible stress-associated reactive oxygen species (ROS)-related modes of action are summarized. Finally, we describe the toxic effects of phytoplankton toxins and discuss future research in the field of stress-associated ROS-related toxicity. Moreover, these toxins can also be used in different pharmacological prospects and can be established as a potent pharmacophore in the near future.

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“…Synthetic antibiotics are frequently used to treat microbial diseases in humans but they often exert several side effects, such as renal dysfunction and cardiovascular diseases [1,2]. Therefore, the search for natural compounds in preventing various diseases is very promising [3][4][5][6][7][8][9][10][11][12]. The treatment of infectious bacterial diseases is even more critical if the patient suffers from concomitant pathologies, such as tuberculosis, pneumonia, salmonellosis, and gonorrhea, often leading to the patient's death [13].…”

Section: Introductionmentioning

confidence: 99%

Algal Phlorotannins as Novel Antibacterial Agents with Reference to the Antioxidant Modulation: Current Advances and Future Directions

et al. 2022

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The increasing drug resistance of infectious microorganisms is considered a primary concern of global health care. The screening and identification of natural compounds with antibacterial properties have gained immense popularity in recent times. It has previously been shown that several bioactive compounds derived from marine algae exhibit antibacterial activity. Similarly, polyphenolic compounds are generally known to possess promising antibacterial capacity, among other capacities. Phlorotannins (PTs), an important group of algae-derived polyphenolic compounds, have been considered potent antibacterial agents both as single drug entities and in combination with commercially available antibacterial drugs. In this context, this article reviews the antibacterial properties of polyphenols in brown algae, with particular reference to PTs. Cell death through various molecular modes of action and the specific inhibition of biofilm formation by PTs were the key discussion of this review. The synergy between drugs was also discussed in light of the potential use of PTs as adjuvants in the pharmacological antibacterial treatment.

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Beneficial effects of seaweeds and seaweed-derived bioactive compounds: Current evidence and future prospective

Cited by 64 publications

References 54 publications

A state-of-the-art review on fucoidan as an antiviral agent to combat viral infections

A state-of-the-art review on fucoidan as an antiviral agent to combat viral infections

Toxic Effects and Tumor Promotion Activity of Marine Phytoplankton Toxins: A Review

Algal Phlorotannins as Novel Antibacterial Agents with Reference to the Antioxidant Modulation: Current Advances and Future Directions

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