Behaviors of Several Compounds as Indicators in Lithium Aluminum Hydride Titration of Functional Groups¹

Potentiometric Electrode Systems In Nonaqueous Titrimetry

“…Although this is actually a redox reaction, it is closely related to acid-base systems (124). Potential chemical indicators for this titrant have also been studied (79). Lithium aluminum amides have been substituted for lithium aluminum hydride in the titration of alcohols and phenols (78).…”

Acid-Base Titrations in Nonaqueous Solvents

“…Higuchi, Concha, and Kuramoto (59) were able to titrate very weak acids such as alcohols, acetanilide, and acetamide with lithium aluminum amide. This particular reagent does not react with the reducible functional groups that gave Higuchi and Zuck trouble when titrated with the lithium aluminum hydride (60). Spandau and Brunneck (124) propose the following equilibrium in the thionyl chloride system: L-Acids.…”

“…Burg and Campbell (21) reported the preparation of a new boron base, Na2HB(CH&, with characteristics that may make it valuable as a titrant in nonaqueous solvents. Higuchi and coworkers (59,60) found that lithium aluminum hydride and lithium aluminum amides can be used for the titration of very weak acids.…”

Volumetric Analytical Methods for Organic Compounds

“…The development of low-cross-linked resins makes possible the adaptation of ion exchange techniques in fields previously closed to it. The use of ion exchange in preliminary deionization of solutions prior to partition chromatography (52, 394, 4®4) and for preliminary group fractionations (45,61,346) is notable. Emphasis is dimin-…”