Behavioral and neural correlates of visual emotion discrimination and empathy in mild cognitive impairment

Pernigo, Simone; Gambina, Giuseppe; Valbusa, Valeria; Condoleo, M. T.; Broggio, Elisabetta; Beltramello, Alberto; Moretto, Giuseppe; Moro, Valentina

doi:10.1016/j.bbr.2015.07.047

Cited by 11 publications

(20 citation statements)

References 135 publications

(165 reference statements)

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“…Recent research has found that deficits in visual recognition of facial emotions in aMCI individuals may arise already in the earliest stage of memorization, during the encoding of facial emotions [ 24 ]. Electrophysiological evidence also points to impairments in face recognition processes and emotional memory in the early coding stages in aMCI [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

“…Electrophysiological evidence also points to impairments in face recognition processes and emotional memory in the early coding stages in aMCI [ 25 ]. Voxel-based morphometry revealed some association between these deficits in aMCI and atrophy in frontal and occipito-temporal regions [ 24 ]. Since the disorder was not related to the extent (single or multiple domain) of the cognitive impairment but rather to the involvement of frontal brain networks, the authors concluded that in prodromal stages of dementia, frontal symptoms may represent a significant signal of emotional recognition disorder [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

“…Voxel-based morphometry revealed some association between these deficits in aMCI and atrophy in frontal and occipito-temporal regions [ 24 ]. Since the disorder was not related to the extent (single or multiple domain) of the cognitive impairment but rather to the involvement of frontal brain networks, the authors concluded that in prodromal stages of dementia, frontal symptoms may represent a significant signal of emotional recognition disorder [ 24 ]. aMCI subjects with frontal symptoms and atrophy may present early disorders in the visual perception of negative facial expressions, irrespective of their general cognitive decline.…”

Section: Discussionmentioning

confidence: 99%

“…aMCI subjects with frontal symptoms and atrophy may present early disorders in the visual perception of negative facial expressions, irrespective of their general cognitive decline. Moreover, cognitive aspects of empathy may be reduced in aMCI and the general deficit in visual form discrimination is associated with temporo-mesial and occipital atrophy [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

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Memory deficits for facial identity in patients with amnestic mild cognitive impairment (MCI)

Savaskan¹,

Summermatter²,

Schroeder³

et al. 2018

PLoS ONE

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Faces are among the most relevant social stimuli revealing an encounter’s identity and actual emotional state. Deficits in facial recognition may be an early sign of cognitive decline leading to social deficits. The main objective of the present study is to investigate if individuals with amnestic mild cognitive impairment show recognition deficits in facial identity. Thirty-seven individuals with amnestic mild cognitive impairment, multiple-domain (15 female; age: 75±8 yrs.) and forty-one healthy volunteers (24 female; age 71±6 yrs.) participated. All participants completed a human portrait memory test presenting unfamiliar faces with happy and angry emotional expressions. Five and thirty minutes later, old and new neutral faces were presented, and discrimination sensitivity (d’) and response bias (C) were assessed as signal detection parameters of cued facial identity recognition. Memory performance was lower in amnestic mild cognitive impairment as compared to control subjects, mainly because of an altered response bias towards an increased false alarm rate (favoring false OLD ascription of NEW items). In both groups, memory performance declined between the early and later testing session, and was always better for acquired happy than angry faces. Facial identity memory is impaired in patients with amnestic mild cognitive impairment. Liberalization of the response bias may reflect a socially motivated compensatory mechanism maintaining an almost identical recognition hit rate of OLD faces in individuals with amnestic mild cognitive impairment.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Memory deficits for facial identity in patients with amnestic mild cognitive impairment (MCI)

Savaskan¹,

Summermatter²,

Schroeder³

et al. 2018

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Some studies suggest that cognitive empathy progressively diminishes (Henry, Phillips, Ruffman, & Bailey, 2013;Moran, 2013;Sun, Luo, Zhang, Li, & Li, 2018) while emotional empathy seems to remain stable or even improve over time (Sun, et al, 2018;Sze, Gyurak, Goodkind, & Levenson, 2012;Ze, Thoma, & Suchan, 2014). Nevertheless, the scientific literature on empathy and normal aging is mostly based on self-reported questionnaires, which cannot easily be exempt from unwanted social desirability bias (Pernigo et al, 2015;van de Mortel, 2008).…”

Section: Introductionmentioning

confidence: 99%

Effects of age and sex on neurophysiological substrates of empathy: a cross-sectional EEG study

Guay¹,

Héroux²,

Joubert³

et al. 2018

Preprint

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Although empathy is an indispensable competence to social adaptation throughout the lifespan, it has been mostly studied with subjective, questionnaire-based measures in the context of healthy aging. Electroencephalography (EEG) provides an objective measure to investigate underlying neurophysiological processes related to empathy through mu rhythm. The current study used empathy-related mu rhythm during the observation of emotional facial expressions (EFE) in addition to the Empathy Quotient questionnaire in order to explore age-related changes of empathy across sexes. A total of 65 participants, including 33 young adults and 32 seniors, took part in this study. They were instructed to observe as well as to try experiencing emotional facial expressions (joy, fear, neutral) depicted on short video clips during which continuous EEG was recorded. They also completed the Empathy Quotient (EQ) questionnaire. Young adults reacted more strongly to emotional EFEs. Seniors perceived themselves as less empathic and exhibited an equivalent neurophysiological response to emotional and neutral stimuli. A significant sex effect in favour of females was found on mu rhythm modulation. Mu rhythm appears to be an age and sex sensitive neurophysiological marker linked to empathy and could therefore serve as an objective measure of empathy.

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Comprehension of written texts for the assessment of clinical competence and decision making in people with mild to moderate Alzheimer disease

et al. 2020

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Behavioral and neural correlates of visual emotion discrimination and empathy in mild cognitive impairment

Cited by 11 publications

References 135 publications

Memory deficits for facial identity in patients with amnestic mild cognitive impairment (MCI)

Memory deficits for facial identity in patients with amnestic mild cognitive impairment (MCI)

Effects of age and sex on neurophysiological substrates of empathy: a cross-sectional EEG study

Comprehension of written texts for the assessment of clinical competence and decision making in people with mild to moderate Alzheimer disease

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