Behavioural and psychological symptoms of Alzheimer’s disease associated with caregiver burden and depression

Bozgeyik, Gamze; İpekçioğlu, Derya; Yazar, Menekşe Sıla; İlnem, Mehmet Cem

doi:10.1080/24750573.2018.1541646

Cited by 13 publications

(14 citation statements)

References 31 publications

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“…Behavioral psychological symptoms of dementia (BPSD) can lead to early institutionalization of patients, poor quality of life of caregivers, and increased medical expenses [4]. In a study that identified factors affecting the caregiver burden of AD patients, BPSD including hallucinations, abnormal behaviors, and insomnia was the most significant in AD patients [5].…”

Section: Relationship Of Subjective and Objective Sleep Quality With Caregiver Burden In Patients With Alzheimer's Diseasementioning

confidence: 99%

Relationship of Subjective and Objective Sleep Quality with Caregiver Burden in Patients with Alzheimer’s Disease

Lee

Kim²,

Lee³

et al. 2021

Sleep Med Res

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Background and ObjectiveaaSleep disturbance in patients with Alzheimer's disease (AD) could increase institutionalization due to caregiver burden. The objective of this study was to examine the relationship of subjective and objective sleep quality with caregiver burden in AD patients with insomnia symptoms. MethodsaaAD patients of mild to moderate degree were recruited. They were assessed with the Pittsburgh Sleep Quality Index (PSQI), Korean version of the Epworth Sleepiness Scale, and Mini-Mental Status Examination in the Korean version of Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet. Caregiver burden was evaluated with Korean version of the Neuropsychiatric Inventory Questionnaire (KNPI-Q) and Korean version of the Zarit Burden Interview (ZBI-K). Actigraphy recording (Actiwatch 2; Philips Respironics) was conducted for five days at home. Thirty-four patients (age 78.44 ± 6.14, M:F = 9:25) were analyzed. These patients were divided into two groups by the median of KNPI-Q for caregiver distress [KNPI-Q(d)] and ZBI-K scores. Sleep parameters were compared between the two groups. ResultsaaAmong seven components of PSQI, sleep latency was correlated with KNPI-Q(d) score. The patients with higher KNPI-Q(d) scores had lower sleep efficiency (SE) (p = 0.002), greater wake after sleep onset (p = 0.037), and higher fragmentation index (p = 0.040) than those with lower KNPI-Q(d) scores. Those with higher ZBI-K scores had lower SE (p = 0.026) than those with lower ZBI-K scores. Stepwise multiple regression revealed that SE predicted 16% of KNPI-Q(d) scores (p = 0.012). ConclusionsaaDifficulty in sleep initiation according to subjective reports was associated with caregiver burden in our AD patients. In objective sleep quality, a significant difference in difficulty of sleep maintenance was found between higher and lower caregiver burden groups. This suggests that sleep maintenance is essential for reducing caregiver burden.

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Section: Relationship Of Subjective and Objective Sleep Quality With Caregiver Burden In Patients With Alzheimer's Diseasementioning

confidence: 99%

Relationship of Subjective and Objective Sleep Quality with Caregiver Burden in Patients with Alzheimer’s Disease

Lee

Kim²,

Lee³

et al. 2021

Sleep Med Res

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“…5 10 Caring for people with dementia is mainly performed by informal carers, 11 including spouses, children, relatives or rarely friends who do not get paid for providing care. 12 13…”

Section: Introductionmentioning

confidence: 99%

“…Caring for people with dementia is mainly performed by informal carers, 11 including spouses, children, relatives or rarely friends who do not get paid for providing care. 12 13 Literature supports that providing BPSD related care is challenging for informal carers, 10 and they present with psychological distress, burden, depression and reduced well-being. 2 14 Conversely, the literature supports that BPSD among people with dementia is triggered or exuberated by their carers’ stress, depression, communication patterns, coping abilities and mismatch of expectations.…”

Section: Introductionmentioning

confidence: 99%

“…Caring for people with dementia is mainly performed by informal carers,11 including spouses, children, relatives or rarely friends who do not get paid for providing care 12 13. Literature supports that providing BPSD related care is challenging for informal carers,10 and they present with psychological distress, burden, depression and reduced well-being 2 14.…”

Section: Introductionmentioning

confidence: 99%

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Information needs and mHealth applications for carers of people with dementia in managing behavioural and psychological symptoms of care recipients: an integrative review protocol

2022

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IntroductionThis integrative review aims to synthesise, appraise and analyse the evidence on informal carers’ information needs, features and functions of available mHealth applications, and informal carers’ usability and engagement with mHealth applications for managing behavioural and psychological symptoms of dementia (BPSD).Methods and analysisThis integrative review will include quantitative, qualitative and mixed-methods studies and follow the ‘Preferred Reporting for Systematic Reviews and Meta-Analyses 2020’ guidelines. Peer-reviewed articles published in English from 2000 to 2021 will be included from Cochrane Library, CINHAL, Embase, MEDLINE, ProQuest and PsycINFO. Five broader concept categories will be included: ‘dementia’, ‘behavioural and psychological symptoms’, ‘informal carers’, ‘(information need’ OR ‘mHealth application)’. In title and abstract review, first, the researchers will independently screen 10% of sources for consensus, and one reviewer will screen the rest. In full-text review, two reviewers will conduct the screening process and assess the relevancy of the full-text articles using a two-point scale (high-low) and the methodological quality of included articles using the Mixed Methods Appraisal Tool. Narrative synthesis will be employed to synthesise themes. The findings may identify the need for planning interventions for carers of people with dementia concerning the management of BPSD.Ethics and disseminationEthics approval not required. This review will be published in a peer-review journal and be presented at national and international conferences.PROSPERO registration numberCRD42021238540.

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“…In the clinical setting, proper evaluation of BPSD and establishing preventive measures are urgent issues. Bozgeyik et al (2019) mentioned that the symptoms significantly affecting caregiver burden included delusions, hallucinations, excitement/aggression, depression/discomfort, anxiety, apathy, disinhibition, irritability, and abnormal motor behavior. They also found a correlation between BPSD severity and caregiver depression.…”

Section: Introductionmentioning

confidence: 99%

Verification of Trail Making Test in Elderly People with Behavioral and Psychological Symptoms of Dementia

Toda

Nagami

Katsumata³

et al. 2021

Ageing Int

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In Alzheimer's disease (AD), attention and executive dysfunction occur early in the disease. However, little is known about the relationship between these disorders and behavioral and psychological symptoms of dementia (BPSD). This study investigated the relationship between BPSD and attention and execution functions. Twenty-five patients with mild cognitive impairment (MCI) and early AD were included. Neuropsychological tests, mini-mental state examination (MMSE), Raven’s colored progressive materials (RCPM), and trail making test (TMT) were conducted for patients with dementia. The dementia behavior disturbance scale (DBD) was used for psychological and behavioral evaluations of patients with dementia. The AD group showed significantly lower MMSE, DBD, and TMT-B scores than the MCI group. Multiple regression analyses revealed a significant correlation between DBD score, MMSE, and TMT-B.Conclusion: BPSD is associated with cognitive function severity in patients with MCI and early AD, suggesting that attentional and executive functions are independent risk factors for these neural substrates.

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Behavioural and psychological symptoms of Alzheimer’s disease associated with caregiver burden and depression

Cited by 13 publications

References 31 publications

Relationship of Subjective and Objective Sleep Quality with Caregiver Burden in Patients with Alzheimer’s Disease

Relationship of Subjective and Objective Sleep Quality with Caregiver Burden in Patients with Alzheimer’s Disease

Information needs and mHealth applications for carers of people with dementia in managing behavioural and psychological symptoms of care recipients: an integrative review protocol

Verification of Trail Making Test in Elderly People with Behavioral and Psychological Symptoms of Dementia

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