Abstract:At present, the aims of the investigations with microchemical
processing devices are changing from simply proving feasibility
for one chemical reaction towards more in-depth scientific
studies and industrial piloting. In this way, large data sets are
gathered, providing multifaceted information on the topic. To
enable industrial exploitation of the technology, future investigations should aim to complete the economic evaluation of
the methodology for plant engineering. Hence, commercially
oriented studies have… Show more
“…In the chemical industry numerous reactions are carried out on a large scale, which are strongly exothermic and involve two liquid phases [90]. In general, the reaction occurs in only one of the phases, but the mass transfer between the two immiscible liquids and chemical reaction are intimately linked.…”
Section: Msr For Homogeneous Catalytic Liquid Reactionsmentioning
This review addresses the catalytic reactions performed in microstructured reactors, which are more and more recognized in recent years as a novel approach for chemistry and chemical process industry. They are particularly suited for highly exothermic and fast reactions allowing temperature control and isothermal operation. A brief evaluation of the advantages for gas-phase, liquid-phase, and gas-liquid-solid reactions carried out in miniaturized devices is discussed. Alternative designs to achieve microstructured fluid patterns, besides microfabrication, are also described. #
“…In the chemical industry numerous reactions are carried out on a large scale, which are strongly exothermic and involve two liquid phases [90]. In general, the reaction occurs in only one of the phases, but the mass transfer between the two immiscible liquids and chemical reaction are intimately linked.…”
Section: Msr For Homogeneous Catalytic Liquid Reactionsmentioning
This review addresses the catalytic reactions performed in microstructured reactors, which are more and more recognized in recent years as a novel approach for chemistry and chemical process industry. They are particularly suited for highly exothermic and fast reactions allowing temperature control and isothermal operation. A brief evaluation of the advantages for gas-phase, liquid-phase, and gas-liquid-solid reactions carried out in miniaturized devices is discussed. Alternative designs to achieve microstructured fluid patterns, besides microfabrication, are also described. #
“…The last decade has seen a growing effort in the development of continuous flow chemical systems ranging from microscale [1][2][3][4][5][6][7] to milliscale. [8][9][10][11][12][13] The field has expanded in scope beyond single reactor and synthesis steps to multistep synthesis including intermediate workup and separation steps.…”
We describe the development and application of an improved, membrane-based, liquid-liquid separator. Membrane based separation relies on the exploitation of surface forces and the use of a membrane wetted by one of the phases; however, successful separation requires accurate control of pressures making the operation and implementation cumbersome. Here we present an improved separator design that integrates a pressure control element to ensure that adequate operating conditions are always maintained. Additionally, the integrated pressure control decouples the separator from downstream unit operations. A detailed examination of the controlling physical equations shows how to design the device to allow operation across a wide range of conditions. Easy to implement, multistage separations such as solvent swaps and countercurrent extractions are demonstrated. The presented design significantly simplifies applications ranging from multistep synthesis to complex multistage separations.
“…Micromixers have a broad range of applications such as for reactors [2][3][4], lab on a chip for chemical engineering [5], enhancement of chemical selectivity [6], extraction processes [7], drug discovery [8], polymer synthesis [9], and DNA amplification [10].…”
Effective and rapid mixing is essential for various chemical and biological assays. The present work describes a simple and low-cost micromixer based on magnetofluidic actuation. The device takes advantage of magnetoconvective secondary flow, a bulk flow induced by an external magnetic field, for mixing. A superparamagnetic stream of diluted ferrofluid and a non-magnetic stream are introduced to a straight microchannel. A permanent magnet placed next to the microchannel induced a non-uniform magnetic field. The magnetic field gradient and the mismatch in magnetic susceptibility between the two streams create a body force, which leads to rapid and efficient mixing. The micromixer reported here could achieve a high throughput and a high mixing efficiency of 88% in a relatively short microchannel.
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