Belotero: What we know now

Abstract

Background Belotero® Balance is a monophasic, polydensified hyaluronic acid gel filler (HAF) with a cross‐linked with 1,4‐butanediol diglycidyl ether. Belotero uses a unique, two‐step cross‐linking process yielding a highly cross‐linked, cohesive gel with characteristic soft, smooth, flowing quality. Belotero is the only monophasic, polydensified gel currently approved by the FDA. It is highly efficacious for correction of very fine lines. Belotero Balance is formulated free from lidocaine, and thus should be avoided for injections in nerve‐dense areas. Like other HAFs, the side effect profile of Belotero is minimal, and the product is temporary and reversible with hyaluronidase. Conclusion In this chapter we discuss Belotero's FDA approval, uses and indications, efficacy as compared to other HAFs, and adverse effects, as well as new products on the horizon.