Behavior-Related Erectile Dysfunction: A Systematic Review and Meta-Analysis

Sivaratnam, Lavanyah; Selimin, Diana Safraa; Ghani, Siti Rasidah Abd; Nawi, Haniff Mohd; Nawi, Azmawati Mohammed

doi:10.1016/j.jsxm.2020.09.009

“…This includes mental health, smoking, alcohol consumption, and BMI. 15 , 16 , 17 Unfortunately, our sample size is too small to correlate these variables with the primary results we have for the metoidioplasty population facing sexual challenges and their willingness to pursue remedial measures.…”

Section: Discussionmentioning

confidence: 99%

The Sexual Goals of Metoidioplasty Patients and Their Attitudes Toward Using PDE5 Inhibitors and Intracavernosal Injections as Erectile Aids

Khorrami

¹

,

Kumar

²

,

Bertin

³

et al. 2022

Sexual Medicine

3

0

View full text Add to dashboard Cite

Background Following metoidioplasty, transmen (TM) experience sexual function challenges including erectile dysfunction, which is typically treated in cisgender men with phosphodiesterase-5 inhibitors (PDE5i) and intracavernosal injections (ICI). Aim We aim to evaluate sexual function post-metoidioplasty and explore attitudes toward using PDE5i and ICI as potential erectile aids Methods All patients who had metoidioplasty completed at the Gender Surgery Program in Vancouver, British Columbia were contacted. Participants completed an electronically accessible self-constructed questionnaire consisting of 39 items on erectile function, orgasm, and penetrative intercourse which also captured Erection Hardness Scores (EHS). Data were analyzed via t-test and 1-way ANOVA. Outcomes Our outcomes were the importance of erectile function, ability to orgasm, penetrative intercourse, and attitudes towards using PDE5i and ICI post-metoidioplasty. Results Fifteen out of 22 patients completed the survey (median age 32 years). Most had metoidioplasty within the past 2 years. The participants ranked the ability to orgasm and to achieve or maintain erections significantly higher than penetrative intercourse (P <.001, P =.005 respectively). Most participants reported facing challenges with penetrative intercourse (87%) and erectile function (80%). In contrast, a smaller proportion reported challenges with orgasm (33%). With regards to EHS, 83% of participants described their erections as either “larger but not hard,” or “hard but not hard enough for penetration.” A total of 47% of the participants had previously tried PDE5i, but none had used ICI. Although 87% were willing to use PDE5i, only 40% were willing to try ICI to improve their erections. Patients reported lack of knowledge and understanding among primary care physicians as barriers to accessing treatment for sexual dysfunction. Clinical Translation The results of this study can facilitate decision making for TM undergoing genital gender-affirmation surgery and provide potential options for improving erectile function post surgery. Strengths & Limitations This study represents the first assessment of sexual function and use of erectile aids in post-metoidioplasty patients. The results of this study are limited by the small sample size and enrolment from a single surgical center. Conclusion Metoidioplasty patients surveyed fail to achieve a fully rigid erection without treatment, typically retain the ability to orgasm, and are generally willing to try PDE5i.

show abstract

“… 28 , 29 Coital frequency, one component of sexuality, has been shown to be associated with a number of benefits for physical health. 30 , 31 , 32 , 33 , 34 , 35 It has been proven that men with an active sex life are healthier and happier 36 , 37 and have better cognitive ability 38 and life expectancy. 39 The apparent protective role of sexual activity for health may be attributable, at least in part, to the release of endorphins during sexual activity.…”

Section: Discussionmentioning

confidence: 99%

What Influences Coital Frequency Among Chinese Men?: A Cross-Sectional Study

Xiang

¹

,

Peng

²

,

Yang

³

et al. 2021

View full text Add to dashboard Cite

Introduction There are many Western reports on factors influencing coital frequency among men. However, no articles could be found about the factors influencing sexual activity among Chinese men. Aim The aim of this study was to identify the factors that influence the coital frequency of Chinese men. Main Outcome Measures The main outcome measures included self-reported monthly coital frequency, age, occupation, education level, andrology-related scales and dietary habits. Methods Data for 1,407 men aged 18–79 years were collected in the Health Management Center of the Third Xiangya Hospital of Central South University from January 2019 to May 2019. The respondents completed the questionnaires independently or with the help of an interviewer (who read or explained the questionnaires to them) to analyse the factors that influence coital frequency. Results In the previous 6 months, the sample had a mean monthly coital frequency (±SD) of 4.34 ± 3.18. Univariate logistic regression results indicated that the number of children ( P = 0.004), IIEF-5 scores ( P <0.001), EHSs ( P <0.001) and frequency of milk consumption ( P = 0.001) were associated with more frequent sexual activity. These statistical associations did not change after further adjustment for age, occupation, and reproductive history. We observed that the frequency of sexual activity showed an increasing trend with a greater number of children, higher IIEF-5 scores, higher EHSs and greater frequency of milk consumption (test for trend, P <0.05). Both univariate and multivariate analysis results indicated that the frequency of sexual activity decreased with increasing age (test for trend, P<0.001). Conclusion The coital frequency of Chinese men is associated with erectile function, anthropometric parameters, age, occupation, and dietary habits. Xiang Y, Peng J, Yang J, et al. What Influences Coital Frequency Among Chinese Men?: A Cross-Sectional Study. Sex Med 2021;9:100363.

show abstract

“…A sedentary lifestyle doubles the risk of having ED, whereas physical activity (PA) has been identified as the strongest lifestyle factor associated with improved erectile function [ 52 ]. Evidence suggests that the leading mechanisms through which PA improves ED is weight loss and increased endothelial nitric oxide production [ 52 ].…”

Section: Therapymentioning

confidence: 99%

“…A sedentary lifestyle doubles the risk of having ED, whereas physical activity (PA) has been identified as the strongest lifestyle factor associated with improved erectile function [ 52 ]. Evidence suggests that the leading mechanisms through which PA improves ED is weight loss and increased endothelial nitric oxide production [ 52 ]. As shown in a RCT [ 49 ] the implementation of PA in men with ED ameliorates endothelial dysfunction and vascular inflammation, thus resulting in a 4.0-point improvement of the IIEF-5 score.…”

Section: Therapymentioning

confidence: 99%

The Italian Society of Andrology and Sexual Medicine (SIAMS), along with ten other Italian Scientific Societies, guidelines on the diagnosis and management of erectile dysfunction

Corona

¹

,

Cucinotta

²

,

Lorenzo

³

et al. 2023

J Endocrinol Invest

View full text Add to dashboard Cite

Purpose Erectile dysfunction (ED) is one of the most prevalent male sexual dysfunctions. ED has been in the past mistakenly considered a purely psycho-sexological symptom by patients and doctors. However, an ever-growing body of evidence supporting the role of several organic factors in the pathophysiological mechanisms underlying ED has been recognized. Methods The Italian Society of Andrology and Sexual Medicine (SIAMS) commissioned an expert task force involving several other National Societies to provide an updated guideline on the diagnosis and management of ED. Derived recommendations were based on the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system. Results Several evidence-based statements were released providing the necessary up-to-date guidance in the context of ED with organic and psychosexual comorbidities. Many of them were related to incorrect lifestyle habits suggesting how to associate pharmacotherapies and counseling, in a couple-centered approach. Having the oral therapy with phosphodiesterase type 5 inhibitors as the gold standard along with several other medical and surgical therapies, new therapeutic or controversial options were also discussed. Conclusions These are the first guidelines based on a multidisciplinary approach that involves the most important Societies related to the field of sexual medicine. This fruitful discussion allowed for a general agreement on several recommendations and suggestions to be reached, which can support all stakeholders in improving couple sexual satisfaction and overall general health. Supplementary Information The online version contains supplementary material available at 10.1007/s40618-023-02015-5.

show abstract

Behavior-Related Erectile Dysfunction: A Systematic Review and Meta-Analysis

Cited by 20 publications

References 50 publications

The Sexual Goals of Metoidioplasty Patients and Their Attitudes Toward Using PDE5 Inhibitors and Intracavernosal Injections as Erectile Aids

The Sexual Goals of Metoidioplasty Patients and Their Attitudes Toward Using PDE5 Inhibitors and Intracavernosal Injections as Erectile Aids

What Influences Coital Frequency Among Chinese Men?: A Cross-Sectional Study

The Italian Society of Andrology and Sexual Medicine (SIAMS), along with ten other Italian Scientific Societies, guidelines on the diagnosis and management of erectile dysfunction

Contact Info

Product

Resources

About