Beneficial Effect of Flecainide Controlled Release on the Quality of Life of Patients with Atrial Fibrillation—the REFLEC-CR Study

Tzeis, Stylianos; Tsiachris, Dimitriοs; Asvestas, Dimitrios; Kourouklis, Spiridon; Patsourakos, Fotios; Karlis, Dimitrios; Kouskos, G.P.; Papadimitriou, George; Gavriilidou, Marianna; Vatkalis, Nikolaos; Kapetanios, Konstantinos; Koufaki, Panagiota; Taxiarchou, Efstathios; Giannakoulas, George; investigators, Reflec-Cr study

doi:10.1007/s10557-020-06971-5

Cited by 2 publications

(1 citation statement)

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“…In the series by Tzeis et al which enrolled 680 patients in 70 centres in Greece, the administration of flecaine to patients for rhythm maintenance showed an improvement in quality of life irrespective of the dosage of the molecule (100mg or 200mg) [18]. Although other antiarrhythmic drugs such as cordarone or calcium channel blockers have been used in some patients in the same series, a comparative study of their impact on quality of life parameters has not been performed.…”

Section: Discussionmentioning

confidence: 99%

Impact of Return to Sinus Rhythm on Quality of Life in Patients with Atrial Fibrillation

et al. 2022

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Improving quality of life in AF is a clinical issue in the management of this disease. The choice of therapeutic strategy; rhythm or rate control would influence the parameters of quality of life assessment. The aim of our study was to describe the impact of maintaining sinus rhythm after cardioversion on the quality of life of patients followed for AF.To do this we conducted a prospective descriptive study including 24 patients followed for paroxysmal, persistent and prolonged persistent AF. Quality of life was assessed by two scores (AFEQT, SF-36) validated for atrial fibrillation. The average age of our population was 53.3 years. Half of our sample had no underlying heart disease. We observed an improvement in quality of life in patients who maintained sinus rhythm. A contradictory result was observed in patients who had a recurrence of the arrhythmia. We also found that age, treatments and comorbidities influenced the quality of life of patients followed for AF. The results found in our study are consistent with the literature; the differences found are probably related to the size of our random sample and the number of scales used to assess quality of life. The use of quality of life scores could be a key issue for the follow-up of these patients in order to integrate a global management approach.

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Section: Discussionmentioning

confidence: 99%