Behavior of helical coil with water cooling channel and temperature dependent conductivity of copper winding used for MFH purpose

Gas, Pacific

doi:10.1088/1755-1315/214/1/012124

Cited by 11 publications

(7 citation statements)

References 16 publications

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“…The two laws were obtained by fitting the curve of the temperature measured in the air region closer to the quartz holder wall. In this way, we took into account possible heating effects produced by the copper coil via Joule losses [ 69 ] and by the sample itself in the external air region. It is worth noting that at the end of the heating phase, an increase in T ext up to 9 °C was found.…”

Section: Resultsmentioning

confidence: 99%

Experimental and Modelling Analysis of the Hyperthermia Properties of Iron Oxide Nanocubes

et al. 2021

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The ability of magnetic nanoparticles (MNPs) to transform electromagnetic energy into heat is widely exploited in well-known thermal cancer therapies, such as magnetic hyperthermia, which proves useful in enhancing the radio- and chemo-sensitivity of human tumor cells. Since the heat release is ruled by the complex magnetic behavior of MNPs, a careful investigation is needed to understand the role of their intrinsic (composition, size and shape) and collective (aggregation state) properties. Here, the influence of geometrical parameters and aggregation on the specific loss power (SLP) is analyzed through in-depth structural, morphological, magnetic and thermometric characterizations supported by micromagnetic and heat transfer simulations. To this aim, different samples of cubic Fe3O4 NPs with an average size between 15 nm and 160 nm are prepared via hydrothermal route. For the analyzed samples, the magnetic behavior and heating properties result to be basically determined by the magnetic single- or multi-domain configuration and by the competition between magnetocrystalline and shape anisotropies. This is clarified by micromagnetic simulations, which enable us to also elucidate the role of magnetostatic interactions associated with locally strong aggregation.

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Section: Resultsmentioning

confidence: 99%

Experimental and Modelling Analysis of the Hyperthermia Properties of Iron Oxide Nanocubes

et al. 2021

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“…Therefore, it is suitable for applications that require surface heating and could have some degree of penetration depending on the intensity of the magnetic field. Other geometries, such as a helical configuration, require the target object to be inserted inside the coil [48][49][50]. A 'pancake' planar configuration met this project's goal of applying AMFs to other surfaces.…”

Section: Magnetic Field Generator Designmentioning

confidence: 99%

Development of handheld induction heaters for magnetic fluid hyperthermia applications and in-vitro evaluation on ovarian and prostate cancer cell lines

Castro-Torres

Mendéz²,

Torres‐Lugo³

et al. 2023

Biomed. Phys. Eng. Express

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Abstract— Objective: Magnetic fluid hyperthermia (MFH) is a still experimental technique found to have a potential application in the treatment of cancer. The method aims to reach around 41–47°C in the tumor site by exciting magnetic nanoparticles with an externally applied alternating magnetic field (AMF), where cell death is expected to occur. Applying AMFs with high spatial resolution is still a challenge. The AMFs from current and prospective MFH applicators cover relatively large areas; being not suitable for patients having metallic implants near the treatment area. Thus, there will be a clinical need for smaller magnetic field applicators. To this end, a laparoscopic induction heater (LIH) and a transrectal induction heater (TRIH) were developed. Methods: Miniature “pancake” coils were wound and inserted into 3D printed enclosures. Ovarian (SKOV-3, A2780) and prostate (PC-3, LNCaP) cancer cell lines were used to evaluate the instruments’ capabilities in killing cancer cells in vitro, using Synomag®-D nanoparticles as the heat mediators. NIH3T3 normal cell lines were also used with both devices to observe if these cells tolerated the conditions applied. Results: Magnetic field intensities reached by the LIH and TRIH were 42.6 kA/m at 326 kHz and 26.3 kA/m at 303 kHz, respectively. Temperatures reached in the samples were 41°C by the LIH and 43°C by the TRIH. Both instruments successfully accomplished killing cancer cells, with minimal effects on normal cells. Conclusion: This work presents the first line of handheld medical induction heaters and have the potential to be a complement to existing cancer therapies. Significance: These instruments could enable the development of MFH modalities that will facilitate the clinical translation of this thermal treatment.

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“…The equation shows that the shear rate depends on the distance from the axis. Substituting equations (2) and (3) in to equation 1, we obtain the dependence…”

Section: Torque Friction Modelmentioning

confidence: 99%

“…In order to maintain stability, particles are coated with a surface active substance (surfactant) to prevent agglomeration. Thanks to their properties, ferrofluids are used in waste processing, material recycling, sensors and speakers, 2 in biomedical applications, 3 or as lubricants. 4…”

Section: Introductionmentioning

confidence: 99%

Theoretical analysis and experimental studies on torque friction in magnetic fluid seals

Szczęch

2019

Proceedings of the Institution of Mechanical Engineers, Part J:

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Magnetic fluid seals are among the most common applications of ferrofluids. In such seals, the torque friction results only from the internal friction in the fluid and there is no direct contact between seal elements. Despite this, the heat generated during operation can be significant due to the low volume of the ferrofluid in the seal and high rotational speeds. The difficulty in calculating the torque friction is because the ferrofluid is a non-Newtonian fluid and changes its viscosity under the influence of a magnetic field. In order to measure torque friction in magnetic fluid seals, a special test stand was built. Tests were performed at different rotation speeds, different temperatures, and two seal stage geometries (rectangle and trapezoid). Numerical simulations were performed to determine the magnetic field distribution in the seal. Dynamic viscosity under the influence of the magnetic field was measured on a rotary rheometer. Mathematical models were compared with laboratory results. The results obtained from the calculations in some cases gave overstated values almost twice in value. An additional correction in the case of ferrofluid viscosity is proposed.

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Behavior of helical coil with water cooling channel and temperature dependent conductivity of copper winding used for MFH purpose

Cited by 11 publications

References 16 publications

Experimental and Modelling Analysis of the Hyperthermia Properties of Iron Oxide Nanocubes

Experimental and Modelling Analysis of the Hyperthermia Properties of Iron Oxide Nanocubes

Development of handheld induction heaters for magnetic fluid hyperthermia applications and in-vitro evaluation on ovarian and prostate cancer cell lines

Theoretical analysis and experimental studies on torque friction in magnetic fluid seals

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