Behavioral therapy versus drug therapy in individuals with idiopathic overactive bladder: A systematic review and meta-analysis

Abstract

The aim of this study was to systematically review randomized clinical trials comparing the treatment of individuals with overactive bladder syndrome through the use of behavioral therapy versus drug therapy. A systematic electronic search of MEDLINE via PubMed, Embase, and Cochrane Library was performed, including studies indexed until August 2019. Five randomized clinical trials were included. The studies presented a high risk of bias. There was no significant difference between the evaluated treatments. Thus, behavioral therapy and drug therapy also promote the improvement of the symptoms of overactive bladder syndrome, and the behavioral therapy does not have significant adverse effects reported. Due to the high risk of bias in included studies, data should be interpreted with caution. Future studies with more comprehensive protocols may change the effect estimates of behavioral therapy on overactive bladder syndrome.

Efficacy of non‐pharmacological interventions in females with overactive bladder: A systematic review and network meta‐analysis

“…Due to its effectiveness in improving bladder function, minimal risk and easier implementation, a broad range of non‐pharmacological interventions are receiving extensive attention. Such interventions include, but are not restricted to, behavioural therapy (BT; Elnaggar et al, 2020; La Rosa et al, 2020; Wyman et al, 2009), acupuncture (Mak et al, 2019) and electric stimulation (ES; Fernandez et al, 2017).…”

Efficacy of non‐pharmacological interventions in patients with overactive bladder: A protocol for systematic review and network meta‐analysis

“…Due to the concern about the side effects of medicine and complications of the surgery (Kim et al, 2017;Liedl et al, 2017), multiple non-pharmacological interventions are receiving extensive attention as a vital part of treating OAB. Several meta-analyses have been conducted to compare the effectiveness and safety of nonpharmacological strategies on the symptoms of OAB, including bladder training (Cao et al, 2016), acupuncture (Mak et al, 2019), electric stimulation (Booth et al, 2018Fernandez et al, 2017;Wang et al, 2020) and behavioural therapy (La Rosa et al, 2020). Up to our knowledge, there is only one study that showed the combination is the most effective treatment (Firinci et al, 2020).…”