Beitrag zur Histologie der Ammonshornformation

Schaffer, Karl

doi:10.1007/bf02961541

Cited by 111 publications

(37 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was Golgi himself who first (1886) demonstrated this. The fibers were seen also by Sala (1891) and Schaffer (1892). (The layer as a whole had been seen by earlier authors.)…”

mentioning

confidence: 72%

Distribution of hippocampal mossy fibers in the rat. An experimental study with silver impregnation methods

Blackstad

Brink

et al. 1970

J of Comparative Neurology

346

105

View full text Add to dashboard Cite

The paper deals with the distribution of the axons that arise in the fascia dentata and go to the hippocampus proper. Lesions were placed in the fascia dentata and degenerating mossy fibers were mapped by silver impregnation, mostly according to the method of Fink and Heimer ('67). The fascia dentata and the layer of mossy fibers in the rat form a curved and twisted structure extending from the level of the posterior aspect of the septum to the temporal tip. The horizontal serial sections used for this study were, therefore, in part interpreted by means of three-dimensional reconstructions.Mossy fibers do not enter the fimbria at any point. Degenerating fibers can be traced to the limit between regio superior (CA 1 ) and regio inferior. This dentato-hippocampal connection displays a pattern of precise localization, each level of fascia dentata projecting onto a restricted level of regio inferior. The bands of degenerated mossy fibers produced by lesions in the fascia dentata were largely oriented in the transverse direction (slightly in a temporal direction) and were somewhat wider distally than at the origin from the hilus. Very narrow bands were seen in a few animals with particularly small lesions.

show abstract

“…It was Golgi himself who first (1886) demonstrated this. The fibers were seen also by Sala (1891) and Schaffer (1892). (The layer as a whole had been seen by earlier authors.)…”

mentioning

confidence: 72%

Distribution of hippocampal mossy fibers in the rat. An experimental study with silver impregnation methods

Blackstad

Brink

et al. 1970

J of Comparative Neurology

346

105

View full text Add to dashboard Cite

show abstract

“…It is relevant to point out that the CA3-to-CA3 projections are typically called the associational connections, whereas the CA3 projections to the CA1 field are typically referred to as Schaffer collaterals, honoring the original description (Schaffer 1892). CA3 neurons also issue strong commissural projections to contralateral CA3 and CA1.…”

Section: Hippocampal Projections Originating In Ca3mentioning

confidence: 99%

Intrinsic and extrinsic wiring of CA3: Indications for connectional heterogeneity

Witter¹

2007

Learning & Memory

206

195

View full text Add to dashboard Cite

“…These fEPSPs represent the collective synaptic responses generated by activation of populations of postsynaptic CA1 neurons. Evoked fEPSPs are elicited by stimulation of Schaeffer collateral fibres (Schaeffer, 1892) using an extracellular bipolar nickel-chromium electrode (see below). These fibres provide synapses that excite the apical dendrites of CA1 pyramidal neurons.…”

Section: Hippocampal Slice Preparation and Interface Slice Chambersmentioning

confidence: 99%

Comparative plasticity of brain synapses in inbred mouse strains

Nguyen

2006

Journal of Experimental Biology

View full text Add to dashboard Cite

SUMMARY One niche of experimental biology that has experienced considerable progress is the neurobiology of learning and memory. A key contributor to such progress has been the widespread use of transgenic and `knockout' mice to elucidate the mechanisms of identifiable phenotypes of learning and memory. Inbred mouse strains are needed to generate genetically modified mice. However, genetic variations between inbred strains can confound the interpretation of cellular neurophysiological phenotypes of mutant mice. It is known that altered physiological strength of synaptic transmission (`synaptic plasticity') can modify and regulate learning and memory. Characterization of the synaptic phenotypes of inbred mouse strains is needed to identify the most appropriate strains to use for generating mutant mouse models of memory function. More importantly, comparative electrophysiological analyses of inbred mice per se can also shed light on which forms of synaptic plasticity underlie particular types of learning and memory. Many such analyses have focused on synaptic plasticity in the hippocampus because of the critical roles of this brain structure in the formation and consolidation of long-term memories. Comparative electrophysiological data obtained from several inbred mouse strains are reviewed here to highlight the following key notions: (1) synaptic plasticity is influenced by the genetic backgrounds of inbred mice; (2) the plasticity of hippocampal synapses in inbred mice is`tuned' to particular temporal patterns of activity; (3) long-term potentiation, but not long-term depression, is a cellular correlate of behavioural memory performance in some strains; (4) synaptic phenotyping of inbred mouse strains can identify cellular models of memory impairment that can be used to elucidate mechanisms that may cause specific memory deficits.

show abstract

Beitrag zur Histologie der Ammonshornformation

Cited by 111 publications

References 0 publications

Distribution of hippocampal mossy fibers in the rat. An experimental study with silver impregnation methods

Distribution of hippocampal mossy fibers in the rat. An experimental study with silver impregnation methods

Intrinsic and extrinsic wiring of CA3: Indications for connectional heterogeneity

Comparative plasticity of brain synapses in inbred mouse strains

Contact Info

Product

Resources

About