Behandlungserfolg auch bei höherer Schmerzchronifizierung?

Hüppe, Michael; Maier, Christoph; Gockel, H.; Zenz, M.; Frettlöh, Jule

doi:10.1007/s00482-010-0999-7

Cited by 17 publications

(4 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Treatment success based on stages of chronification has been retrospectively investigated by Huppe et al ( 2011 ) in a large cohort of patients ( n = 1461) using the Mainz pain staging system (MPSS). Main diagnosis of pain were headache ( n = 164), neuropathic pain ( n = 338), back pain ( n = 689), and muscle, joint and bone pain ( n = 270).…”

Section: Discussionmentioning

confidence: 99%

Treatment of peripheral neuropathic pain by topical capsaicin: Impact of pre‐existing pain in the QUEPP‐study

Maihöfner

Heskamp

2013

European Journal of Pain

View full text Add to dashboard Cite

BackgroundThis study evaluates the impact of the duration of pre-existing peripheral neuropathic pain on the therapeutic response to the capsaicin 8% cutaneous patch.MethodsThe non-interventional QUEPP (QUTENZA – safety and effectiveness in peripheral neuropathic pain) study evaluated the effectiveness of Qutenza™ in 1044 non-diabetic patients with peripheral neuropathic pain, who received a single application. Follow-up visits were scheduled at weeks 1–2, 4, 8 and 12. A pre-defined co-analysis of changes in average pain intensity was performed based on the duration of pre-existing pain.ResultsIn patients with pre-existing pain for <6 months, the mean relative change of the numeric pain rating scale score on days 7–14 to week 12 versus baseline was −36.6% [4.6 standard error of the mean (SEM); n = 105], −25.1% (1.9 SEM; n = 311) in patients with pain duration of 6 months to 2 years, −22.3% (1.6 SEM; n = 391) in patients with pain for >2–10 years, and −19.2% (2.6 SEM; n = 99) in patients with pain for >10 years. Thirty percent and 50% responder rates were 61.7% and 39.3% in patients with pre-existing pain for <6 months, 42.3% and 23.3% in patients with pain for 6 months to 2 years, 40.9% and 21.6% in patients with pain for >2–10 years, and 32.3% and 14.1% in patients with pain for >10 years.ConclusionsThe highest treatment response to the capsaicin 8% cutaneous patch was observed in patients with a history of pre-existing peripheral neuropathic pain of less than 6 months, suggesting that early initiation of topical treatment might be indicated.

show abstract

Section: Discussionmentioning

confidence: 99%

Treatment of peripheral neuropathic pain by topical capsaicin: Impact of pre‐existing pain in the QUEPP‐study

Maihöfner

Heskamp

2013

European Journal of Pain

View full text Add to dashboard Cite

show abstract

“…Further, it is yet unclear which role pain chronification might play in the associations between incongruence, pain and distress. Pain chronification was found to be linked to treatment resistance (Borsook, Youssef, Simons, Elman, & Eccleston, 2018), but improvements of outcomes in pain intensity and psychological disability seem to occur in all stages of pain chronification (Hüppe, Maier, Gockel, Zenz, & Frettlöh, 2011). In our analysis, we controlled for illness duration, i.e., pain chronification.…”

Section: Clinical Implications Limitations and Future Researchmentioning

confidence: 99%

Motive Satisfaction in Chronic Pain Patients: Does It Improve in Multidisciplinary Inpatient Treatment and, if so, Does It Matter?

Vincent

Stewart

Egloff

et al. 2020

J Clin Psychol Med Settings

View full text Add to dashboard Cite

According to consistency theory, insufficient motive satisfaction (motivational incongruence) is associated with psychological distress and mental disorders. High levels of distress and comorbid psychological disorders are common in patients with chronic pain. The aim of the present study was to investigate the role of motivational incongruence in chronic pain patients and the association of incongruence change with symptom improvement. Inpatients with chronic pain in multimodal interdisciplinary treatment (n = 177) completed questionnaires measuring motivational incongruence, psychological distress, pain intensity and pain interference at the beginning and end of a multimodal interdisciplinary inpatient treatment program at a tertiary psychosomatic university clinic. Results demonstrated that pain and motivational incongruence were significantly reduced at post-treatment, and reductions in incongruence were associated with reductions in psychological distress. In particular, better satisfaction of approach motives mediated the association between reduction of pain interference and psychological distress at post-treatment. Findings suggest that a reduction of motivational incongruence may be part of successful treatment of chronic pain.

show abstract

“…The higher the stage, the more extensive are the required therapeutic interventions, and the less likely is the full recovery from chronic pain [31], [32], [33]. The MPSS’s internal consistency as well as its validity have been confirmed, for example, by Frettlöh et al [33], Hampel et al [34], Schmitt et al [35], and Hüppe et al [36]. …”

Section: Methodsmentioning

confidence: 99%

Subgroups in chronic low back pain patients – a step toward cluster-based, tailored treatment in inpatient standard care: On the need for precise targeting of treatment for chronic low back pain

Langenmaier¹,

Amelung

Karst

et al. 2019

GMS German Medical Science; 17:Doc09

View full text Add to dashboard Cite

Behandlungserfolg auch bei höherer Schmerzchronifizierung?

Cited by 17 publications

References 32 publications

Treatment of peripheral neuropathic pain by topical capsaicin: Impact of pre‐existing pain in the QUEPP‐study

Treatment of peripheral neuropathic pain by topical capsaicin: Impact of pre‐existing pain in the QUEPP‐study

Motive Satisfaction in Chronic Pain Patients: Does It Improve in Multidisciplinary Inpatient Treatment and, if so, Does It Matter?

Subgroups in chronic low back pain patients – a step toward cluster-based, tailored treatment in inpatient standard care: On the need for precise targeting of treatment for chronic low back pain

Contact Info

Product

Resources

About