Behavior of rat stomach kallikrein-like substance in experimental gastric ulceration occurrence

Suzuki, Yohichi; Yokozawa, Yoshitsugu; Yoshida, Makoto; Otsuka, Sachio; Shirai, Toshikazu; Yoshida, Ryoko; Igarashi, Michiko; Asada, Toshio; Takagi, Yoshio; Akima, Michio; Fujii, Susumu

doi:10.2491/jjsth1970.11.544

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1983

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Bo'ih direct proteolytic, as well as plasminogen activating effects have been identified in the gastric mucosa [9, lo], and there are indications that certain diseases of the stomach are associated with an abnormally increased [3,10,11] or decreased [12] fibrinolytic activity.…”

Section: Discussionmentioning

confidence: 99%

Fibrinolytic activity of the gastric mucosa in Ménétrièr's disease

Wijngaards¹,

Jespersen

1983

Eur J Clin Investigation

View full text Add to dashboard Cite

Biopsies of the gastric mucosa were collected from two patients with Ménétrièr's disease before, during, and after treatment with cimetidine and studied for fibrinolytic activity. The fibrinolytic activity in the homogenates or in the potassium thiocyanate soluble fractions increased markedly during the treatment. Immunological characterization of the activity indicated that its major component was an endothelium-derived type of plasminogen activator, and that the increase in activity was caused solely by an increase in the concentration of this component. This suggests an increase in the vascularity of the mucosal layers during treatment thus reflecting a repair process.

show abstract

Section: Discussionmentioning

confidence: 99%