Behavioral Interventions in Attention-Deficit/Hyperactivity Disorder: A Meta-Analysis of Randomized Controlled Trials Across Multiple Outcome Domains

Daley, David; Oord, Saskia Van der; Ferrín, Maite; Danckaerts, Marina; Döepfner, Manfred; Cortese, Samuele; Sonuga‐Barke, Edmund

doi:10.1016/j.jaac.2014.05.013

Cited by 321 publications

(335 citation statements)

References 143 publications

(27 reference statements)

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“…With regard to the former, preschool behavioural parenting approaches have been shown to reduce parent‐rated hyperactivity scores by significant amounts (Daley et al., 2014). While a formal cost‐benefit analysis based on the long‐term costs of preschool‐hyperactivity has not been completed, the scale of the costs identified in this study suggest that the use of parent training for those screened positive for both hyperactivity and conduct problems could be cost effective.…”

Section: Discussionmentioning

confidence: 99%

“…Although it has its developmental roots in the preschool years (Sonuga‐Barke & Halperin, 2010), ADHD is normally first diagnosed and treated in middle to late childhood. A combination of medication (Banaschewski et al., 2006) and psycho‐social treatments (Daley et al., 2014) is recommended. Medications are efficacious and cost effective (NICE, 2009).…”

Section: Introductionmentioning

confidence: 99%

“…Recent meta‐analyses, focusing on studies with blinded outcomes, have highlighted the potentially limited value of psychological and dietary approaches (Sonuga‐Barke et al., 2013). Behavioural parent training was, however, of value in relation to co‐occurring conduct problems (Daley et al., 2014) and cognitive training helped ADHD‐related neuropsychological deficits (Cortese et al., 2015). Dietary exclusions and supplements may have a role in some cases (Stevenson et al., 2014).…”

Section: Introductionmentioning

confidence: 99%

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Preschool hyperactivity is associated with long‐term economic burden: evidence from a longitudinal health economic analysis of costs incurred across childhood, adolescence and young adulthood

Chorozoglou

Smith

Koerting

et al. 2015

Child Psychology Psychiatry

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BackgroundPreschool hyperactivity is an early risk factor for adult mental health problems and criminality. Little is known about; (a) the patterns of long‐term service costs associated with this behavioural marker in the general population and (b) the specific factors predicting hyperactivity‐related costs. We undertook a prospective study investigating associations between preschool hyperactivity and average individual annual service costs up to late adolescent and young adulthood.MethodsOne‐hundred and seventy individuals rated as hyperactive by their parents and 88 nonhyperactive controls were identified from a community sample of 4,215 three years olds. Baseline information about behaviour/emotional problems and background characteristics were collected. At follow‐up (when individuals were aged between 14 and 25 years) information was obtained on service use, and associated costs since the age of three. Based on this information we calculated the average cost per annum incurred by each individual.ResultsCompared to controls, preschoolers with hyperactivity had 17.6 times higher average costs per annum across domains (apart from nonmental health costs). These were £562 for each hyperactive individual compared with £30 for controls. Average annual costs decreased as a function of age, with higher costs incurred at younger ages. The effects of hyperactivity remained significant when other baseline factors were added to the model. Effects were fully mediated by later psychiatric morbidity. When the hyperactive group were examined separately, costs were consistently predicted by male gender and, for some cost codes, by conduct problems.ConclusionsPreventative approaches targeting early hyperactivity may be of value. Services should be targeted towards high‐risk individuals with careful consideration given to the cost‐to‐benefit trade‐off of early intervention strategies.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Preschool hyperactivity is associated with long‐term economic burden: evidence from a longitudinal health economic analysis of costs incurred across childhood, adolescence and young adulthood

Chorozoglou

Smith

Koerting

et al. 2015

Child Psychology Psychiatry

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“…Non-pharmacological interventions -both dietary and psychological -have been also extensively investigated [4][5][6][7] . Among nonpharmacological approaches, neurofeedback has been considered a promising ADHD treatment strategy since the early 1970s [8][9][10] .…”

Section: Introductionmentioning

confidence: 99%

“…Applying the same meta-analyses protocol used in recent EAGG reviews of behavioural interventions 5 and cognitive training 4 , we here extend the focus of meta-analytic evidence relating to neurofeedback for ADHD in a number of ways. First, we included, among the outcomes, not only specific ADHD behavioral dimensions (i.e., inattention and impulsivity/hyperactivity) but also ADHD-related neuropsychological deficits such as inhibitory dysfunction.…”

Section: Introductionmentioning

confidence: 99%

The European ADHD Guidelines Group replies:

Cortese

Brandeis

Holtmann

et al. 2016

Journal of the American Academy of Child & Adolescent Psych

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A Brief Home-Based Parenting Intervention to Reduce Behavior Problems in Young Children

et al. 2021

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Behavior problems are one of the most common mental health disorders in childhood and can undermine children's health, education, and employment outcomes into adulthood. There are few effective interventions for early childhood. OBJECTIVE To test the clinical effectiveness of a brief parenting intervention, the Video-feedback Intervention to promote Positive Parenting and Sensitive Discipline (VIPP-SD), in reducing behavior problems in children aged 12 to 36 months. DESIGN, SETTING, AND PARTICIPANTS The Healthy Start, Happy Start study was a 2-group, parallel-group, researcher-blind, multisite randomized clinical trial conducted via health visiting services in 6 National Health Service trusts in England. Baseline and 5-month follow-up data were collected between July 30, 2015, and April 27, 2018. Of 818 eligible families, 227 declined to participate, and 300 were randomized into the trial. Target participants were caregivers of children who scored in the top 20% for behavior problems on the Strengths and Difficulties Questionnaire. Participants were randomly allocated on a 1:1 basis to receive either VIPP-SD (n = 151) or usual care (n = 149), stratified by site and number of participating caregivers. Analysis was performed on an intention-to-treat basis. Statistical analysis was performed from September 5, 2019, to January 17, 2020. INTERVENTIONS All families continued to access usual care. Families allocated to VIPP-SD were offered 6 home-based video-feedback sessions of 1 to 2 hours' duration every 2 weeks. MAIN OUTCOMES AND MEASURES The primary outcome was the score on an early childhood version of the Preschool Parental Account of Children's Symptoms, a semistructured interview of behavior symptoms, at 5 months after randomization. Secondary outcomes included caregiver-reported behavior problems on the Child Behavior Checklist and the Strengths and Difficulties Questionnaire. RESULTS Among 300 participating children (163 boys [54%]; mean [SD] age, 23.0 [6.7] months), primary outcome data were available for 140 of 151 VIPP-SD participants (93%) and 146 of 149 usual care participants (98%). There was a mean difference in the total Preschool Parental Account of Children's Symptoms score of 2.03 (95% CI, 0.06-4.01; P = .04; Cohen d = 0.20 [95% CI, 0.01-0.40]) between trial groups, with fewer behavior problems in the VIPP-SD group, particularly conduct symptoms (mean difference, 1.61 [95% CI, 0.44-2.78]; P = .007; d = 0.30 [95% CI, 0.08-0.51]). Other child behavior outcomes showed similar evidence favoring VIPP-SD. No treatment or trial-related adverse events were reported. CONCLUSIONS AND RELEVANCE This study found that VIPP-SD was effective in reducing symptoms of early behavior problems in young children when delivered in a routine health service context.

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Behavioral Interventions in Attention-Deficit/Hyperactivity Disorder: A Meta-Analysis of Randomized Controlled Trials Across Multiple Outcome Domains

Cited by 321 publications

References 143 publications

Preschool hyperactivity is associated with long‐term economic burden: evidence from a longitudinal health economic analysis of costs incurred across childhood, adolescence and young adulthood

Preschool hyperactivity is associated with long‐term economic burden: evidence from a longitudinal health economic analysis of costs incurred across childhood, adolescence and young adulthood

The European ADHD Guidelines Group replies:

A Brief Home-Based Parenting Intervention to Reduce Behavior Problems in Young Children

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