Beneficial effects of a cardiac support device on left ventricular remodeling after posterior myocardial infarction: an evaluation by echocardiography, pressure–volume curves and ventricular histology

Okada, Miyako; Akita, Toshiaki; Mizuno, Fumito; Nakayama, Asami; Morioka, Kouichi

doi:10.1007/s00595-015-1202-7

Cited by 4 publications

(5 citation statements)

References 19 publications

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“…Thus, the second limitation of this study was that we did not consider the native coronary arterial flow, graft diameter, and hemodynamics. Myocardial infarction was reported to cause ventricular remodeling and deterioration of ventricular function [13]. As myocardial viability and ventricular remodeling may influence the microvascular resistance, further study on the influence of blood flow on native coronary arteries or myocardial microvascular resistance is required.…”

Section: Discussionmentioning

confidence: 99%

Quantitative assessment technique of HyperEye medical system angiography for coronary artery bypass grafting

et al. 2016

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Section: Discussionmentioning

confidence: 99%

Quantitative assessment technique of HyperEye medical system angiography for coronary artery bypass grafting

et al. 2016

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“…To achieve PM re-alignment without any intracardiac surgery, several groups have engineered innovative devices that could restore LV geometry and the inter-PM distance by external compression of the inferior LV wall. They showed that PM re-approximation using balloon patches, myocardial wrapping in mesh material, or highly fine-tuned external cardiac support devices without SMA successfully restored MV coaptation and even contributed to reverse LV remodeling, thus, long-term prevention of recurrent IMR after inferior MI (see Figure 11) [111,112,[117][118][119][120][121][122][123][124]. Some devices have made it to first-in-man application and the technologies are expected to further evolve and become available in a more wide-spread fashion.…”

Section: Implications For Existing and Future Surgical And Interventi...mentioning

confidence: 99%

Utilization of Engineering Advances for Detailed Biomechanical Characterization of the Mitral–Ventricular Relationship to Optimize Repair Strategies: A Comprehensive Review

et al. 2023

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The geometrical details and biomechanical relationships of the mitral valve–left ventricular apparatus are very complex and have posed as an area of research interest for decades. These characteristics play a major role in identifying and perfecting the optimal approaches to treat diseases of this system when the restoration of biomechanical and mechano-biological conditions becomes the main target. Over the years, engineering approaches have helped to revolutionize the field in this regard. Furthermore, advanced modelling modalities have contributed greatly to the development of novel devices and less invasive strategies. This article provides an overview and narrative of the evolution of mitral valve therapy with special focus on two diseases frequently encountered by cardiac surgeons and interventional cardiologists: ischemic and degenerative mitral regurgitation.

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“…29 Furthermore, the metal sheet-type electrodes form fibrous connective tissue around them that substantially increases the DFT. Recently, a Heart correction net that is attached to the outside of the heart has been proposed as a device for treating heart failure, 30,31 and the manufacturing technologies for tailor-made cardiac devices that fit the shape of individual hearts has been already established. 32 The idea of using the heart support net with a linear electrode conductor as a defibrillator has already been proposed.…”

Section: Translational Perspectivementioning

confidence: 99%

Low‐energy defibrillation using a base–apex epicardial electrode

Okada,

Washio,

Sugiura

et al. 2023

Pacing Clinical Electrophis

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BackgroundCurrent implantable cardioverter defibrillators (ICDs) require electric conduction with high voltage and high energy, which can impair cardiac function and induce another malignant arrhythmia. As a result, there has been a demand for an ICD that can effectively operate with lower energy to mitigate the risks of a strong electric shock.MethodsA pair of sheet‐shaped electrodes covering the heart were analyzed in three configurations (top–bottom, left–right, and front–back) using a heart simulator. We also varied the distance between the two electrodes (clearance) to identify the electrode shape with the lowest defibrillation threshold (DFT). We also investigated the ICD shock waveform, shock direction, and the effect of the backside insulator of the electrode.ResultsThe DFT was high when the clearance was too small and the DFT was high even when the clearance was too large, suggesting that an optimal value clearance. The top–bottom electrodes with optimal clearance showed the lowest DFT when the biphasic shocks set the top electrode to a high potential first and then the bottom electrode was set to a high potential. An interval between a first shock waveform and a second shock waveform should be provided for low‐energy defibrillation. Because the insulator prevents unnecessary current flow to the backside, the DFT of the electrodes with insulators is less than those without insulators.ConclusionPainless defibrillation using sheet‐shaped electrodes on the epicardium is predicated on the basis of results using a heart simulator.

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Beneficial effects of a cardiac support device on left ventricular remodeling after posterior myocardial infarction: an evaluation by echocardiography, pressure–volume curves and ventricular histology

Abstract: Early application of a CSD after posterior MI can attenuate LV remodeling without causing any deterioration of the biventricular diastolic function.

Cited by 4 publications

References 19 publications

Quantitative assessment technique of HyperEye medical system angiography for coronary artery bypass grafting

Quantitative assessment technique of HyperEye medical system angiography for coronary artery bypass grafting

Utilization of Engineering Advances for Detailed Biomechanical Characterization of the Mitral–Ventricular Relationship to Optimize Repair Strategies: A Comprehensive Review

Low‐energy defibrillation using a base–apex epicardial electrode

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