Behavioral Tests for Evaluation of Information Processing and Cognitive Deficits in Rodent Animal Models of Neuropsychiatric Disorders

Stuchlı́k, Aleš; Petrásek, Tomáš; Hatalova, Hana; Rambousek, Lukáš; Nekovarova, Tereza; Valeš, Karel

doi:10.5772/37844

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Bz In Behavioral Studies -Impact On Learning and Memory1

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Cited by 4 publications

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“…2). The Morris Water Maze is a common and widely used behavioral test for spatial learning and memory, requiring search for the hidden platform submerged in the circular pool [12,19]. Agent BZ at the dose of 2.0 mg.kg -1 induces disorientation in performing rats, characterized by a prolonged path and escape latency with insignificant side effects as locomotoric and attentional disruption [6,20].…”

Section: Bz In Behavioral Studies -Impact On Learning and Memorymentioning

confidence: 99%

Military Incapacitating Agent Bz (3-Quinuclidinyl Benzilate) - Past, Present and Future

Mišík¹

2013

Mil. Med. Sci. Lett.

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The military incapacitating agent BZ (3-quinuclidinyl benzilate) is an anticholinergic compound that acts at both, the peripheral and central nervous system. Effects of the agent were discovered during the Cold War and BZ became one of the most potent anticholinergic psychomimetics, characterized by low effective doses causing long-term incapacitation. History, characteristics and potential use of BZ in behavioral research are discussed throughout this review.

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