Behçet’s disease and celiac disease: a rare association or a possible link?

Abenavoli, Ludovico

doi:10.1007/s00296-009-1173-3

Cited by 3 publications

(2 citation statements)

References 4 publications

(4 reference statements)

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“…Behçet's disease (BD) is a chronic-relapsing inflammatory disease of unknown etiology. BD is characterized by frequent episodes of oral and/or genital ulcers, associated with ocular, joint, skin, and vascular involvement [118]. It is considered a form of vasculitis which primarily targets small arteries, but it can affect both arteries and veins of all sizes [119].…”

Section: Behçet's Diseasementioning

confidence: 99%

Colchicine in Managing Skin Conditions: A Systematic Review

et al. 2022

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(1) Background: Colchicine is a natural alkaloid with anti-inflammatory properties used to treat various disorders, including some skin diseases. This paper aims to incorporate all the available studies proposing colchicine as a treatment alternative in the management of cutaneous conditions. (2) Methods: In this systematic review, the available articles present in various databases (PubMed, Scopus-Embase, and Web of Science), proposing colchicine as a treatment for cutaneous pathological conditions, have been selected. Exclusion criteria included a non-English language and non-human studies. (3) Results: Ninety-six studies were included. Most of them were case reports and case series studies describing colchicine as single therapy, or in combination with other drugs. Hidradenitis suppurativa, pyoderma gangrenosum, erythema nodosum, erythema induratum, storage diseases, perforating dermatosis, bullous diseases, psoriasis, vasculitis, acne, urticaria, stomatitis, actinic keratosis, and pustular dermatosis were the main diseases discussed in literature. Although the therapeutic outcomes were variable, most of the studies reported, on average, good clinical results (4) Conclusions: Colchicine could be, as a single therapy or in combination with other drugs, a possible treatment to manage several skin diseases.

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Section: Behçet's Diseasementioning

confidence: 99%

Colchicine in Managing Skin Conditions: A Systematic Review

et al. 2022

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“…Behçet’s disease (BD) is a chronic-relapsing inflammatory pathology of unknown etiology, characterized by frequent episodes of oral and/or genital ulcers, iritis, associated with various systemic manifestations such as joint, cutaneous and vascular lesions [48]. Behcet’s disease can be traced back to an abnormal immune response due to the exposure to a particular antigen in individuals with a genetic predisposition.…”

Section: Behçet’s Diseasementioning

confidence: 99%

The Skin in Celiac Disease Patients: The Other Side of the Coin

et al. 2019

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Celiac disease (CD) is an autoimmune enteropathy that primarily affects the small intestine and is characterized by atrophy of intestinal villi. The manifestations of the disease improve following a gluten-free diet (GFD). CD is associated with various extra-intestinal diseases. Several skin manifestations are described in CD patients. The present paper reviews all CD-associated skin diseases reported in the literature and tries to analyze the pathogenic mechanisms possibly involved in these associations. Different hypotheses have been proposed to explain the possible mechanisms involved in every association between CD and cutaneous manifestations. An abnormal small intestinal permeability seems to be implicated in various dermatological manifestations. However, most of the associations between CD and cutaneous diseases is based on case reports and case series and a few controlled studies. To better assess the real involvement of the cutaneous district in CD patients, large multicentric controlled clinical trials are required.

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