Behçet disease (Behçet syndrome)

Shimizu, Tamotsu; Ehrlich, George E.; Inaba, Goro; Hayashi, Kozaburo

doi:10.1016/0049-0172(79)90004-0

Cited by 555 publications

(183 citation statements)

References 56 publications

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“…In keeping with previous studies (7,44 -47), most of our patients developed eye disease at onset or within the first few years from disease onset. Contrary to the poor prognosis for eye involvement reported by older studies (44,45,(47)(48)(49), we observed an overall favorable prognosis, in agreement with more recent studies (46,50 -52). Only 1 (11%) of 9 patients with posterior eye involvement had loss of useful vision in at least 1 eye at the end of the followup, whereas almost all patients had improvement of visual acuity once treatment was started.…”

Section: Seventeen-year Study Of Behçet's Disease In Italysupporting

confidence: 90%

Epidemiology and clinical course of Behçet's disease in the Reggio Emilia area of Northern Italy: A seventeen‐year population‐based study

Salvarani¹,

Pipitone²,

Catanoso³

et al. 2007

Arthritis & Rheumatism

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Objective. To investigate the epidemiology and clinical course of Behçet's disease (BD) over a 17-year period in a defined area of northern Italy. Methods. All patients with incident BD diagnosed over a 17-year period (from January 1, 1988 to December 31, 2004) living in the Reggio Emilia area were identified through the following sources: physicians at Reggio Emilia Hospital, medical practitioners, and community-based specialists. We identified all patients registered in a centralized index and in the Reggio Emilia district database for rare diseases. Patients were followed up from the time of diagnosis until either their death or April 1, 2005. Results. Eighteen patients (9 men and 9 women) had complete BD. Mean ؎ SD age at diagnosis was 33 ؎ 7 years. The incidence rate of BD was 0.24 per 100,000. The prevalence of BD on January 1, 2005 was 3.8 per 100,000. No patients died during the followup period. Although all patients developed oral ulceration during the disease course, 22.2% had no oral lesions at disease onset. Eye disease occurred in 55.6%. Ocular disease was more common in men and appeared at disease onset or within the first few years of disease onset (median 3 years). Only 1 patient had loss of useful vision in at least 1 eye at the end of followup. In all affected patients, visual acuity improved once treatment was started. Conclusion. This population-based study is the first to report the prevalence and incidence of BD in Italy. In Italian patients, BD is nonfatal and the prognosis of eye disease is good.

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Section: Seventeen-year Study Of Behçet's Disease In Italysupporting

confidence: 90%

Epidemiology and clinical course of Behçet's disease in the Reggio Emilia area of Northern Italy: A seventeen‐year population‐based study

Salvarani¹,

Pipitone²,

Catanoso³

et al. 2007

Arthritis & Rheumatism

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“…Seyahi and Yazici for their interest in our work regarding the interplay between BD and pregnancy and for bringing new elements to the discussion. A reduction in BD activity associated with the passage of time has been previously reported (1)(2)(3)(4)(5). Seyahi and Yazici suggest that shorter disease duration might account for the lower frequency of BD flares that we observed in our patients during pregnancy.…”

Section: Replysupporting

confidence: 80%

“…In a chart survey of pregnancy in Behçet's disease (BD), Noel and colleagues found that pregnancy favorably affected the clinical course of BD and that outcome of pregnancy was good (1). Several issues require further discussion.…”

Section: To the Editormentioning

confidence: 99%

Reply

Noël

Saadoun

2013

Arthritis & Rheumatism

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“…When present, cardiac involvement has rarely been a serious clinical problem. Isolated instances of pericarditis (9, lo), myocarditis (3,9,1 l), coronary artery aneurysm or occlusion (7,12), electrocardiographic disturbance (13), and aortic insufficiency (14) have been reported in this disease. We could find only 2 other reported cases of coronary artery occlusion and diminished left ventricular function documented by angiographic and echocardiographic methods, but in 1 case, the hepatitis B surface antigen test was positive (12,15).…”

mentioning

confidence: 98%