Beneficial effect of autologous blood transfusion on infectious complications after colorectal cancer surgery

Heiss, M. M.; Kw, Jauch; Delanoff, Christian; Mayer, G; Schildberg, F. W.; Mempel, W; Mempel, M.; Eissner, H-J.

doi:10.1016/0140-6736(93)92247-q

Cited by 377 publications

(268 citation statements)

References 24 publications

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“…Other studies corroborate these findings [28,29]. Chlorhexidine gluconate-containing products require several applications to attain maximum antimicrobial benefit, so repeated antiseptic showers are usually indicated [30].…”

Section: Preoperative Issues Preoperative Antiseptic Showeringsupporting

confidence: 70%

Surgical Site Infections in Relation to the Timing of Shaving among the Gastrointestinal Emergency Patients through the Midline Incisions- A Randomized Controlled Clinical Trial

Hossain¹

2012

J Med Microb Diagn

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Section: Preoperative Issues Preoperative Antiseptic Showeringsupporting

confidence: 70%

Surgical Site Infections in Relation to the Timing of Shaving among the Gastrointestinal Emergency Patients through the Midline Incisions- A Randomized Controlled Clinical Trial

Hossain¹

2012

J Med Microb Diagn

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“…33 Surgical patients receiving allogeneic transfusions develop impaired cellular immunity [34][35][36][37][38] associated with increases in postoperative bacterial infections, [39][40][41][42] cancer recurrence, 43,44 multiorgan failure, [45][46][47][48][49][50] and poorer wound healing. [51][52][53] Could ABO nonidentical transfusions cause impaired cellular immune function, infection, and multiorgan failure, but by a different mechanism than that causing hemolysis?…”

Section: Transfusion Studiesmentioning

confidence: 99%

What would Karl Landsteiner do? The ABO blood group and stem cell transplantation

Heal

Liesveld

Phillips

et al. 2005

Bone Marrow Transplant

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Summary:ABO blood group antigens, of great importance in transplantation and transfusion, are present on virtually all cells, as well as in soluble form in plasma and body fluids. Naturally occurring plasma IgM and IgG antibodies against these antigens are ubiquitous. Nonetheless, the ABO blood group system is widely ignored by many transfusion services, except for purposes of red cell transfusion. We implemented a policy of transfusing only ABO identical platelets and red cells in patients undergoing stem cell transplantation or treatment for hematologic malignancies. Major bleeding episodes have occurred in about 5% of patients undergoing induction therapy for acute leukemia as compared with 15-20% in the literature. Overall survival times appear to be superior to that in historical cohorts. In 2002-2004, treatment-related mortality at 100 days in our Blood and Marrow Transplant Unit was 0.7% for autologous transplants (n ¼ 148), 13% for sibling allogeneic transplants (n ¼ 110), and 24% (n ¼ 62) for matched unrelated allogeneic transplants, suggesting that our approach is safe. We speculate that more rigorous efforts on the part of transfusion services to provide ABO identical blood components, and to remove incompatible supernatant plasma, when necessary, might yield reduced morbidity and mortality in patients undergoing stem cell transplantation. Bone Marrow Transplantation (2005) 36, 747-755.

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“…Avoiding allogeneic blood transfusions has become an important issue in the peri-operative care of surgical patients [1][2][3]. Besides transmission of infectious diseases, transfusion reactions and other side-effects such as immunosuppression induced by allogeneic blood transfusions is of particular relevance for surgical patients because this may result in an increased incidence of postoperative infectious complications [2,10,11]. Therefore, the American Society of Anesthesiologists Task Force on Blood Component Therapy recently recommended careful adherence to proper indications for blood and blood component therapy [3].…”

Section: R Spahn Et Al • Haemodilution Tolerancementioning

confidence: 99%

Haemodilution tolerance in patients with mitral regurgitation

et al. 1998

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SummaryHaemodynamic parameters and oxygen consumption were determined in 20 patients with mitral regurgitation before and after a 12 ml.kg ¹1 isovolaemic exchange of blood for 6% hydroxyethyl starch. During haemodilution, mean (SEM) haemoglobin concentration decreased from 13.0 (0.4) to 10.3 (0.4) The avoidance of blood transfusion is an important issue in the care of surgical patients. Haemodilution and acceptance of minimal haemoglobin values in the peri-operative period are becoming increasingly advocated [1][2][3]. Although tolerance to moderate haemodilution has been shown in patients with coronary artery disease [4], there is no information available on how patients with mitral regurgitation respond to haemodilution [2]. In addition, there are no data on the haemodilution tolerance of patients whose heart rhythm is atrial fibrillation. MethodsWith ethics committee approval and after written informed consent, 20 patients with mitral regurgitation scheduled for first-time mitral valve surgery were enrolled into the study. Exclusion criteria included a history of coronary artery disease, concomitant mitral valve stenosis, aortic valve pathology and a haemoglobin less than 10 g.dl ¹1 . Patients were premedicated with flunitrazepam 1-2 mg orally Ϸ 2 h before induction of anaesthesia. In the anaesthesia induction area, patients were monitored with a pulse oximeter and a five-lead ECG. A peripheral venous cannula and a radial arterial catheter were inserted. Patients were preloaded with 5 ml.kg ¹1 Ringer's lactate solution. Anaesthesia was then induced with fentanyl (4-10 mg.kg ¹1 ) and midazolam (50-150 mg.kg ¹1 ). Pancuronium (0.12 mg.kg ¹1 ) was given to provide muscle relaxation. During induction of anaesthesia, additional Ringer's lactate solution was given to treat a decrease in blood pressure with concomitant low cardiac filling pressures or marked respiratory variation in the arterial pulse pressure. Anaesthesia was maintained with fentanyl (0.05 mg.kg

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Beneficial effect of autologous blood transfusion on infectious complications after colorectal cancer surgery

Cited by 377 publications

References 24 publications

Surgical Site Infections in Relation to the Timing of Shaving among the Gastrointestinal Emergency Patients through the Midline Incisions- A Randomized Controlled Clinical Trial

Surgical Site Infections in Relation to the Timing of Shaving among the Gastrointestinal Emergency Patients through the Midline Incisions- A Randomized Controlled Clinical Trial

What would Karl Landsteiner do? The ABO blood group and stem cell transplantation

Haemodilution tolerance in patients with mitral regurgitation

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