Beneficial effects of banding on venous intimal-medial hyperplasia in arteriovenous loop grafts

Fillinger, Mark F.; Reinitz, Emanuel R.; Schwartz, Robert A.; Resetarits, Dennis E.; Paskanik, Andrew M.; Bredenberg, Carl E.

doi:10.1016/0002-9610(89)90353-x

Cited by 81 publications

(47 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[10][11][12][13][14] The results presented above suggest that forming an AVF via a vein graft onto a straight artery, or onto the inner-curvature of a curved artery, will result in unsteady blood flow patterns and WSS distributions within both the artery (50-60 Hz) and potentially (depending on the venous diameter) within the vein (up to 650 Hz). However, forming an AVF via a vein graft onto the outer-curvature of a curved artery can suppress such unsteadiness.…”

Section: Summary and Biological Implicationsmentioning

confidence: 99%

“…In particular regions of low Wall Shear Stress (WSS), highly oscillatory flow, and low Lumen-to-Wall Oxygen Flux (LWOF), leading to wall hypoxia, are all implicated in the initiation of IH. [5][6][7][8][9][10][11][12][13][14][15][16][17] There have been various computational studies of blood flow within AVF and Arterio-Venous Grafts (AVG). In 2003, Loth et al 18 simulated blood flow within idealized AVG and compared results with those obtained in vivo.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Computational modelling of the interaction of shock waves with multiple gas-filled bubbles in a liquid

Betney

Tully²,

Hawker³

et al. 2015

Physics of Fluids

View full text Add to dashboard Cite

This study presents a computational investigation of the interactions of a single shock wave with multiple gas-filled bubbles in a liquid medium. This work illustrates how multiple bubbles may be used in shock-bubble interactions to intensify the process on a local level. A high resolution front-tracking approach is used, which enables explicit tracking of the gas-liquid interface. The collapse of two identical bubbles, one placed behind the other is investigated in detail, demonstrating that peak pressures in a two bubble arrangement can exceed those seen in single bubble collapse. Additionally, a parametric investigation into the effect of bubble separation is presented. It is found that the separation distance has a significant effect on both the shape and velocity of the main transverse jet of the second bubble. Extending this analysis to effects of relative bubble size, we show that if the first bubble is sufficiently small relative to the second, it may become entirely entrained in the second bubble main transverse jet. In contrast, if the first bubble is substantially larger than the second, it may offer it significant protection from the incident shock. This protection is utilised in the study of a triangular array of three bubbles, with the central bubble being significantly smaller than the outer bubbles. It is demonstrated that, through shielding of bubbles until later in the collapse process, pressures over five times higher than the maximum pressure observed in the single bubble case may be achieved. This corresponds to a peak pressure that is approximately 40 times more intense than the incident shock wave. This work has applications in a number of different fields, including cavitation erosion, explosives, targeted drug delivery/intensification, and shock wave lithotripsy.

show abstract

Section: Summary and Biological Implicationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Computational modelling of the interaction of shock waves with multiple gas-filled bubbles in a liquid

Betney

Tully²,

Hawker³

et al. 2015

Physics of Fluids

View full text Add to dashboard Cite

show abstract

Section: Summary and Biological Implicationsmentioning

confidence: 99%

Section: -2 Iori Et Almentioning

confidence: 99%

The effect of in-plane arterial curvature on blood flow and oxygen transport in arterio-venous fistulae

et al. 2015

View full text Add to dashboard Cite

Arterio-Venous Fistulae (AVF) are the preferred method of vascular access for patients with end stage renal disease who need hemodialysis. In this study, simulations of blood flow and oxygen transport were undertaken in various idealized AVF configurations. The objective of the study was to understand how arterial curvature affects blood flow and oxygen transport patterns within AVF, with a focus on how curvature alters metrics known to correlate with vascular pathology such as Intimal Hyperplasia (IH). If one subscribes to the hypothesis that unsteady flow causes IH within AVF, then the results suggest that in order to avoid IH, AVF should be formed via a vein graft onto the outer-curvature of a curved artery. However, if one subscribes to the hypothesis that low wall shear stress and/or low lumen-to-wall oxygen flux (leading to wall hypoxia) cause IH within AVF, then the results suggest that in order to avoid IH, AVF should be formed via a vein graft onto a straight artery, or the inner-curvature of a curved artery. We note that the recommendations are incompatible—highlighting the importance of ascertaining the exact mechanisms underlying development of IH in AVF. Nonetheless, the results clearly illustrate the important role played by arterial curvature in determining AVF hemodynamics, which to our knowledge has been overlooked in all previous studies.

show abstract

“…Hemodialysis is one of the treatment choices for these patients and arteriovenous shunt (AVS) is vital for hemodialysis therapy, because it makes a surgical connection between an arterial anastomosis site and a venous anastomosis site. AVS occlusion and failure causes turbulent flow, high wall shear stress, and high blood pressure [3]. In clinical examinations, for visualization of the vascular access, using angiography is the gold standard for the diagnosis of stenosis [4].…”

Section: Introductionmentioning

confidence: 99%

Arteriovenous Shunt Stenosis Evaluation Using a Fractional-Order Fuzzy Petri Net Based Screening System for Long-Term Hemodialysis Patients

Chen¹,

Kan²,

Lin³

2014

JBiSE

View full text Add to dashboard Cite

This paper proposes the evaluation of arteriovenous shunt (AVS) stenosis using a fractional-order Fuzzy Petri net based screening system for long-term hemodialysis treatment of patients. The screening system uses the Burg method, the fractional-order chaos system, and the Fuzzy Petri net (FPN) for early detection of AVS dysfunction. The Burg method is an autoregressive (AR) model that is used to estimate the frequency spectra of a phonoangiographic signal and to identify the spectral peaks in the region from 25 Hz to 800 Hz. In AVS, the frequency spectrum varies between normal blood flow and turbulent flow. The power spectra demonstrate changes in frequency and amplitude as the degree of stenosis changes. A screening system combining fractional-order chaos system and FPN is used to track the differences in the frequency spectra between the normal and stenosis access. The dynamic errors are indexes that can be used to evaluate the degree of AVS stenosis using a FPN. For 42 long-term follow-up patients, testing results show that the proposed screening system is more efficient in the evaluation of AVS stenosis.

show abstract

Beneficial effects of banding on venous intimal-medial hyperplasia in arteriovenous loop grafts

Cited by 81 publications

References 11 publications

Computational modelling of the interaction of shock waves with multiple gas-filled bubbles in a liquid

Computational modelling of the interaction of shock waves with multiple gas-filled bubbles in a liquid

The effect of in-plane arterial curvature on blood flow and oxygen transport in arterio-venous fistulae

Arteriovenous Shunt Stenosis Evaluation Using a Fractional-Order Fuzzy Petri Net Based Screening System for Long-Term Hemodialysis Patients

Contact Info

Product

Resources

About